Specific Information of Small Protein : SPROHSA190163
General Information
| Small Protein ID | SPROHSA190163 |
| Organism | Human (Homo sapiens) |
| Small Protein Sequence | MDVYQKALDLDSSCKEAADGYQRCMMAQYNRHDSPEDVKRRAMADPEVQQIMSDPAMRLILEQMQKDPQALSEYVESERRPCWKWRTKAGR* |
| RNA Sequence | ATGGATGTGTACCAGAAGGCGCTAGACCTGGACTCCAGCTGTAAGGAGGCGGCAGACGGCTACCAGCGCTGTATGATGGCGCAGTACAACCGGCACGACAGCCCCGAAGATGTGAAGCGACGAGCCATGGCCGACCCTGAGGTGCAGCAGATCATGAGTGACCCAGCCATGCGCCTTATCCTGGAACAGATGCAGAAGGACCCCCAGGCACTCAGCGAGTACGTAGAGTCAGAGAGGCGGCCTTGCTGGAAATGGAGAACAAAAGCAGGCAGATGA |
| Protein Length | 91 |
| Start Codon | ATG |
| Location | chr11:64203183-64203680:+ |
| Blocks | 64203183-64203228,64203449-64203680 |
| Mean PhyloCSF | 4.17480020272 |
| Data Source | Ribosome profiling; |
| Related Genes | ENSG00000168439; STIP1; |
| Mass (Da) | mono. 10706.1; avg. 10713.1 |
Ribosome profiling
| Ribo-seq ID | Ensembl Gene ID | Ensembl Transcript ID | Symbol | Gene Type | TIS Type | Ribo P value | TIS P value | Start On Trans | Stop On Trans | In-frame Count | Ribo-seq RPKM |
|---|
| GSE45833_5 | ENSG00000168439.16 | ENST00000540887.1 | STIP1 | Protein_coding | Truncated | 6.597E-07 | None | 138 | 414 | 87 | 121.494606 |
| GSE45833_3 | ENSG00000168439.16 | ENST00000540887.1 | STIP1 | Protein_coding | Truncated | 8.194E-08 | None | 138 | 414 | 304 | 391.562366 |
| SRR6838651 | ENSG00000168439.16 | ENST00000540887.1 | STIP1 | Protein_coding | Truncated | 4.397E-05 | None | 138 | 414 | 20 | 217.038616 |
| SRR6838651_alt | ENSG00000168439.16 | ENST00000540887.1 | STIP1 | Protein_coding | Truncated | 4.397E-05 | None | 138 | 414 | 20 | 217.038616 |
| GSE119615_1_alt | ENSG00000168439.16 | ENST00000540887.1 | STIP1 | Protein_coding | Truncated | 0.036231 | 0.038056 | 138 | 414 | 13 | 161.877338 |
| Min Ribo P value | 8.194E-08 |
| Min TIS P value | None |
| Ribo-seq ID | Cell or Tissue | Phenotype | Ribo-seq Source Details | PMID |
|---|
| GSE119615_1_alt | Non-differentiated SH-SY5Y cells | Neuroblastoma | GSM3378857; GSM3378858; GSM3378859; GSM3378860 | 31109297; |
| GSE45833_3 | BJ cells | Pre-senescence | GSM1047588 | 23594524; |
| GSE45833_5 | BJ cells | Senescence | GSM1047590 | 23594524; |
| SRR6838651 | MCF7 | Breast adenocarcinoma | GSM3042964 | 30102689; |
| SRR6838651_alt | MCF7 | Breast adenocarcinoma | GSM3042964 | 30102689; |
Mass Spectrometry Information
Function and Disease
| Functional domain prediction |  |
| Analysis | Signature Accession | Signature Description | Start location | Stop location | Score | Status of the match | InterPro accession | InterPro description | GO | Pathways |
|---|
| Gene3D | G3DSA:1.25.40.10 | | 1 | 29 | 2.4E-5 | T | IPR011990 | Tetratricopeptide-like helical domain superfamily | GO:0005515 | |
| Gene3D | G3DSA:1.10.260.100 | | 30 | 80 | 2.3E-15 | T | | | | |
| PANTHER | PTHR22904 | | 1 | 76 | 1.2E-47 | T | | | | |
| Pfam | PF17830 | STI1 domain | 36 | 75 | 7.1E-14 | T | IPR041243 | STI1 domain | | |
| PANTHER | PTHR22904:SF517 | | 1 | 76 | 1.2E-47 | T | | | | |
| Disease | Detected |
|---|
| No results |
Related Variants
| Variant ID | Consequence to sORF | rsID | Ribo-seq ID |
|---|
| 11-64203623-G-A | Synonymous p.E73E | . | SRR5239056; SRR3680966; SRR3680967; SRR810103; SRR810104 |
| 11-64203624-T-C | Non-Synonymous p.Y74H | . | SRR5239056; SRR3680966; SRR3680967; SRR810103; SRR810104 |
Related Small Proteins with Different TISs
| SmProt ID | Small Protein Length | Start Codon | Strand | Blocks |
|---|
| SPROHSA320601 | 54 | GTG | + | 64203515-64203680 |
| SPROHSA26998 | 97 | AAG | + | 64203165-64203228, 64203449-64203680 |
| SPROHSA142288 | 98 | ATG | + | 64203162-64203228, 64203449-64203680 |
SmProt