Detail Information of piRNA: piR-mmu-8676

Dataset	Accession	Reads	PubMed	Method	Tissue
4	N/A	N/A	16751776	small RNA	testis
6	GSM113695	34	16778019	Chromatography	testes tissue from Swiss Webster male mice, 8-10 weeks old
11	GSM822760	252	22121019	Miwi IP	Testes, C57BL/6 Adult Miwi +/+
12	GSM822758	94	22121019	Miwi IP	Testes, C57BL/6 P14 Miwi +/+
13	GSM822759	133	22121019	Miwi IP	Testes, C57BL/6 P20 Miwi +/+
14	GSM822761	113	22121019	Miwi IP	Testes, C57BL/6 Adult Miwi +/ADH
15	GSM822762	1	22121019	Miwi IP	Testes, C57BL/6 Adult Miwi -/ADH
16	GSM822763	2	22121019	Miwi IP	Testes, C57BL/6 Adult Miwi -/ADH
17	GSM822764	1	22121019	Miwi IP	Testes, C57BL/6 Adult Miwi -/ADH
31	GSM684624	610	22842725	Miwi CLIP	C57BL/6 adult testis
32	GSM684625	167	22842725	Miwi CLIP	C57BL/6 adult testis
33	GSM684626	41	22842725	Miwi CLIP	C57BL/6 adult testis
34	GSM684627	102	22842725	Miwi CLIP	C57BL/6 adult testis
51	GSM610966	6	21602304	small RNA	Male germ cell, Pachytene spermatocytes
52	GSM610967	54	21602304	small RNA	Male germ cell, Round spermatids
67	GSM509276	1	20439430	small RNA	MitoPLD-/- E16.5 testis
121	GSM545783	112	20534472	Mov10L1 IP	wild type adult testis
129	GSM466729	1	20059948	Mili IP	Tdrd9+/- 14dpp testis
132	GSM475279	2411	20022248	Miwi IP	adult testis
133	GSM475280	369	20022248	Mili IP	adult testis
217	GSM1653802	846	25582079	MIWI CLIP	round spermatids
225	GSM1528807	2881	26588211	small RNA	Adult testes Asb1 ao31(Het)
226	GSM1528808	3854	26588211	small RNA	Adult testes Asb1 ao32(KO)
227	GSM1528809	3000	26588211	small RNA	Adult testes Asb1 ao34(Het)
228	GSM1528810	1967	26588211	small RNA	Adult testes Asb1 ao36(KO)
234	GSM433288	257	26115953	small RNA	18dpp hetero tdrd6 KO testes
235	GSM433289	232	26115953	small RNA	18dpp homo tdrd6 KO testes
236	GSM433290	1551	26115953	small RNA	25dpp hetero tdrd6 KO testes
237	GSM433291	287	26115953	small RNA	25dpp homo tdrd6 KO testes
247	GSM1318060	1	25262350	small RNA	E16.5 whole testes Hsp90-alpha KO
345	GSM475279	2411	20022248	Miwi-IP	testis
346	GSM475280	369	20022248	Mili-IP	testis
347	GSM475281	511	20022248	small RNA	testis
348	GSM3772906	14	32674113	small RNA	E16.5 testes(mixed B6CBAF1/Crl and C57BL/6N; control)
352	GSM3772910	1	32674113	small RNA	E16.5 testes(mixed B6CBAF1/Crl and C57BL/6N; Spocd1-/-)
354	GSM4635227	1	33184219	small RNA	primordial germ cells(age: E13.5; sex: male)
441	GSM1096582	87	23523368	small RNA	Wild Type 10.5 dpp testes
443	GSM1096583	14	23523368	small RNA	Wild Type 12.5 dpp testes
445	GSM1096584	9	23523368	small RNA	Wild Type 14.5 dpp testes
446	GSM1096601	221	23523368	oxidized small RNA	Wild Type 14.5 dpp testes
447	GSM1096585	164	23523368	small RNA	Wild Type 17.5 dpp testes
448	GSM1096602	71	23523368	oxidized small RNA	Wild Type 17.5 dpp testes
449	GSM1096586	343	23523368	small RNA	Wild Type 20.5 dpp testes
450	GSM1096603	279	23523368	oxidized small RNA	Wild Type 20.5 dpp testes
451	GSM1096587	407	23523368	small RNA	Wild Type 6 weeks dpp testes
452	GSM1096604	256	23523368	oxidized small RNA	Wild Type 6 weeks dpp testes

1 best hit(s) with 0 mismatch(es) in GRCm38

No.	Location	Gene	RepeatMaker
Location 1	7:73121027-73121056:+		SINE Alu B1_Mus1;

PubMed	16751776	Journal	Nature. 2006 Jul 13;442(7099):199-202.
Title	A germline-specific class of small RNAs binds mammalian Piwi proteins
Authors	Girard A, Sachidanandam R, Hannon GJ, Carmell MA.

PubMed	16778019	Journal	Science. 2006 Jul 21;313(5785):363-7.
Title	Characterization of the piRNA complex from rat testes.
Authors	Lau NC, Seto AG, Kim J, Kuramochi-Miyagawa S, Nakano T, Bartel DP, Kingston RE.

PubMed	22121019	Journal	Nature. 2011 Nov 27;480(7376):264-7.
Title	Miwi catalysis is required for piRNA amplification-independent LINE1 transposon silencing.
Authors	Reuter M, Berninger P, Chuma S, Shah H, Hosokawa M, Funaya C, Antony C, Sachidanandam R, Pillai RS.

PubMed	22842725	Journal	Nat Struct Mol Biol. 2012 Aug;19(8):773-81.
Title	Mili and Miwi target RNA repertoire reveals piRNA biogenesis and function of Miwi in spermiogenesis.
Authors	Vourekas A, Zheng Q, Alexiou P, Maragkakis M, Kirino Y, Gregory BD, Mourelatos Z.

PubMed	21602304	Journal	RNA. 2011 Jul;17(7):1191-203.
Title	piRNA profiling during specific stages of mouse spermatogenesis.
Authors	Gan H, Lin X, Zhang Z, Zhang W, Liao S, Wang L, Han C.

PubMed	20439430	Journal	Genes Dev. 2010 May;24(9):887-92.
Title	MVH in piRNA processing and gene silencing of retrotransposons.
Authors	Kuramochi-Miyagawa S, Watanabe T, Gotoh K, Takamatsu K, Chuma S, Kojima-Kita K, Shiromoto Y, Asada N, Toyoda A, Fujiyama A, Totoki Y, Shibata T, Kimura T, Nakatsuji N, Noce T, Sasaki H, Nakano T.

PubMed	20534472	Journal	Proc Natl Acad Sci U S A. 2010 Jun 29;107(26):11841-6.
Title	Mouse MOV10L1 associates with Piwi proteins and is an essential component of the Piwi-interacting RNA (piRNA) pathway.
Authors	Zheng K, Xiol J, Reuter M, Eckardt S, Leu NA, McLaughlin KJ, Stark A, Sachidanandam R, Pillai RS, Wang PJ.

PubMed	20059948	Journal	Dev Cell. 2009 Dec;17(6):775-87.
Title	The TDRD9-MIWI2 complex is essential for piRNA-mediated retrotransposon silencing in the mouse male germline.
Authors	Shoji M, Tanaka T, Hosokawa M, Reuter M, Stark A, Kato Y, Kondoh G, Okawa K, Chujo T, Suzuki T, Hata K, Martin SL, Noce T, Kuramochi-Miyagawa S, Nakano T, Sasaki H, Pillai RS, Nakatsuji N, Chuma S.

PubMed	20022248	Journal	Curr Biol. 2009 Dec 29;19(24):2066-76.
Title	A broadly conserved pathway generates 3'UTR-directed primary piRNAs.
Authors	Robine N, Lau NC, Balla S, Jin Z, Okamura K, Kuramochi-Miyagawa S, Blower MD, Lai EC.

PubMed	25582079	Journal	Cell Res. 2015 Feb;25(2):193-207.
Title	MIWI and piRNA-mediated cleavage of messenger RNAs in mouse testes.
Authors	Zhang P, Kang JY, Gou LT, Wang J, Xue Y, Skogerboe G, Dai P, Huang DW, Chen R, Fu XD, Liu MF, He S.

PubMed	26588211	Journal	PLoS Genet. 2015 Nov 20;11(11):e1005652
Title	Conserved piRNA Expression from a Distinct Set of piRNA Cluster Loci in Eutherian Mammals
Authors	Chirn GW,Rahman R,Sytnikova YA,Matts JA,Zeng M,Gerlach D,Yu M,Berger B,Naramura M, Kile BT,Lau NC.

PubMed	26115953	Journal	Genes Dev. 2015 Jul 1; 29(13): 1403?415
Title	RNF17 blocks promiscuous activity of PIWI proteins in mouse testes
Authors	Wasik KA, Tam OH, Knott SR, Falciatori I, Hammell M, Vagin VV, Hannon GJ

PubMed	25262350	Journal	Nucleic Acids Res. 2014 Oct 29;42(19):11903-11
Title	HSP90a plays an important role in piRNA biogenesis and retrotransposon repression in mouse.
Authors	Ichiyanagi T,Ichiyanagi K,Ogawa A,Kuramochi-Miyagawa S,Nakano T,Chuma S,Sasaki H,Udono H.

PubMed	32674113	Journal	Nature. 2020 Aug;584(7822):635-639. doi: 10.1038/s41586-020-2557-5.
Title	SPOCD1 is an essential executor of piRNA-directed de novo DNA methylation.
Authors	Zoch A, Auchynnikava T, Berrens RV, Kabayama Y, Schöpp T, Heep M, Vasiliauskaitė L, Pérez-Rico YA, Cook AG, Shkumatava A, Rappsilber J, Allshire RC, O'Carroll D.

PubMed	33184219	Journal	Genes Dev. 2020 Dec 1;34(23-24):1637-1649. doi: 10.1101/gad.341602.120. Epub 2020 Nov 12.
Title	Sexually dimorphic DNA damage responses and mutation avoidance in the mouse germline.
Authors	Bloom JC, Schimenti JC.

PubMed	23523368	Journal	Mol Cell. 2013 Apr 11;50(1):67-81. doi: 10.1016/j.molcel.2013.02.016.
Title	An ancient transcription factor initiates the burst of piRNA production during early meiosis in mouse testes
Authors	Li XZ, Roy CK, Dong X, Bolcun-Filas E et al.