Specific Information of Small Protein : SPROHSA142288
General Information
Small Protein IDSPROHSA142288
OrganismHuman (Homo sapiens)
Small Protein SequenceMKDYTKAMDVYQKALDLDSSCKEAADGYQRCMMAQYNRHDSPEDVKRRAMADPEVQQIMSDPAMRLILEQMQKDPQALSEYVESERRPCWKWRTKAGR*
RNA SequenceATGAAGGACTACACCAAAGCCATGGATGTGTACCAGAAGGCGCTAGACCTGGACTCCAGCTGTAAGGAGGCGGCAGACGGCTACCAGCGCTGTATGATGGCGCAGTACAACCGGCACGACAGCCCCGAAGATGTGAAGCGACGAGCCATGGCCGACCCTGAGGTGCAGCAGATCATGAGTGACCCAGCCATGCGCCTTATCCTGGAACAGATGCAGAAGGACCCCCAGGCACTCAGCGAGTACGTAGAGTCAGAGAGGCGGCCTTGCTGGAAATGGAGAACAAAAGCAGGCAGATGA
Protein Length98
Start CodonATG
Locationchr11:64203162-64203680:+
Blocks64203162-64203228,64203449-64203680
Mean PhyloCSF4.41531937876
Data SourceRibosome profiling; Literature;
Related GenesENSG00000168439; STIP1;
Mass (Da)mono. 11543.5; avg. 11551.1
Ribosome profiling
Ribo-seq IDEnsembl Gene IDEnsembl Transcript IDSymbolGene TypeTIS TypeRibo P valueTIS P valueStart On TransStop On TransIn-frame CountRibo-seq RPKM
SRR5512738ENSG00000168439.16ENST00000540887.1STIP1Protein_codingTruncated1.665E-08None11741422997.7443595
SRR3208885ENSG00000168439.16ENST00000540887.1STIP1Protein_codingTruncated1.106E-12None117414248150.020074
GSE45833_1ENSG00000168439.16ENST00000540887.1STIP1Protein_codingTruncated0.000266None117414702369.387557
GSE45785_3ENSG00000168439.16ENST00000540887.1STIP1Protein_codingTruncated0.000365None117414144204.482339
GSE45785_2ENSG00000168439.16ENST00000540887.1STIP1Protein_codingTruncated0.001888None117414117233.201793
GSE45785_5ENSG00000168439.16ENST00000540887.1STIP1Protein_codingTruncated0.002485None11741454188.355043
GSE45785_4ENSG00000168439.16ENST00000540887.1STIP1Protein_codingTruncated0.005321None11741468146.025639
GSE45785_1ENSG00000168439.16ENST00000540887.1STIP1Protein_codingTruncated0.005494None11741490198.666707
SRR3317843ENSG00000168439.16ENST00000540887.1STIP1Protein_codingTruncated1.035E-08None11741491257.850502
SRR4045276ENSG00000168439.16ENST00000540887.1STIP1Protein_codingTruncated2.422E-24None117414398317.382958
GSE45833_6ENSG00000168439.16ENST00000540887.1STIP1Protein_codingTruncated2.439E-05None117414291167.420924
GSE45833_2ENSG00000168439.16ENST00000540887.1STIP1Protein_codingTruncated3.435E-08None117414654302.382884
GSE45833_4ENSG00000168439.16ENST00000540887.1STIP1Protein_codingTruncated5.117E-07None117414177128.762890
SRR3208921ENSG00000168439.16ENST00000540887.1STIP1Protein_codingTruncated8.528E-14None117414295220.787400
GSE123564_2ENSG00000168439.16ENST00000540887.1STIP1Protein_codingTruncated5.938E-05None117414446215.274416
GSE103308ENSG00000168439.16ENST00000540887.1STIP1Protein_codingTruncated4.647E-10None1174141249374.074713
GSE105082ENSG00000168439.16ENST00000540887.1STIP1Protein_codingTruncated1.118E-12None1174142018461.726739
GSE94454ENSG00000168439.16ENST00000540887.1STIP1Protein_codingTruncated2.961E-18None1174141690253.304752
SRR5047770ENSG00000168439.16ENST00000540887.1STIP1Protein_codingTruncated1.415E-11None117414809216.115209
SRR5047771ENSG00000168439.16ENST00000540887.1STIP1Protein_codingTruncated1.961E-11None1174141385213.262973
SRR5047772ENSG00000168439.16ENST00000540887.1STIP1Protein_codingTruncated4.451E-07None117414216128.598429
GSE94613_2ENSG00000168439.16ENST00000540887.1STIP1Protein_codingTruncated0.000112None117414253177.256723
GSE104033ENSG00000168439.16ENST00000540887.1STIP1Protein_codingTruncated1.511E-09None117414252429.213358
GSE94613_1ENSG00000168439.16ENST00000540887.1STIP1Protein_codingTruncated7.735E-05None117414107208.107562
SRR7207252ENSG00000168439.16ENST00000540887.1STIP1Protein_codingTruncated5.11E-06None117414171152.261191
SRR5350740ENSG00000168439.16ENST00000540887.1STIP1Protein_codingTruncated1.022E-06None117414251310.588619
SRR4045277ENSG00000168439.16ENST00000540887.1STIP1Protein_codingTruncated3.091E-13None11741471724.822215
GSE83493ENSG00000168439.16ENST00000540887.1STIP1Protein_codingTruncated2.082E-07None1174141105445.872207
GSE119615_1_altENSG00000168439.16ENST00000540887.1STIP1Protein_codingTruncated0.0362880.00924811741413150.431466
SRR2991181ENSG00000168439.16ENST00000540887.1STIP1Protein_codingTruncated1.429E-11None117414658362.116631
SRR5350744ENSG00000168439.16ENST00000540887.1STIP1Protein_codingTruncated0.010957None117414368482.169217
SRR5350745ENSG00000168439.16ENST00000540887.1STIP1Protein_codingTruncated3.83E-07None117414103203.903638
GSE97140ENSG00000168439.16ENST00000540887.1STIP1Protein_codingTruncated3.628E-10None117414252429.163209
Min Ribo P value2.422E-24
Min TIS P valueNone
Ribo-seq IDCell or TissuePhenotypeRibo-seq Source DetailsPMID
GSE103308RD-muscleWTGSM276024729696588;
GSE104033HAP-1 cellsChronic myeloid leukemiaGSM2788007; GSM278800830143613;
GSE105082HELACervical cancerGSM2817679; GSM281768030591072;
GSE119615_1_altNon-differentiated SH-SY5Y cellsNeuroblastomaGSM3378857; GSM3378858; GSM3378859; GSM337886031109297;
GSE123564_2Skin fibroblasts: Hbs1L-deficientFacial dysmorphism, growth restriction and retinal depositsGSM3507223; GSM3507224; GSM3507225; GSM3507228; GSM3507229; GSM350723030707697;
GSE45785_1BJ cellsWTGSM111520423594524;
GSE45785_2BJ cellsImmortalizedGSM111520723594524;
GSE45785_3BJ cellsImmortalizedGSM111521023594524;
GSE45785_4BJ cellsImmortalizedGSM111521323594524;
GSE45785_5BJ cellsImmortalizedGSM111521623594524;
GSE45833_1BJ cellsProliferationGSM1047584; GSM104758523594524;
GSE45833_2BJ cellsQuiescenceGSM1047586; GSM104758723594524;
GSE45833_4BJ cellsProliferationGSM104758923594524;
GSE45833_6BJ cellsTransformedGSM104759123594524;
GSE83493HeLa S3Cervical cancerGSM2204389; GSM2204390; GSM2204391; GSM220439228460002;
GSE94454Huh7HepatomaGSM2476003; GSM2476004; GSM247600528323820;
GSE94613_1MOLM13Acute myeloid leukemiaGSM248105229186125;
GSE94613_2MOLM13Acute myeloid leukemiaGSM248105329186125;
GSE97140Flp-In T-REx-293WTGSM2552194; GSM255219528520920;
SRR2991181SH-SY5YNeuroblastomaGSM197051831109297;
SRR3208885ES cell-derived neurons TSC2+/+WTGSM208253727655340;
SRR3208921ES cell-derived neurons TSC2-/-Tuberous sclerosis complexGSM208257327655340;
SRR3317843U2OS cellsWTGSM210308027406171;
SRR4045276Meg01 cellsWTGSM228590927681415;
SRR4045277platelet-like particlesWTGSM228591027681415;
SRR5047770iPSC-differentiated dopamine neuronsParkinson DiseaseGSM2402496; GSM2402497; GSM2402498NA;
SRR5047771iPSC-differentiated dopamine neuronsParkinson DiseaseNANA;
SRR5047772iPSC-differentiated dopamine neuronsParkinson DiseaseNANA;
SRR5350740MCF7Breast adenocarcinomaGSM253888428388414;
SRR5350744PC9NSCLCGSM253890328388414;
SRR5350745H1933NSCLCGSM253890428388414;
SRR5512738GM19147-Lymphoblastoid Cell LineWTGSM260131229950183;
SRR7207252MCF10A-ER-SrcBreast adenocarcinomaGSM315026530089253;

Database information
No results
Literature information
PMID26364619;
Cell lines Or TissuesNA
PhenotypeNULL
Gene IDENSG00000168439
Transcript IDENST00000540887
SymbolNA
ORF TypesORF
Gene Typeprotein_coding
ThroughputHigh-throughput Literature Mining
InteractionNA
Function DescriptionNA
Mass Spectrometry Information
No results
Function and Disease
Functional domain prediction Funtion   
AnalysisSignature AccessionSignature DescriptionStart locationStop locationScoreStatus of the matchInterPro accessionInterPro descriptionGOPathways
PANTHERPTHR22904:SF5171838.7E-53T
PANTHERPTHR229041838.7E-53T
Gene3DG3DSA:1.10.260.10037872.8E-15T
ProSiteProfilesPS50293TPR repeat region circular profile.1219.665TIPR013026Tetratricopeptide repeat-containing domainGO:0005515
Gene3DG3DSA:1.25.40.101364.5E-9TIPR011990Tetratricopeptide-like helical domain superfamilyGO:0005515
PfamPF17830STI1 domain43828.4E-14TIPR041243STI1 domain
DiseaseDetected
No results
Related Variants
Variant IDConsequence to sORFrsIDRibo-seq ID
11-64203623-G-ASynonymous p.E80E.SRR5239056; SRR3680966; SRR3680967; SRR810103; SRR810104
11-64203624-T-CNon-Synonymous p.Y81H.SRR5239056; SRR3680966; SRR3680967; SRR810103; SRR810104
Related Small Proteins with Different TISs
SmProt IDSmall Protein LengthStart CodonStrandBlocks
SPROHSA32060154GTG+64203515-64203680
SPROHSA19016391ATG+64203183-64203228, 64203449-64203680
SPROHSA2699897AAG+64203165-64203228, 64203449-64203680