SmProt

Specific Information of Small Protein : SPROHSA200502

General Information

Small Protein ID	SPROHSA200502
Organism	Human (Homo sapiens)
Small Protein Sequence	MGKLSRCSSLRNLDLRSVCGTSIKMIYGNKI*
RNA Sequence	ATGGGAAAATTAAGCAGATGCTCCAGTTTGAGAAACCTGGATCTGCGATCTGTTTGTGGTACCAGCATCAAGATGATTTATGGTAATAAGATATAA
Protein Length	31
Start Codon	ATG
Location	chr14:58267387-58291692:-
Blocks	58267387-58267393,58273978-58274010,58291634-58291692
Mean PhyloCSF	-8.33048959325
Data Source	Ribosome profiling; Literature;
Related Genes	ENSG00000139971; ARMH4; ENSG00000100567; PSMA3; ENSG00000258682; AL132989.1; ENSG00000257621; PSMA3-AS1; ENSG00000180189; HMGB1P14; ENSG00000279636; AL132989.2; NONHSAG015097;NONHSAG015106;NONHSAG015108;NONHSAG068810;
Mass (Da)	mono. 3442.8; avg. 3445.1

Ribosome profiling

Ribo-seq ID	Ensembl Gene ID	Ensembl Transcript ID	Symbol	Gene Type	TIS Type	Ribo P value	TIS P value	Start On Trans	Stop On Trans	In-frame Count	Ribo-seq RPKM
SRR5047770	ENSG00000257621.8	ENST00000556002.5	PSMA3-AS1	LncRNA	Novel	0.014247	None	163	259	25	20.6615089
SRR5047771	ENSG00000257621.8	ENST00000556002.5	PSMA3-AS1	LncRNA	Novel	0.025453	None	163	259	40	19.0550851
SRR7207252	ENSG00000257621.8	ENST00000556002.5	PSMA3-AS1	LncRNA	Novel	0.011775	None	163	259	19	52.3397845
SRR7207252_alt	ENSG00000257621.8	ENST00000556002.5	PSMA3-AS1	LncRNA	Novel	0.011775	None	163	259	19	52.3397845
SRR5350740	ENSG00000257621.8	ENST00000556002.5	PSMA3-AS1	LncRNA	Novel	0.033416	None	163	259	5	19.1411063
GSE83493	ENSG00000257621.8	ENST00000556002.5	PSMA3-AS1	LncRNA	Novel	0.011534	None	163	259	16	19.9734608
GSE83493_alt	ENSG00000257621.8	ENST00000556002.5	PSMA3-AS1	LncRNA	Novel	0.011534	None	163	259	16	19.9734608

Min Ribo P value	0.011534
Min TIS P value	None

Ribo-seq ID	Cell or Tissue	Phenotype	Ribo-seq Source Details	PMID
GSE83493	HeLa S3	Cervical cancer	GSM2204389; GSM2204390; GSM2204391; GSM2204392	28460002;
GSE83493_alt	HeLa S3	Cervical cancer	GSM2204389; GSM2204390; GSM2204391; GSM2204392	28460002;
SRR5047770	iPSC-differentiated dopamine neurons	Parkinson Disease	GSM2402496; GSM2402497; GSM2402498	NA;
SRR5047771	iPSC-differentiated dopamine neurons	Parkinson Disease	NA	NA;
SRR5350740	MCF7	Breast adenocarcinoma	GSM2538884	28388414;
SRR7207252	MCF10A-ER-Src	Breast adenocarcinoma	GSM3150265	30089253;
SRR7207252_alt	MCF10A-ER-Src	Breast adenocarcinoma	GSM3150265	30089253;

Database information

No results

Literature information

PMID	31155234;
Cell lines Or Tissues	left ventricle
Phenotype	WT
Gene ID	ENSG00000257621
Transcript ID	ENST00000556002
Symbol	NA
ORF Type	sORF
Gene Type	antisense
Throughput	High-throughput Literature Mining
Interaction	NA
Function Description	NA
PMID	26687005;
Cell lines Or Tissues	BJ
Phenotype	NULL
Gene ID	ENSG00000257621
Transcript ID	ENST00000556002
Symbol	NA
ORF Type	sORF
Gene Type	Antisense
Throughput	High-throughput Literature Mining
Interaction	NA
Function Description	NA

Mass Spectrometry Information

No results

Function and Disease

Functional domain prediction

Analysis	Signature Accession	Signature Description	Start location	Stop location	Score	Status of the match	InterPro accession	InterPro description	GO	Pathways
No results

Disease	Detected
No results

Related Variants

Variant ID	Consequence to sORF	rsID	Ribo-seq ID
No results

Related Small Proteins with Different TISs

SmProt ID	Small Protein Length	Start Codon	Strand	Blocks
SPROHSA160278	7	ATG	-	58267387-58267393, 58273978-58273996
SPROHSA370547	22	TTG	-	58267387-58267393, 58273978-58274010, 58291634-58291665
SPROHSA4968	37	AAG	-	58267387-58267393, 58273978-58274010, 58291634-58291707, 58297954-58297957