Specific Information of Small Protein : SPROHSA127930
General Information
| Small Protein ID | SPROHSA127930 |
| Organism | Human (Homo sapiens) |
| Small Protein Sequence | IAGVTCAEQLATHFPSEDILLVTASPVMKAVTNFKQISKILEEFDVEEQSSTMLEKRFPNIKVIESGVKQLKSEEHCIVTEDGNQHVYKKLCVLELNQS* |
| RNA Sequence | ATCGCGGGCGTCACTTGTGCGGAGCAGTTGGCTACTCACTTTCCATCAGAAGATATTCTCTTGGTAACAGCTTCTCCTGTTATGAAAGCAGTTACAAATTTCAAGCAGATTTCTAAAATATTGGAAGAATTTGATGTTGAAGAACAATCAAGTACCATGTTAGAAAAACGCTTTCCCAACATCAAGGTTATAGAATCTGGCGTAAAGCAACTGAAGAGTGAAGAACACTGCATTGTAACAGAAGATGGCAATCAGCATGTATATAAGAAACTCTGTGTGCTGGAGCTAAACCAAAGTTGA |
| Protein Length | 99 |
| Start Codon | ATC |
| Location | chr11:106827533-106827833:- |
| Blocks | 106827533-106827833 |
| Mean PhyloCSF | 0 |
| Data Source | Ribosome profiling; |
| Related Genes | ENSG00000152402; GUCY1A2; ENSG00000213252; AP001282.1; |
| Mass (Da) | mono. 11098.7; avg. 11105.6 |
Ribosome profiling
| Ribo-seq ID | Ensembl Gene ID | Ensembl Transcript ID | Symbol | Gene Type | TIS Type | Ribo P value | TIS P value | Start On Trans | Stop On Trans | In-frame Count | Ribo-seq RPKM |
|---|
| GSE45785_1_alt | ENSG00000213252.3 | ENST00000531301.1 | AP001282.1 | Processed_pseudogene | Novel | 0.023934 | None | 57 | 357 | 7 | 15.2973365 |
| GSE45785_3_alt | ENSG00000213252.3 | ENST00000531301.1 | AP001282.1 | Processed_pseudogene | Novel | 0.036295 | None | 57 | 357 | 10 | 14.0581608 |
| SRR4045276_alt | ENSG00000213252.3 | ENST00000531301.1 | AP001282.1 | Processed_pseudogene | Novel | 0.042149 | None | 57 | 357 | 7 | 5.52629121 |
| GSE123564_2_alt | ENSG00000213252.3 | ENST00000531301.1 | AP001282.1 | Processed_pseudogene | Novel | 0.000888 | None | 57 | 357 | 15 | 7.16776923 |
| GSE105082_alt | ENSG00000213252.3 | ENST00000531301.1 | AP001282.1 | Processed_pseudogene | Novel | 2.373E-05 | None | 57 | 357 | 28 | 6.34245056 |
| GSE94613_2_alt | ENSG00000213252.3 | ENST00000531301.1 | AP001282.1 | Processed_pseudogene | Novel | 0.037974 | None | 57 | 357 | 15 | 10.4041989 |
| GSE83493_alt | ENSG00000213252.3 | ENST00000531301.1 | AP001282.1 | Processed_pseudogene | Novel | 0.005225 | None | 57 | 357 | 24 | 9.58726121 |
| SRR5350745_alt | ENSG00000213252.3 | ENST00000531301.1 | AP001282.1 | Processed_pseudogene | Novel | 0.010848 | None | 57 | 357 | 42 | 82.3137211 |
| Min Ribo P value | 2.373E-05 |
| Min TIS P value | None |
| Ribo-seq ID | Cell or Tissue | Phenotype | Ribo-seq Source Details | PMID |
|---|
| GSE105082_alt | HELA | Cervical cancer | GSM2817679; GSM2817680 | 30591072; |
| GSE123564_2_alt | Skin fibroblasts: Hbs1L-deficient | Facial dysmorphism, growth restriction and retinal deposits | GSM3507223; GSM3507224; GSM3507225; GSM3507228; GSM3507229; GSM3507230 | 30707697; |
| GSE45785_1_alt | BJ cells | WT | GSM1115204 | 23594524; |
| GSE45785_3_alt | BJ cells | Immortalized | GSM1115210 | 23594524; |
| GSE83493_alt | HeLa S3 | Cervical cancer | GSM2204389; GSM2204390; GSM2204391; GSM2204392 | 28460002; |
| GSE94613_2_alt | MOLM13 | Acute myeloid leukemia | GSM2481053 | 29186125; |
| SRR4045276_alt | Meg01 cells | WT | GSM2285909 | 27681415; |
| SRR5350745_alt | H1933 | NSCLC | GSM2538904 | 28388414; |
Mass Spectrometry Information
Function and Disease
| Functional domain prediction |  |
| Analysis | Signature Accession | Signature Description | Start location | Stop location | Score | Status of the match | InterPro accession | InterPro description | GO | Pathways |
|---|
| PANTHER | PTHR43429:SF2 | | 1 | 93 | 7.2E-39 | T | | | | |
| SUPERFAMILY | SSF51905 | | 1 | 92 | 9.58E-5 | T | IPR036188 | FAD/NAD(P)-binding domain superfamily | | |
| Gene3D | G3DSA:3.50.50.60 | | 1 | 95 | 1.2E-5 | T | IPR036188 | FAD/NAD(P)-binding domain superfamily | | |
| PANTHER | PTHR43429 | | 1 | 93 | 7.2E-39 | T | | | | |
| Disease | Detected |
|---|
| No results |
Related Variants
| Variant ID | Consequence to sORF | rsID | Ribo-seq ID |
|---|
| 11-106827786-T-C | Synonymous p.S16S | . | SRR5239056; SRR5239058; SRR5350740; SRR5350744; SRR5350745; SRR8310198; SRR810101; SRR810102; SRR810104 |
Related Small Proteins with Different TISs
SmProt