Specific Information of Small Protein : SPROHSA26998
General Information
| Small Protein ID | SPROHSA26998 |
| Organism | Human (Homo sapiens) |
| Small Protein Sequence | KDYTKAMDVYQKALDLDSSCKEAADGYQRCMMAQYNRHDSPEDVKRRAMADPEVQQIMSDPAMRLILEQMQKDPQALSEYVESERRPCWKWRTKAGR* |
| RNA Sequence | AAGGACTACACCAAAGCCATGGATGTGTACCAGAAGGCGCTAGACCTGGACTCCAGCTGTAAGGAGGCGGCAGACGGCTACCAGCGCTGTATGATGGCGCAGTACAACCGGCACGACAGCCCCGAAGATGTGAAGCGACGAGCCATGGCCGACCCTGAGGTGCAGCAGATCATGAGTGACCCAGCCATGCGCCTTATCCTGGAACAGATGCAGAAGGACCCCCAGGCACTCAGCGAGTACGTAGAGTCAGAGAGGCGGCCTTGCTGGAAATGGAGAACAAAAGCAGGCAGATGA |
| Protein Length | 97 |
| Start Codon | AAG |
| Location | chr11:64203165-64203680:+ |
| Blocks | 64203165-64203228,64203449-64203680 |
| Mean PhyloCSF | 4.39330223004 |
| Data Source | Ribosome profiling; |
| Related Genes | ENSG00000168439; STIP1; |
| Mass (Da) | mono. 11412.4; avg. 11419.9 |
Ribosome profiling
| Ribo-seq ID | Ensembl Gene ID | Ensembl Transcript ID | Symbol | Gene Type | TIS Type | Ribo P value | TIS P value | Start On Trans | Stop On Trans | In-frame Count | Ribo-seq RPKM |
|---|
| GSE74365_alt | ENSG00000168439.16 | ENST00000540887.1 | STIP1 | Protein_coding | Truncated | 0.029402 | 0.039368 | 120 | 414 | NA | NA |
| GSE119615_2_alt | ENSG00000168439.16 | ENST00000540887.1 | STIP1 | Protein_coding | Truncated | 0.002339 | 0.042869 | 120 | 414 | 25 | 100.672595 |
| Min Ribo P value | 0.002339 |
| Min TIS P value | 0.039368 |
| Ribo-seq ID | Cell or Tissue | Phenotype | Ribo-seq Source Details | PMID |
|---|
| GSE119615_2_alt | RA-differentiated SH-SY5Y cells | Neuroblastoma | GSM3378861; GSM3378862; GSM3378863; GSM3378864 | 31109297; |
| GSE74365_alt | Cystic Fibrosis Bronchial Epithelial cells | Cystic Fibrosi | GSM1918965; GSM1918969 | 28510592; |
Mass Spectrometry Information
Function and Disease
| Functional domain prediction |  |
| Analysis | Signature Accession | Signature Description | Start location | Stop location | Score | Status of the match | InterPro accession | InterPro description | GO | Pathways |
|---|
| PANTHER | PTHR22904:SF517 | | 1 | 82 | 4.3E-52 | T | | | | |
| PANTHER | PTHR22904 | | 1 | 82 | 4.3E-52 | T | | | | |
| Gene3D | G3DSA:1.10.260.100 | | 36 | 86 | 2.7E-15 | T | | | | |
| ProSiteProfiles | PS50293 | TPR repeat region circular profile. | 1 | 20 | 9.53 | T | IPR013026 | Tetratricopeptide repeat-containing domain | GO:0005515 | |
| Pfam | PF17830 | STI1 domain | 42 | 81 | 8.2E-14 | T | IPR041243 | STI1 domain | | |
| Gene3D | G3DSA:1.25.40.10 | | 1 | 35 | 1.9E-8 | T | IPR011990 | Tetratricopeptide-like helical domain superfamily | GO:0005515 | |
| Disease | Detected |
|---|
| No results |
Related Variants
| Variant ID | Consequence to sORF | rsID | Ribo-seq ID |
|---|
| 11-64203623-G-A | Synonymous p.E79E | . | SRR5239056; SRR3680966; SRR3680967; SRR810103; SRR810104 |
| 11-64203624-T-C | Non-Synonymous p.Y80H | . | SRR5239056; SRR3680966; SRR3680967; SRR810103; SRR810104 |
Related Small Proteins with Different TISs
| SmProt ID | Small Protein Length | Start Codon | Strand | Blocks |
|---|
| SPROHSA320601 | 54 | GTG | + | 64203515-64203680 |
| SPROHSA190163 | 91 | ATG | + | 64203183-64203228, 64203449-64203680 |
| SPROHSA142288 | 98 | ATG | + | 64203162-64203228, 64203449-64203680 |
SmProt