Specific Information of Small Protein : SPROHSA719
General Information
| Small Protein ID | SPROHSA719 |
| Organism | Human (Homo sapiens) |
| Small Protein Sequence | KKHFNYNKIVEHQNLSKKKKKKKKQLMKKKKLLEDDFEVNVSNAWFQAMYTSHLFNVHPSDPNFKKTKAVEKTLEEKAWQREQKKQELTQAIKKKEGQ* |
| RNA Sequence | AAGAAACACTTCAATTACAACAAGATTGTGGAGCACCAGAACCTGAGCaaaaagaagaaaaagaagaaaaagcagctcatgaaaaaaaagaaATTATTAGAGGATGACTTTGAGGTAAATGTTAGCAATGCATGGTTTCAAGCAATGTACACTTCCCACTTGTTCAATGTGCATCCCTCAGATCCCAATTTCAAGAAAACAAAAGCTGTGGAAAAAACCCTTGAGGAGAAAGCCTGGCAAAGAGAACAGAAAAAACAAGAACTTACTCAGGCAATAAAGAAAAAAGAGggccagTGA |
| Protein Length | 98 |
| Start Codon | AAG |
| Location | chr8:53973604-53974132:+ |
| Blocks | 53973604-53973898,53974129-53974132 |
| Mean PhyloCSF | 0 |
| Data Source | Ribosome profiling; |
| Related Genes | ENSG00000187735; TCEA1; ENSG00000253667; AC100821.1; |
| Mass (Da) | mono. 11821.4; avg. 11828.6 |
Ribosome profiling
| Ribo-seq ID | Ensembl Gene ID | Ensembl Transcript ID | Symbol | Gene Type | TIS Type | Ribo P value | TIS P value | Start On Trans | Stop On Trans | In-frame Count | Ribo-seq RPKM |
|---|
| GSE105082_alt | ENSG00000253667.2 | ENST00000523153.2 | AC100821.1 | Processed_pseudogene | Novel | 0.045514 | None | 2104 | 2401 | 11 | 2.51684546 |
| GSE65778 | ENSG00000253667.2 | ENST00000523153.2 | AC100821.1 | Processed_pseudogene | Novel | 0.036288 | None | 2104 | 2401 | 3 | 1.77131491 |
| GSE94454_alt | ENSG00000253667.2 | ENST00000523153.2 | AC100821.1 | Processed_pseudogene | Novel | 0.000736 | None | 2104 | 2401 | 43 | 6.44503217 |
| Min Ribo P value | 0.000736 |
| Min TIS P value | None |
| Ribo-seq ID | Cell or Tissue | Phenotype | Ribo-seq Source Details | PMID |
|---|
| GSE105082_alt | HELA | Cervical cancer | GSM2817679; GSM2817680 | 30591072; |
| GSE65778 | HEK293T | WT | GSM1606107; GSM1606108 | 25719440; |
| GSE94454_alt | Huh7 | Hepatoma | GSM2476003; GSM2476004; GSM2476005 | 28323820; |
Mass Spectrometry Information
Function and Disease
| Functional domain prediction |  |
| Analysis | Signature Accession | Signature Description | Start location | Stop location | Score | Status of the match | InterPro accession | InterPro description | GO | Pathways |
|---|
| PANTHER | PTHR12202 | | 2 | 95 | 9.1E-20 | T | IPR039754 | Pre-rRNA-processing protein Esf1 | GO:0006364 | |
| Coils | Coil | | 9 | 36 | - | T | | | | |
| Pfam | PF08159 | NUC153 domain | 46 | 70 | 5.6E-8 | T | IPR012580 | NUC153 | GO:0005634 | |
| Disease | Detected |
|---|
| No results |
Related Variants
| Variant ID | Consequence to sORF | rsID | Ribo-seq ID |
|---|
| 8-53973701-T-A | Non-Synonymous p.L33I | . | SRR5382423; SRR6053333; SRR1333393; SRR1795425 |
Related Small Proteins with Different TISs
| SmProt ID | Small Protein Length | Start Codon | Strand | Blocks |
|---|
| SPROHSA136184 | 72 | atg | + | 53973682-53973898, 53974129-53974132 |
| SPROHSA244265 | 90 | ATT | + | 53973628-53973898, 53974129-53974132 |
| SPROHSA14000 | 91 | AAG | + | 53973625-53973898, 53974129-53974132 |
SmProt