SmProt

Specific Information of Small Protein : SPROMMU86568

General Information

Small Protein ID	SPROMMU86568
Organism	Mouse (Mus musculus)
Small Protein Sequence	MNADMDAVDAENQVELEEKTRLINQVLELQHTLEDLSARVDAVKEENLKLKSENQVLGQYIENLMSASSVFQTTDTKSKRK*
RNA Sequence	ATGAATGCTGACATGGACGCAGTTGATGCTGAAAATCAGGTGGAACTGGAAGAAAAGACTCGACTTATTAATCAGGTGTTGGAACTCCAACACACACTTGAAGATCTTTCTGCAAGAGTAGATGCAGTTAAGGAAGAAAATCTGAAGCTAAAGTCGGAAAATCAAGTTCTCGGACAATATATAGAAAACCTCATGTCTGCTTCTAGTGTTTTTCAAACAACTGATACAAAAAGCAAAAGGAAGTAA
Protein Length	81
Start Codon	ATG
Location	chr8:83435897-83438003:-
Blocks	83435897-83436040,83437552-83437636,83437984-83438003
Mean PhyloCSF	-6.6344715696
Data Source	Ribosome profiling;
Related Genes	ENSMUSG00000063253; Scoc;
Mass (Da)	mono. 9217.6; avg. 9223.2

Ribosome profiling

Ribo-seq ID	Ensembl Gene ID	Ensembl Transcript ID	Symbol	Gene Type	TIS Type	Ribo P value	TIS P value	Start On Trans	Stop On Trans	In-frame Count	Ribo-seq RPKM
GSE84112_1	ENSMUSG00000063253.11	ENSMUST00000212905.1	Scoc	Protein_coding	Truncated	0.009898	None	124	370	36	10.4688496
GSE84112_1_alt	ENSMUSG00000063253.11	ENSMUST00000212905.1	Scoc	Protein_coding	Truncated	0.009898	None	124	370	36	10.4688496
GSE60095	ENSMUSG00000063253.11	ENSMUST00000212905.1	Scoc	Protein_coding	Truncated	0.000212	None	124	370	342	47.4693769
GSE106386	ENSMUSG00000063253.11	ENSMUST00000212905.1	Scoc	Protein_coding	Truncated	2.458E-11	None	124	370	42	92.3616981
GSE22004	ENSMUSG00000063253.11	ENSMUST00000212905.1	Scoc	Protein_coding	Truncated	0.007861	None	124	370	9	7.38517333
GSE22004_alt	ENSMUSG00000063253.11	ENSMUST00000212905.1	Scoc	Protein_coding	Truncated	0.007861	None	124	370	9	7.38517333
GSE103667	ENSMUSG00000063253.11	ENSMUST00000212905.1	Scoc	Protein_coding	Truncated	3.574E-10	None	124	370	163	82.8453657
GSE51424	ENSMUSG00000063253.11	ENSMUST00000212905.1	Scoc	Protein_coding	Truncated	2.524E-09	None	124	370	279	118.057087
GSE69699	ENSMUSG00000063253.11	ENSMUST00000212905.1	Scoc	Protein_coding	Truncated	0.011747	None	124	370	4	30.9674913
GSE69699_alt	ENSMUSG00000063253.11	ENSMUST00000212905.1	Scoc	Protein_coding	Truncated	0.011747	None	124	370	4	30.9674913
GSE99585	ENSMUSG00000063253.11	ENSMUST00000212905.1	Scoc	Protein_coding	Truncated	0.000337	None	124	370	237	23.1592611
GSE99585_alt	ENSMUSG00000063253.11	ENSMUST00000212905.1	Scoc	Protein_coding	Truncated	0.000337	None	124	370	237	23.1592611
SRR618774,618775	ENSMUSG00000063253.11	ENSMUST00000212905.1	Scoc	Protein_coding	Truncated	6.398E-05	0.000115	124	370	19	50.8356500
GSE89011	ENSMUSG00000063253.11	ENSMUST00000212905.1	Scoc	Protein_coding	Truncated	1.047E-09	None	124	370	284	51.7161584
GSE102354	ENSMUSG00000063253.11	ENSMUST00000212905.1	Scoc	Protein_coding	Truncated	0.014715	None	124	370	26	112.597806
GSE84112_1	ENSMUSG00000063253.11	ENSMUST00000212031.1	Scoc	Protein_coding	Truncated	0.009898	None	137	383	36	10.4688496
GSE84112_1_alt	ENSMUSG00000063253.11	ENSMUST00000212031.1	Scoc	Protein_coding	Truncated	0.009898	None	137	383	36	10.4688496
GSE60095	ENSMUSG00000063253.11	ENSMUST00000212031.1	Scoc	Protein_coding	Truncated	0.000212	None	137	383	342	47.4693769
GSE106386	ENSMUSG00000063253.11	ENSMUST00000212031.1	Scoc	Protein_coding	Truncated	2.458E-11	None	137	383	42	92.3616981
GSE22004	ENSMUSG00000063253.11	ENSMUST00000212031.1	Scoc	Protein_coding	Truncated	0.007861	None	137	383	9	7.38517333
GSE22004_alt	ENSMUSG00000063253.11	ENSMUST00000212031.1	Scoc	Protein_coding	Truncated	0.007861	None	137	383	9	7.38517333
GSE103667	ENSMUSG00000063253.11	ENSMUST00000212031.1	Scoc	Protein_coding	Truncated	3.574E-10	None	137	383	163	82.8453657
GSE51424	ENSMUSG00000063253.11	ENSMUST00000212031.1	Scoc	Protein_coding	Truncated	2.524E-09	None	137	383	279	118.057087
GSE69699	ENSMUSG00000063253.11	ENSMUST00000212031.1	Scoc	Protein_coding	Truncated	0.011747	None	137	383	4	30.9674913
GSE69699_alt	ENSMUSG00000063253.11	ENSMUST00000212031.1	Scoc	Protein_coding	Truncated	0.011747	None	137	383	4	30.9674913
GSE99585	ENSMUSG00000063253.11	ENSMUST00000212031.1	Scoc	Protein_coding	Truncated	0.000337	None	137	383	237	23.1592611
GSE99585_alt	ENSMUSG00000063253.11	ENSMUST00000212031.1	Scoc	Protein_coding	Truncated	0.000337	None	137	383	237	23.1592611
SRR618774,618775	ENSMUSG00000063253.11	ENSMUST00000212031.1	Scoc	Protein_coding	Truncated	6.398E-05	0.006904	137	383	19	50.8356500
GSE89011	ENSMUSG00000063253.11	ENSMUST00000212031.1	Scoc	Protein_coding	Truncated	1.047E-09	None	137	383	284	51.7161584
GSE102354	ENSMUSG00000063253.11	ENSMUST00000212031.1	Scoc	Protein_coding	Truncated	0.014715	None	137	383	26	112.597806
GSE84112_1	ENSMUSG00000063253.11	ENSMUST00000081506.10	Scoc	Protein_coding	Truncated	0.009898	None	142	388	36	10.4688496
GSE84112_1_alt	ENSMUSG00000063253.11	ENSMUST00000081506.10	Scoc	Protein_coding	Truncated	0.009898	None	142	388	36	10.4688496
GSE60095	ENSMUSG00000063253.11	ENSMUST00000081506.10	Scoc	Protein_coding	Truncated	0.000212	None	142	388	342	47.4693769
GSE106386	ENSMUSG00000063253.11	ENSMUST00000081506.10	Scoc	Protein_coding	Truncated	2.458E-11	None	142	388	42	92.3616981
GSE22004	ENSMUSG00000063253.11	ENSMUST00000081506.10	Scoc	Protein_coding	Truncated	0.007861	None	142	388	9	7.38517333
GSE22004_alt	ENSMUSG00000063253.11	ENSMUST00000081506.10	Scoc	Protein_coding	Truncated	0.007861	None	142	388	9	7.38517333
GSE103667	ENSMUSG00000063253.11	ENSMUST00000081506.10	Scoc	Protein_coding	Truncated	3.574E-10	None	142	388	163	82.8453657
GSE51424	ENSMUSG00000063253.11	ENSMUST00000081506.10	Scoc	Protein_coding	Truncated	2.524E-09	None	142	388	279	118.057087
GSE69699	ENSMUSG00000063253.11	ENSMUST00000081506.10	Scoc	Protein_coding	Truncated	0.011747	None	142	388	4	30.9674913
GSE69699_alt	ENSMUSG00000063253.11	ENSMUST00000081506.10	Scoc	Protein_coding	Truncated	0.011747	None	142	388	4	30.9674913
GSE99585	ENSMUSG00000063253.11	ENSMUST00000081506.10	Scoc	Protein_coding	Truncated	0.000337	None	142	388	237	23.1592611
GSE99585_alt	ENSMUSG00000063253.11	ENSMUST00000081506.10	Scoc	Protein_coding	Truncated	0.000337	None	142	388	237	23.1592611
SRR618774,618775	ENSMUSG00000063253.11	ENSMUST00000081506.10	Scoc	Protein_coding	Truncated	6.398E-05	7.711E-06	142	388	19	50.8356500
GSE89011	ENSMUSG00000063253.11	ENSMUST00000081506.10	Scoc	Protein_coding	Truncated	1.047E-09	None	142	388	284	51.7161584
GSE102354	ENSMUSG00000063253.11	ENSMUST00000081506.10	Scoc	Protein_coding	Truncated	0.014715	None	142	388	26	112.597806

Min Ribo P value	2.458E-11
Min TIS P value	7.711E-06

Ribo-seq ID	Cell or Tissue	Phenotype	Ribo-seq Source Details	PMID
GSE102354	Heterozygos Taiwanese mice (Smn+/-; SMN2tg/0) brain	WT	GSM2735372; GSM2735373	30355487;
GSE103667	NIH3T3	WT	GSM2778762; GSM2778763	29576526;
GSE106386	ES cell derived neurons E14Tg2A.4	WT	GSM2836997	30349096;
GSE22004	C57BL/6-Neutrophils cultured from bone marrow	WT	GSM546987	20703300;
GSE22004_alt	C57BL/6-Neutrophils cultured from bone marrow	WT	GSM546987	20703300;
GSE51424	brain	WT	GSM1245214; GSM1245215; GSM1245216	25122893;
GSE60095	ES cell	WT	GSM1464901	25159147;
GSE69699	C57BL/6-gastrocnemius	WT	GSM1707652; GSM1707653	26845575;
GSE69699_alt	C57BL/6-gastrocnemius	WT	GSM1707652; GSM1707653	26845575;
GSE84112_1	ROSA26mT/mG 5-8 weeks liver	WT	GSM2227367; GSM2227368	27956496;
GSE84112_1_alt	ROSA26mT/mG 5-8 weeks liver	WT	GSM2227367; GSM2227368	27956496;
GSE89011	RF8-embryonic stem cell	WT	GSM2357212; GSM2357214	28003464;
GSE99585	C57BL/6-Quadriceps muscle	WT	GSM2648077; GSM2648078	28615380;
GSE99585_alt	C57BL/6-Quadriceps muscle	WT	GSM2648077; GSM2648078	28615380;
SRR618774,618775	MEF	WT	SRR618774; SRR618775	22927429;

Database information

No results

Literature information

No results

Mass Spectrometry Information

No results

Function and Disease

Functional domain prediction

Analysis	Signature Accession	Signature Description	Start location	Stop location	Score	Status of the match	InterPro accession	InterPro description	Pathways
Gene3D	G3DSA:1.20.5.170		1	81	8.2E-44	T
Pfam	PF10224	Short coiled-coil protein	2	75	3.5E-28	T	IPR019357	Short coiled-coil protein	Reactome: R-HSA-6811440
PANTHER	PTHR21614		1	81	1.1E-43	T	IPR019357	Short coiled-coil protein	Reactome: R-HSA-6811440
Coils	Coil		19	53	-	T

Related Small Proteins with Different TISs

SmProt ID	Small Protein Length	Start Codon	Strand	Blocks
SPROMMU96746	82	ATG	-	83435897-83436040, 83437552-83437636, 83437984-83438006
SPROMMU172224	86	CTG	-	83435897-83436040, 83437552-83437636, 83437984-83438018

a reliable repository with comprehensive annotation of small proteins derived from ribosome profiling