Specific Information of Small Protein : SPROMMU172224
General Information
| Small Protein ID | SPROMMU172224 |
| Organism | Mouse (Mus musculus) |
| Small Protein Sequence | LLPKMMNADMDAVDAENQVELEEKTRLINQVLELQHTLEDLSARVDAVKEENLKLKSENQVLGQYIENLMSASSVFQTTDTKSKRK* |
| RNA Sequence | CTGCTACCCAAGATGATGAATGCTGACATGGACGCAGTTGATGCTGAAAATCAGGTGGAACTGGAAGAAAAGACTCGACTTATTAATCAGGTGTTGGAACTCCAACACACACTTGAAGATCTTTCTGCAAGAGTAGATGCAGTTAAGGAAGAAAATCTGAAGCTAAAGTCGGAAAATCAAGTTCTCGGACAATATATAGAAAACCTCATGTCTGCTTCTAGTGTTTTTCAAACAACTGATACAAAAAGCAAAAGGAAGTAA |
| Protein Length | 86 |
| Start Codon | CTG |
| Location | chr8:83435897-83438018:- |
| Blocks | 83435897-83436040,83437552-83437636,83437984-83438018 |
| Mean PhyloCSF | -6.58968967862 |
| Data Source | Ribosome profiling; |
| Related Genes | ENSMUSG00000063253; Scoc; |
| Mass (Da) | mono. 9800; avg. 9806 |
Ribosome profiling
| Ribo-seq ID | Ensembl Gene ID | Ensembl Transcript ID | Symbol | Gene Type | TIS Type | Ribo P value | TIS P value | Start On Trans | Stop On Trans | In-frame Count | Ribo-seq RPKM |
|---|
| GSE84112_2_alt | ENSMUSG00000063253.11 | ENSMUST00000081506.10 | Scoc | Protein_coding | Truncated | 8.831E-05 | None | 127 | 388 | 42 | 14.5567918 |
| GSE105147_2_alt | ENSMUSG00000063253.11 | ENSMUST00000081506.10 | Scoc | Protein_coding | Truncated | 0.008924 | None | 127 | 388 | 14 | 5.73094450 |
| GSE106386_alt | ENSMUSG00000063253.11 | ENSMUST00000081506.10 | Scoc | Protein_coding | Truncated | 1.305E-11 | None | 127 | 388 | 44 | 91.1989619 |
| GSE102659_1_alt | ENSMUSG00000063253.11 | ENSMUST00000081506.10 | Scoc | Protein_coding | Truncated | 0.000716 | None | 127 | 388 | 15 | 12.0535369 |
| GSE102659_2_alt | ENSMUSG00000063253.11 | ENSMUST00000081506.10 | Scoc | Protein_coding | Truncated | 0.002724 | None | 127 | 388 | 14 | 11.1787572 |
| GSE103667_alt | ENSMUSG00000063253.11 | ENSMUST00000081506.10 | Scoc | Protein_coding | Truncated | 1.678E-10 | None | 127 | 388 | 220 | 105.389633 |
| GSE51424_alt | ENSMUSG00000063253.11 | ENSMUST00000081506.10 | Scoc | Protein_coding | Truncated | 1.154E-09 | None | 127 | 388 | 317 | 126.427550 |
| GSE83823_alt | ENSMUSG00000063253.11 | ENSMUST00000081506.10 | Scoc | Protein_coding | Truncated | 0.000588 | None | 127 | 388 | 20 | 49.9066728 |
| SRR618774,618775 | ENSMUSG00000063253.11 | ENSMUST00000081506.10 | Scoc | Protein_coding | Truncated | 1.992E-05 | 0.000522 | 127 | 388 | 29 | 73.1319878 |
| GSE89011_alt | ENSMUSG00000063253.11 | ENSMUST00000081506.10 | Scoc | Protein_coding | Truncated | 6.713E-10 | None | 127 | 388 | 350 | 60.0717883 |
| GSE102354_alt | ENSMUSG00000063253.11 | ENSMUST00000081506.10 | Scoc | Protein_coding | Truncated | 0.00572 | None | 127 | 388 | 32 | 130.617437 |
| Min Ribo P value | 1.305E-11 |
| Min TIS P value | None |
| Ribo-seq ID | Cell or Tissue | Phenotype | Ribo-seq Source Details | PMID |
|---|
| GSE102354_alt | Heterozygos Taiwanese mice (Smn+/-; SMN2tg/0) brain | WT | GSM2735372; GSM2735373 | 30355487; |
| GSE102659_1_alt | C57BL/6-liver | WT-normal | GSM2742565 | 29429926; |
| GSE102659_2_alt | C57BL/6-liver | WT-fasting | GSM2742567 | 29429926; |
| GSE103667_alt | NIH3T3 | WT | GSM2778762; GSM2778763 | 29576526; |
| GSE105147_2_alt | C57BL/6-specific expression of LSL-KRAS(G12D) | Liver tumour | GSM2823261; GSM2823262 | 30643286; |
| GSE106386_alt | ES cell derived neurons E14Tg2A.4 | WT | GSM2836997 | 30349096; |
| GSE51424_alt | brain | WT | GSM1245214; GSM1245215; GSM1245216 | 25122893; |
| GSE83823_alt | C57BL/6-fetal liver-Erythroid progenitors | WT | GSM2219142 | 27899360; |
| GSE84112_2_alt | ROSA26mT/mG 5-8 weeks liver | WT | GSM2227371; GSM2227372; GSM2227373 | NA; |
| GSE89011_alt | RF8-embryonic stem cell | WT | GSM2357212; GSM2357214 | 28003464; |
| SRR618774,618775 | MEF | WT | SRR618774; SRR618775 | 22927429; |
Mass Spectrometry Information
Function and Disease
| Functional domain prediction |  |
| Analysis | Signature Accession | Signature Description | Start location | Stop location | Score | Status of the match | InterPro accession | InterPro description | GO | Pathways |
|---|
| Gene3D | G3DSA:1.20.5.170 | | 5 | 86 | 3.0E-44 | T | | | | |
| Coils | Coil | | 24 | 58 | - | T | | | | |
| PANTHER | PTHR21614 | | 3 | 86 | 2.2E-45 | T | IPR019357 | Short coiled-coil protein | | Reactome: R-HSA-6811440 |
| Pfam | PF10224 | Short coiled-coil protein | 7 | 80 | 4.4E-28 | T | IPR019357 | Short coiled-coil protein | | Reactome: R-HSA-6811440 |
Related Small Proteins with Different TISs
| SmProt ID | Small Protein Length | Start Codon | Strand | Blocks |
|---|
| SPROMMU86568 | 81 | ATG | - | 83435897-83436040, 83437552-83437636, 83437984-83438003 |
| SPROMMU96746 | 82 | ATG | - | 83435897-83436040, 83437552-83437636, 83437984-83438006 |
SmProt