Specific Information of Small Protein : SPROHSA136191
General Information
| Small Protein ID | SPROHSA136191 | ||
| Organism | human (Homo sapiens) | ||
| Small Protein Sequence | MKKRRNNGRTKKGRGHVQPICDTNCAQCVPKDKAINKFIIGNTVEAAAVRDISEASVFDAYVLPKLYLKLHYCLSCAIHSKVVRNRSCEAHKD* | ||
| RNA Sequence | ATGAAAAAAAGAAGGAACAACGGTCGTACCAAAAAGGGCCGCGGCCACGTGCAGCCTATTTGCGACACGAACTGTGCCCAATGTGTGCCCAAGGACAAGGCTATTAACAAATTCATCATTGGAAACACAGTGGAGGCTGCAGCAGTCAGGGACATTTCTGAAGCGAGCGTCTTTGATGCCTATGTGCTTCCCAAGCTGTATTTGAAGCTACATTACTGTCTGAGTTGTGCAATTCACAGCAAAGTAGTCAGGAATCGATCTTGTGAAGCCCACAAGGACTGA | ||
| Protein Length | 93 | ||
| Start Codon | ATG | ||
| Location | chr9:95123523-95123805:+ | ||
| Blocks | 95123523-95123805 | ||
| Mean PhyloCSF | 0 | ||
| Data Source | Ribosome profiling; | ||
| Related Genes | ENSG00000158169; FANCC; ENSG00000223849; AL354893.1; NONHSAG052920;NONHSAG101513; | ||
Ribosome profiling
| RiboID | GeneID | TransID | Symbol | GeneType | TISType | RiboPvalue | TISPvalue | StartOnTrans | StopOnTrans |
|---|---|---|---|---|---|---|---|---|---|
| GSE94454 | ENSG00000223849.1 | ENST00000433735.1 | AL354893.1 | processed_pseudogene | Novel | 0.016816 | None | 3 | 285 |
| SRR5350740 | ENSG00000223849.1 | ENST00000433735.1 | AL354893.1 | processed_pseudogene | Novel | 0.036248 | None | 3 | 285 |
| GSE83493 | ENSG00000223849.1 | ENST00000433735.1 | AL354893.1 | processed_pseudogene | Novel | 0.046958 | None | 3 | 285 |
| Min Ribo Pvalue | 0.016816 |
| Min TIS Pvalue | None |
Database information
| No results |
Literature information
| No results |
Mass Spectrometry Information
| No results |
Function and Disease
| Functional domain prediction |  |
| Analysis | Signature Accession | Signature Description | Start location | Stop location | Score | Status of the match | InterPro accession | InterPro description | GO | Pathways |
|---|---|---|---|---|---|---|---|---|---|---|
| No results | ||||||||||
| Disease | Detected | |
|---|---|---|
| No results | ||
Related Variants
| VarID | Consequence To sORF | rsID | RiboID |
|---|---|---|---|
| No results | |||
Related Small Proteins with Different TISs
| ID | Small Protein Length | Start Codon | Strand | Blocks |
|---|---|---|---|---|
| SPROHSA310089 | 28 | CTG | + | 95123718-95123805 |
| SPROHSA338823 | 32 | GTG | + | 95123706-95123805 |
| SPROHSA246762 | 42 | ATT | + | 95123676-95123805 |
References
| PMID | 28323820 |
| Title | Selective stalling of human translation through small-molecule engagement of the ribosome nascent chain |
| Journal | PLoS Biol.2017 Mar 21;15(3):e2001882.doi: 10.1371/journal.pbio.2001882.eCollection 2017 Mar. |
| Authors | Nathanael G Lintner,Kim F McClure,Donna Petersen,Allyn T Londregan,David W Piotrowski,Liuqing Wei,Jun Xiao,Michael Bolt,Paula M Loria,Bruce Maguire,Kieran F Geoghegan,Austin Huang,Tim Rolph,Spiros Liras,Jennifer A Doudna,Robert G Dullea,Jamie H D Cate |
| PMID | 28388414 |
| Title | Transcription Impacts the Efficiency of mRNA Translation via Co-transcriptional N6-adenosine Methylation |
| Journal | Cell.2017 Apr 6;169(2):326-337.e12.doi: 10.1016/j.cell.2017.03.031. |
| Authors | Boris Slobodin,Ruiqi Han,Vittorio Calderone,Joachim A F Oude Vrielink,Fabricio Loayza-Puch,Ran Elkon,Reuven Agami |
| PMID | 28460002 |
| Title | Proteomic analysis of polyribosomes identifies splicing factors as potential regulators of translation during mitosis |
| Journal | Nucleic Acids Res.2017 Jun 2;45(10):5945-5957.doi: 10.1093/nar/gkx326. |
| Authors | Ranen Aviner,Sarah Hofmann,Tamar Elman,Anjana Shenoy,Tamar Geiger,Ran Elkon,Marcelo Ehrlich,Orna Elroy-Stein |