SmProt

Specific Information of Small Protein : SPROHSA130277

General Information

Small Protein ID	SPROHSA130277
Organism	Human (Homo sapiens)
Small Protein Sequence	IYATRSGGTLVLVGLGSEMTTVPLLHAAIREVDIKGVFRYCNTWPVAISMLASKSVNVKPLVTHRFPLEKALEAFETFKKGLGLKIMLKCDPSDQNP*
RNA Sequence	ATCTACGCCACTCGCTCTGGTGGGACCCTCGTGCTTGTGGGGCTGGGCTCTGAGATGACCACCGTACCCCTACTGCATGCAGCCATCCGGGAGGTGGATATCAAGGGCGTGTTTCGATACTGCAACACGTGGCCAGTGGCGATTTCGATGCTTGCGTCCAAGTCTGTGAATGTAAAACCCCTCGTCACCCATAGGTTTCCTCTGGAGAAAGCTCTGGAGGCCTTTGAAACATTTAAAAAGGGATTGGGGTTGAAAATCATGCTCAAGTGTGACCCCAGTGACCAGAATCCCTGA
Protein Length	97
Start Codon	ATC
Location	chr15:44827055-44831534:-
Blocks	44827055-44827221,44828449-44828571,44831528-44831534
Mean PhyloCSF	-2.39720069551
Data Source	Ribosome profiling;
Related Genes	ENSG00000259479; SORD2P; ENSG00000259187; AC122108.1; NONHSAG016753;NONHSAG016754;
Mass (Da)	mono. 10623.7; avg. 10630.5

Ribosome profiling

Ribo-seq ID	Ensembl Gene ID	Ensembl Transcript ID	Symbol	Gene Type	TIS Type	Ribo P value	TIS P value	Start On Trans	Stop On Trans	In-frame Count	Ribo-seq RPKM
GSE45833_6_alt	ENSG00000259479.6	ENST00000561384.3	SORD2P	Transcribed_unprocessed_pseudogene	Novel	0.03628	None	895	1189	4	2.32480139
SRR4045276_alt	ENSG00000259479.6	ENST00000561384.3	SORD2P	Transcribed_unprocessed_pseudogene	Novel	2.706E-12	None	895	1189	76	61.2242175
SRR3208921_alt	ENSG00000259479.6	ENST00000561384.3	SORD2P	Transcribed_unprocessed_pseudogene	Novel	0.000206	None	895	1189	15	11.3410338
GSE103308_alt	ENSG00000259479.6	ENST00000561384.3	SORD2P	Transcribed_unprocessed_pseudogene	Novel	4.978E-09	None	895	1189	187	56.5778759
GSE105082_alt	ENSG00000259479.6	ENST00000561384.3	SORD2P	Transcribed_unprocessed_pseudogene	Novel	7.007E-12	None	895	1189	138	31.8971638
GSE65778	ENSG00000259479.6	ENST00000561384.3	SORD2P	Transcribed_unprocessed_pseudogene	Novel	0.0025	None	895	1189	78	46.5241284
GSE94454_alt	ENSG00000259479.6	ENST00000561384.3	SORD2P	Transcribed_unprocessed_pseudogene	Novel	1.194E-23	None	895	1189	440	66.6221171
GSE94613_2_alt	ENSG00000259479.6	ENST00000561384.3	SORD2P	Transcribed_unprocessed_pseudogene	Novel	0.004857	None	895	1189	68	48.1282673
GSE94613_1_alt	ENSG00000259479.6	ENST00000561384.3	SORD2P	Transcribed_unprocessed_pseudogene	Novel	0.011871	None	895	1189	19	37.3307576
GSE83493_alt	ENSG00000259479.6	ENST00000561384.3	SORD2P	Transcribed_unprocessed_pseudogene	Novel	7.991E-05	None	895	1189	123	50.1374629

Min Ribo P value	1.194E-23
Min TIS P value	None

Ribo-seq ID	Cell or Tissue	Phenotype	Ribo-seq Source Details	PMID
GSE103308_alt	RD-muscle	WT	GSM2760247	29696588;
GSE105082_alt	HELA	Cervical cancer	GSM2817679; GSM2817680	30591072;
GSE45833_6_alt	BJ cells	Transformed	GSM1047591	23594524;
GSE65778	HEK293T	WT	GSM1606107; GSM1606108	25719440;
GSE83493_alt	HeLa S3	Cervical cancer	GSM2204389; GSM2204390; GSM2204391; GSM2204392	28460002;
GSE94454_alt	Huh7	Hepatoma	GSM2476003; GSM2476004; GSM2476005	28323820;
GSE94613_1_alt	MOLM13	Acute myeloid leukemia	GSM2481052	29186125;
GSE94613_2_alt	MOLM13	Acute myeloid leukemia	GSM2481053	29186125;
SRR3208921_alt	ES cell-derived neurons TSC2-/-	Tuberous sclerosis complex	GSM2082573	27655340;
SRR4045276_alt	Meg01 cells	WT	GSM2285909	27681415;

Database information

No results

Literature information

No results

Mass Spectrometry Information

MS ID	Seq	Length	Chr	Start	Stop	Strand
MSHSA415549	SGGTLVLVGLGSEMTTVPLLHAAIR	25	chr15	44828488	44828562	-

Function and Disease

Functional domain prediction

Analysis	Signature Accession	Start location	Stop location	Score	Status of the match
Gene3D	G3DSA:3.90.180.10	40	78	7.5E-22	T
PANTHER	PTHR43161	1	93	4.2E-31	T
Gene3D	G3DSA:3.40.50.720	1	37	7.5E-22	T
PANTHER	PTHR43161:SF9	1	93	4.2E-31	T

Disease	Detected
No results

Related Variants

Variant ID	Consequence to sORF	rsID	Ribo-seq ID
No results

Related Small Proteins with Different TISs

SmProt ID	Small Protein Length	Start Codon	Strand	Blocks
SPROHSA117403	12	ATC	+	45073491-45073530
SPROHSA387281	16	TTG	-	44827055-44827106
SPROHSA34778	18	AAG	-	44827055-44827112
SPROHSA34779	18	AAG	+	45073473-45073530
SPROHSA288736	26	CTG	-	44827055-44827136
SPROHSA288737	26	CTG	+	45073449-45073530
SPROHSA178714	48	ATG	-	44827055-44827202
SPROHSA246377	50	ATT	+	45073377-45073530
SPROHSA60935	55	ACG	+	45072436-45072438, 45073364-45073530
SPROHSA112150	64	ATC	+	45072409-45072438, 45073364-45073530
SPROHSA267355	73	CTG	-	44827055-44827221, 44828449-44828505
SPROHSA147008	79	ATG	-	44827055-44827221, 44828449-44828523
SPROHSA302475	83	CTG	-	44827055-44827221, 44828449-44828535
SPROHSA302476	83	CTG	+	45072352-45072438, 45073364-45073530
SPROHSA356118	85	GTG	-	44827055-44827221, 44828449-44828541
SPROHSA339130	87	GTG	-	44827055-44827221, 44828449-44828547