Specific Information of Small Protein : SPROHSA136184
General Information
Small Protein IDSPROHSA136184
Organismhuman (Homo sapiens)
Small Protein SequenceMKKKKLLEDDFEVNVSNAWFQAMYTSHLFNVHPSDPNFKKTKAVEKTLEEKAWQREQKKQELTQAIKKKEGQ*
RNA SequenceatgaaaaaaaagaaATTATTAGAGGATGACTTTGAGGTAAATGTTAGCAATGCATGGTTTCAAGCAATGTACACTTCCCACTTGTTCAATGTGCATCCCTCAGATCCCAATTTCAAGAAAACAAAAGCTGTGGAAAAAACCCTTGAGGAGAAAGCCTGGCAAAGAGAACAGAAAAAACAAGAACTTACTCAGGCAATAAAGAAAAAAGAGggccagTGA
Protein Length72
Start Codonatg
Locationchr8:53973682-53974132:+
Blocks53973682-53973898,53974129-53974132
Mean PhyloCSF0
Data SourceRibosome profiling;
Related GenesENSG00000187735; TCEA1; ENSG00000253667; AC100821.1;
Ribosome profiling
RiboIDGeneIDTransIDSymbolGeneTypeTISTypeRiboPvalueTISPvalueStartOnTransStopOnTrans
GSE94454ENSG00000253667.2ENST00000523153.2AC100821.1processed_pseudogeneNovel0.029625None21822401
Min Ribo Pvalue0.029625
Min TIS PvalueNone
RiboIDCellORTissuePhenotypeRiboSourcePMID
GSE94454Huh7hepatomaGSM2476003;GSM2476004;GSM247600528323820;

Database information
No results
Literature information
No results
Mass Spectrometry Information
No results
Function and Disease
Functional domain prediction Funtion   
AnalysisSignature AccessionSignature DescriptionStart locationStop locationScoreStatus of the matchInterPro accessionInterPro descriptionGOPathways
No results
DiseaseDetected
No results
Related Variants
VarIDConsequence To sORFrsIDRiboID
8-53973701-T-ANon-Synonymous p.L7I.SRR5382423;SRR6053333;SRR1333393;SRR1795425
Related Small Proteins with Different TISs
IDSmall Protein LengthStart CodonStrandBlocks
SPROHSA24426590ATT+53973628-53973898,53974129-53974132
SPROHSA1400091AAG+53973625-53973898,53974129-53974132
SPROHSA71998AAG+53973604-53973898,53974129-53974132
References
PMID28323820
TitleSelective stalling of human translation through small-molecule engagement of the ribosome nascent chain
JournalPLoS Biol.2017 Mar 21;15(3):e2001882.doi: 10.1371/journal.pbio.2001882.eCollection 2017 Mar.
AuthorsNathanael G Lintner,Kim F McClure,Donna Petersen,Allyn T Londregan,David W Piotrowski,Liuqing Wei,Jun Xiao,Michael Bolt,Paula M Loria,Bruce Maguire,Kieran F Geoghegan,Austin Huang,Tim Rolph,Spiros Liras,Jennifer A Doudna,Robert G Dullea,Jamie H D Cate