Specific Information of Small Protein : SPROHSA305117
General Information
| Small Protein ID | SPROHSA305117 |
| Organism | Human (Homo sapiens) |
| Small Protein Sequence | LGRQPLPRTLPGLQHLLGPARSLVSPLGAAAAAVAATRKEVRDAARSPPPPCPRIKVKEVKTDAGVRMRMNLKKENWYSKRMVRSMLR* |
| RNA Sequence | CTGGGTCGCCAGCCTCTCCCGCGCACGTTGCCTGGCCTCCAGCACCTACTTGGTCCCGCGCGCTCCCTCGTGTCGCCCCTCGGAGCAGCAGCCGCCGCGGTCGCCGCTACCCGGAAAGAAGTCAGAGACGCCGCGAGGTCGCCGCCACCGCCATGCCCAAGAATAAAGGTAAAGGAGGTAAAAACAGACGCAGGGGTAAGAATGAGAATGAATCTGAAAAAAGAGAACTGGTATTCAAAGAGGATGGTCAGGAGTATGCTCAGGTAA |
| Protein Length | 88 |
| Start Codon | CTG |
| Location | chrX:20135826-20141792:- |
| Blocks | 20135826-20135841,20138538-20138622,20141624-20141792 |
| Mean PhyloCSF | -7.39010486822 |
| Data Source | Ribosome profiling; |
| Related Genes | ENSG00000173674; EIF1AX; ENSG00000201882; RF00493; ENSG00000201592; RF00494; ENSG00000225037; EIF1AX-AS1; NONHSAG054127;NONHSAG054128;NONHSAG103304; |
| Mass (Da) | mono. 9715.4; avg. 9721.5 |
Ribosome profiling
| Ribo-seq ID | Ensembl Gene ID | Ensembl Transcript ID | Symbol | Gene Type | TIS Type | Ribo P value | TIS P value | Start On Trans | Stop On Trans | In-frame Count | Ribo-seq RPKM |
|---|
| GSE45833_1_alt | ENSG00000173674.11 | ENST00000379607.10 | EIF1AX | Protein_coding | 5'UTR | 0.000108 | None | 46 | 313 | 219 | 128.184186 |
| GSE45833_6_alt | ENSG00000173674.11 | ENST00000379607.10 | EIF1AX | Protein_coding | 5'UTR | 0.000472 | None | 46 | 313 | 155 | 99.1958797 |
| GSE45833_5_alt | ENSG00000173674.11 | ENST00000379607.10 | EIF1AX | Protein_coding | 5'UTR | 0.001764 | None | 46 | 313 | 109 | 157.348303 |
| GSE45833_4_alt | ENSG00000173674.11 | ENST00000379607.10 | EIF1AX | Protein_coding | 5'UTR | 0.003232 | None | 46 | 313 | 91 | 73.6383470 |
| GSE45785_2_alt | ENSG00000173674.11 | ENST00000379607.10 | EIF1AX | Protein_coding | 5'UTR | 0.016678 | None | 46 | 313 | 36 | 79.8166897 |
| GSE45833_3_alt | ENSG00000173674.11 | ENST00000379607.10 | EIF1AX | Protein_coding | 5'UTR | 1.283E-05 | None | 46 | 313 | 143 | 190.397490 |
| SRR4045276_alt | ENSG00000173674.11 | ENST00000379607.10 | EIF1AX | Protein_coding | 5'UTR | 4.018E-05 | None | 46 | 313 | 78 | 69.1895207 |
| GSE123564_1_alt | ENSG00000173674.11 | ENST00000379607.10 | EIF1AX | Protein_coding | 5'UTR | 0.009572 | None | 46 | 313 | 25 | 18.6697870 |
| GSE123564_1 | ENSG00000173674.11 | ENST00000379607.10 | EIF1AX | Protein_coding | 5'UTR | 0.009572 | None | 46 | 313 | 25 | 18.6697870 |
| GSE129869_alt | ENSG00000173674.11 | ENST00000379607.10 | EIF1AX | Protein_coding | 5'UTR | 0.004279 | None | 46 | 313 | 13 | 88.3807620 |
| GSE103308_alt | ENSG00000173674.11 | ENST00000379607.10 | EIF1AX | Protein_coding | 5'UTR | 0.000122 | None | 46 | 313 | 279 | 92.9491247 |
| GSE105082_alt | ENSG00000173674.11 | ENST00000379607.10 | EIF1AX | Protein_coding | 5'UTR | 0.000407 | None | 46 | 313 | 290 | 73.8086140 |
| GSE58207_alt | ENSG00000173674.11 | ENST00000379607.10 | EIF1AX | Protein_coding | 5'UTR | 7.52E-06 | 0.034176 | 46 | 313 | 722 | 278.487882 |
| SRR5350744_alt | ENSG00000173674.11 | ENST00000379607.10 | EIF1AX | Protein_coding | 5'UTR | 0.015911 | None | 46 | 313 | 137 | 199.672114 |
| SRR5350745_alt | ENSG00000173674.11 | ENST00000379607.10 | EIF1AX | Protein_coding | 5'UTR | 7.055E-06 | None | 46 | 313 | 75 | 165.155941 |
| SRR618770,618771,618772,618773_alt | ENSG00000173674.11 | ENST00000379607.10 | EIF1AX | Protein_coding | 5'UTR | 1.381E-05 | 7.165E-08 | 46 | 313 | 937 | 592.441588 |
| SRR964946_alt | ENSG00000173674.11 | ENST00000379607.10 | EIF1AX | Protein_coding | 5'UTR | 0.001061 | 0.009089 | 46 | 313 | NA | NA |
| Min Ribo P value | 7.055E-06 |
| Min TIS P value | 7.165E-08 |
| Ribo-seq ID | Cell or Tissue | Phenotype | Ribo-seq Source Details | PMID |
|---|
| GSE103308_alt | RD-muscle | WT | GSM2760247 | 29696588; |
| GSE105082_alt | HELA | Cervical cancer | GSM2817679; GSM2817680 | 30591072; |
| GSE123564_1 | Skin fibroblasts | WT | GSM3507221; GSM3507222; GSM3507226; GSM3507227 | 30707697; |
| GSE123564_1_alt | Skin fibroblasts | WT | GSM3507221; GSM3507222; GSM3507226; GSM3507227 | 30707697; |
| GSE129869_alt | Foreskin Fibroblasts | WT | GSM3723750; GSM3723751; GSM3723752 | 31167946; |
| GSE45785_2_alt | BJ cells | Immortalized | GSM1115207 | 23594524; |
| GSE45833_1_alt | BJ cells | Proliferation | GSM1047584; GSM1047585 | 23594524; |
| GSE45833_3_alt | BJ cells | Pre-senescence | GSM1047588 | 23594524; |
| GSE45833_4_alt | BJ cells | Proliferation | GSM1047589 | 23594524; |
| GSE45833_5_alt | BJ cells | Senescence | GSM1047590 | 23594524; |
| GSE45833_6_alt | BJ cells | Transformed | GSM1047591 | 23594524; |
| GSE58207_alt | HCT116 | Colorectal carcinoma | GSM1403307; GSM1403308 | 25510491; |
| SRR4045276_alt | Meg01 cells | WT | GSM2285909 | 27681415; |
| SRR5350744_alt | PC9 | NSCLC | GSM2538903 | 28388414; |
| SRR5350745_alt | H1933 | NSCLC | GSM2538904 | 28388414; |
| SRR618770,618771,618772,618773_alt | HEK293 | WT | SRR618770; SRR618771; SRR618772; SRR618773 | NA; |
| SRR964946_alt | HEK293 | WT | SRR964946 | 22927429; |
Mass Spectrometry Information
Function and Disease
| Functional domain prediction |  |
| Analysis | Signature Accession | Signature Description | Start location | Stop location | Score | Status of the match | InterPro accession | InterPro description | GO | Pathways |
|---|
| No results |
| Disease | Detected |
|---|
| No results |
Related Variants
| Variant ID | Consequence to sORF | rsID | Ribo-seq ID |
|---|
| No results |
Related Small Proteins with Different TISs
SmProt