SmProt

Specific Information of Small Protein : SPROHSA195098

General Information

Small Protein ID	SPROHSA195098
Organism	Human (Homo sapiens)
Small Protein Sequence	MASKPEKRVASSVFITL
RNA Sequence	ATGGCCTCAAAGCCTGAGAAGAGGGTGGCATCGTCTGTCTTTATCACCCTG
Protein Length	17
Start Codon	ATG
Location	chr1:15764983-15765034:+
Blocks	15764983-15765034
Mean PhyloCSF	7.04582347589
Data Source	Ribosome profiling;
Related Genes	ENSG00000162458; FBLIM1;
Mass (Da)	mono. 1863; avg. 1864.2

Ribosome profiling

Ribo-seq ID	Ensembl Gene ID	Ensembl Transcript ID	Symbol	Gene Type	TIS Type	Ribo P value	TIS P value	Start On Trans	Stop On Trans	In-frame Count	Ribo-seq RPKM
GSE45785_5	ENSG00000162458.13	ENST00000430076.5	FBLIM1	Protein_coding	Annotated	0.002969	None	455	506	14	284.379183
GSE45785_5_alt	ENSG00000162458.13	ENST00000430076.5	FBLIM1	Protein_coding	Annotated	0.002969	None	455	506	14	284.379183
GSE45785_2	ENSG00000162458.13	ENST00000430076.5	FBLIM1	Protein_coding	Annotated	0.00417	None	455	506	47	545.544466
GSE45785_1	ENSG00000162458.13	ENST00000430076.5	FBLIM1	Protein_coding	Annotated	0.00436	None	455	506	42	539.905994
GSE45785_1_alt	ENSG00000162458.13	ENST00000430076.5	FBLIM1	Protein_coding	Annotated	0.00436	None	455	506	42	539.905994
GSE45833_2	ENSG00000162458.13	ENST00000430076.5	FBLIM1	Protein_coding	Annotated	0.032653	None	455	506	17	45.7735559
GSE45785_4	ENSG00000162458.13	ENST00000430076.5	FBLIM1	Protein_coding	Annotated	0.032887	None	455	506	56	700.316735
GSE103308	ENSG00000162458.13	ENST00000430076.5	FBLIM1	Protein_coding	Annotated	0.009524	None	455	506	8	13.9531471
GSE94454	ENSG00000162458.13	ENST00000430076.5	FBLIM1	Protein_coding	Annotated	0.032653	None	455	506	4	3.49142645
SRR5047771	ENSG00000162458.13	ENST00000430076.5	FBLIM1	Protein_coding	Annotated	0.000564	None	455	506	18	16.1407780
SRR5047770	ENSG00000162458.13	ENST00000430076.5	FBLIM1	Protein_coding	Annotated	0.02522	None	455	506	6	9.33414050
SRR7207252	ENSG00000162458.13	ENST00000430076.5	FBLIM1	Protein_coding	Annotated	0.000975	None	455	506	16	82.9658503
SRR7207252_alt	ENSG00000162458.13	ENST00000430076.5	FBLIM1	Protein_coding	Annotated	0.000975	None	455	506	16	82.9658503
GSE83493	ENSG00000162458.13	ENST00000430076.5	FBLIM1	Protein_coding	Annotated	0.034825	None	455	506	12	28.1978271
GSE83493_alt	ENSG00000162458.13	ENST00000430076.5	FBLIM1	Protein_coding	Annotated	0.034825	None	455	506	12	28.1978271
SRR2991181	ENSG00000162458.13	ENST00000430076.5	FBLIM1	Protein_coding	Annotated	0.032653	None	455	506	20	64.0971688
SRR5350744	ENSG00000162458.13	ENST00000430076.5	FBLIM1	Protein_coding	Annotated	0.000778	None	455	506	16	122.083766
SRR5350744_alt	ENSG00000162458.13	ENST00000430076.5	FBLIM1	Protein_coding	Annotated	0.000778	None	455	506	16	122.083766
SRR618770,618771,618772,618773_alt	ENSG00000162458.13	ENST00000430076.5	FBLIM1	Protein_coding	Annotated	0.022006	0.013231	455	506	29	95.9942080

Min Ribo P value	0.000564
Min TIS P value	None

Ribo-seq ID	Cell or Tissue	Phenotype	Ribo-seq Source Details	PMID
GSE103308	RD-muscle	WT	GSM2760247	29696588;
GSE45785_1	BJ cells	WT	GSM1115204	23594524;
GSE45785_1_alt	BJ cells	WT	GSM1115204	23594524;
GSE45785_2	BJ cells	Immortalized	GSM1115207	23594524;
GSE45785_4	BJ cells	Immortalized	GSM1115213	23594524;
GSE45785_5	BJ cells	Immortalized	GSM1115216	23594524;
GSE45785_5_alt	BJ cells	Immortalized	GSM1115216	23594524;
GSE45833_2	BJ cells	Quiescence	GSM1047586; GSM1047587	23594524;
GSE83493	HeLa S3	Cervical cancer	GSM2204389; GSM2204390; GSM2204391; GSM2204392	28460002;
GSE83493_alt	HeLa S3	Cervical cancer	GSM2204389; GSM2204390; GSM2204391; GSM2204392	28460002;
GSE94454	Huh7	Hepatoma	GSM2476003; GSM2476004; GSM2476005	28323820;
SRR2991181	SH-SY5Y	Neuroblastoma	GSM1970518	31109297;
SRR5047770	iPSC-differentiated dopamine neurons	Parkinson Disease	GSM2402496; GSM2402497; GSM2402498	NA;
SRR5047771	iPSC-differentiated dopamine neurons	Parkinson Disease	NA	NA;
SRR5350744	PC9	NSCLC	GSM2538903	28388414;
SRR5350744_alt	PC9	NSCLC	GSM2538903	28388414;
SRR618770,618771,618772,618773_alt	HEK293	WT	SRR618770; SRR618771; SRR618772; SRR618773	NA;
SRR7207252	MCF10A-ER-Src	Breast adenocarcinoma	GSM3150265	30089253;
SRR7207252_alt	MCF10A-ER-Src	Breast adenocarcinoma	GSM3150265	30089253;

Database information

No results

Literature information

No results

Mass Spectrometry Information

No results

Function and Disease

Functional domain prediction

Analysis	Signature Accession	Signature Description	Start location	Stop location	Score	Status of the match	InterPro accession	InterPro description	GO	Pathways
No results

Disease	Detected
No results

Related Variants

Variant ID	Consequence to sORF	rsID	Ribo-seq ID
No results

Related Small Proteins with Different TISs

SmProt ID	Small Protein Length	Start Codon	Strand	Blocks
SPROHSA92855	10	AGG	+	15765004-15765034
SPROHSA11265	11	AAG	+	15765001-15765034
SPROHSA19780	14	AAG	+	15764992-15765034
SPROHSA240027	25	ATT	+	15764681-15764685, 15764963-15765034
SPROHSA117830	26	ATC	+	15764678-15764685, 15764963-15765034
SPROHSA327249	27	GTG	+	15764675-15764685, 15764963-15765034
SPROHSA324758	32	GTG	+	15764660-15764685, 15764963-15765034
SPROHSA134339	39	ATC	+	15764639-15764685, 15764963-15765034

a reliable repository with comprehensive annotation of small proteins derived from ribosome profiling