Specific Information of Small Protein : SPROHSA134337
General Information
| Small Protein ID | SPROHSA134337 |
| Organism | Human (Homo sapiens) |
| Small Protein Sequence | ICSSDKRIACEEEFSDSDEVREGGHKNSSNFKKAKRVKTGWKRERPR* |
| RNA Sequence | ATCTGTTCCTCTGACAAACGAATTGCCTGTGAGGAAGAGTTCTCTGACTCTGATGAGGTGAGAGAGGGTGGCCACAAGAACTCTTCCAACTTCAAAAAAGCCAAGAGAGTCAAAACAGGATGGAAAAGAGAAAGACCTAGATGA |
| Protein Length | 47 |
| Start Codon | ATC |
| Location | chr1:220627219-220627363:+ |
| Blocks | 220627219-220627363 |
| Mean PhyloCSF | -3.51116665949 |
| Data Source | Ribosome profiling; |
| Related Genes | ENSG00000116141; MARK1; ENSG00000233012; HDAC1P2; NONHSAG004352; |
| Mass (Da) | mono. 5479.7; avg. 5483 |
Ribosome profiling
| Ribo-seq ID | Ensembl Gene ID | Ensembl Transcript ID | Symbol | Gene Type | TIS Type | Ribo P value | TIS P value | Start On Trans | Stop On Trans | In-frame Count | Ribo-seq RPKM |
|---|
| SRR4045276_alt | ENSG00000233012.2 | ENST00000453661.1 | HDAC1P2 | Transcribed_processed_pseudogene | Novel | 0.003128 | None | 1169 | 1313 | 11 | 18.0920248 |
| GSE103308_alt | ENSG00000233012.2 | ENST00000453661.1 | HDAC1P2 | Transcribed_processed_pseudogene | Novel | 0.000257 | None | 1169 | 1313 | 50 | 30.8858725 |
| GSE105082_alt | ENSG00000233012.2 | ENST00000453661.1 | HDAC1P2 | Transcribed_processed_pseudogene | Novel | 0.012411 | None | 1169 | 1313 | 66 | 31.1459625 |
| GSE94454_alt | ENSG00000233012.2 | ENST00000453661.1 | HDAC1P2 | Transcribed_processed_pseudogene | Novel | 0.008106 | None | 1169 | 1313 | 66 | 20.4030233 |
| GSE104033_alt | ENSG00000233012.2 | ENST00000453661.1 | HDAC1P2 | Transcribed_processed_pseudogene | Novel | 0.025021 | None | 1169 | 1313 | 16 | 56.2065112 |
| SRR7207252_alt | ENSG00000233012.2 | ENST00000453661.1 | HDAC1P2 | Transcribed_processed_pseudogene | Novel | 0.005188 | None | 1169 | 1313 | 17 | 31.2202223 |
| SRR5350740_alt | ENSG00000233012.2 | ENST00000453661.1 | HDAC1P2 | Transcribed_processed_pseudogene | Novel | 0.010936 | None | 1169 | 1313 | 11 | 28.0736227 |
| GSE83493_alt | ENSG00000233012.2 | ENST00000453661.1 | HDAC1P2 | Transcribed_processed_pseudogene | Novel | 0.010936 | None | 1169 | 1313 | 7 | 5.82559275 |
| GSE97140_alt | ENSG00000233012.2 | ENST00000453661.1 | HDAC1P2 | Transcribed_processed_pseudogene | Novel | 0.049327 | None | 1169 | 1313 | 18 | 63.2249371 |
| Min Ribo P value | 0.000257 |
| Min TIS P value | None |
| Ribo-seq ID | Cell or Tissue | Phenotype | Ribo-seq Source Details | PMID |
|---|
| GSE103308_alt | RD-muscle | WT | GSM2760247 | 29696588; |
| GSE104033_alt | HAP-1 cells | Chronic myeloid leukemia | GSM2788007; GSM2788008 | 30143613; |
| GSE105082_alt | HELA | Cervical cancer | GSM2817679; GSM2817680 | 30591072; |
| GSE83493_alt | HeLa S3 | Cervical cancer | GSM2204389; GSM2204390; GSM2204391; GSM2204392 | 28460002; |
| GSE94454_alt | Huh7 | Hepatoma | GSM2476003; GSM2476004; GSM2476005 | 28323820; |
| GSE97140_alt | Flp-In T-REx-293 | WT | GSM2552194; GSM2552195 | 28520920; |
| SRR4045276_alt | Meg01 cells | WT | GSM2285909 | 27681415; |
| SRR5350740_alt | MCF7 | Breast adenocarcinoma | GSM2538884 | 28388414; |
| SRR7207252_alt | MCF10A-ER-Src | Breast adenocarcinoma | GSM3150265 | 30089253; |
Mass Spectrometry Information
Function and Disease
| Functional domain prediction |  |
| Analysis | Signature Accession | Signature Description | Start location | Stop location | Score | Status of the match | InterPro accession | InterPro description | GO | Pathways |
|---|
| MobiDBLite | mobidb-lite | consensus disorder prediction | 14 | 29 | - | T | | | | |
| MobiDBLite | mobidb-lite | consensus disorder prediction | 14 | 47 | - | T | | | | |
| Disease | Detected |
|---|
| No results |
Related Variants
| Variant ID | Consequence to sORF | rsID | Ribo-seq ID |
|---|
| 1-220627225-T-C | Synonymous p.C2C | . | SRR5239056 |
Related Small Proteins with Different TISs
| SmProt ID | Small Protein Length | Start Codon | Strand | Blocks |
|---|
| SPROHSA2844 | 22 | AAG | + | 220627294-220627363 |
| SPROHSA240468 | 40 | ATT | + | 220627240-220627363 |
SmProt