Here we present NyuWa_10K_T2T haplotype panel, which is the largest and most comprehensive reference panel currently built on the T2T genome. The panel has 18,832 haplotypes (9,416 unrelated individuals) and multiple variant types including 84M SNPs/InDels, 1.05M TRVs, 44k MEVs, and 104k SVs. This resource enables us to explore the population structure and facilitate further genetic studies in populations around the world.

*required information

Before submitting, you need to choose the pipeline for your imputation and phasing job. When the data is processed, you can query status of it in the status page and download the imputed/phased data. For the data safety, only you have signed in to the web server can you upload your data. So please sign in first.

Notice: the job begins about three minute after the file is uploaded, so you need to query at least three minute later.

Choose the pipeline:*

phasing with Eagle v2.4.1 and impute with Beagle v5.4

phasing with Eagle v2.4.1, no imputation

imputing with Beagle v5.4, no phasing

Choose the reference panel:*

NyuWa 10k T2T


Upload your vcf file in T2T-CHM13:*
Or in GRCh38 (hg38), liftover by the server:


Test data: test_t2t_chr21.vcf.gz