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Detail Information of piRNA: piR-mmu-6588

General Information
piRBase Id piR-mmu-6588 Accession DQ691073
Organism Mouse Number of methods 5
Sequence CACATCAGTCAAGGCATGCAGGGGAC Number of papers 15
Length 26 Golden piRNA -
Aliases piR-590; piR-106395; PIR1589; PIR189411; PIR199721;
Datasets
Dataset Accession Reads PubMed Method Tissue
4 N/A N/A 16751776 small RNA testis
5 N/A N/A 16751777 MILI IP testis
6 GSM113695 1 16778019 Chromatography testes tissue from Swiss Webster male mice, 8-10 weeks old
12 GSM822758 1 22121019 Miwi IP Testes, C57BL/6 P14 Miwi +/+
13 GSM822759 1 22121019 Miwi IP Testes, C57BL/6 P20 Miwi +/+
14 GSM822761 9 22121019 Miwi IP Testes, C57BL/6 Adult Miwi +/ADH
16 GSM822763 1 22121019 Miwi IP Testes, C57BL/6 Adult Miwi -/ADH
34 GSM684627 13 22842725 Miwi CLIP C57BL/6 adult testis
35 GSM684620 167 22842725 Mili CLIP C57BL/6 adult testis
36 GSM684621 195 22842725 Mili CLIP C57BL/6 adult testis
37 GSM684622 126 22842725 Mili CLIP C57BL/6 adult testis
38 GSM684623 284 22842725 Mili CLIP C57BL/6 adult testis
51 GSM610966 466 21602304 small RNA Male germ cell, Pachytene spermatocytes
52 GSM610967 929 21602304 small RNA Male germ cell, Round spermatids
65 GSM319961 2 18922463 small RNA 10 dpp MILI KO testis
66 GSM509275 8 20439430 small RNA MitoPLD+/+ E16.5 testis
68 GSM509277 5 20439430 small RNA Mili-/- E16.5 testis
121 GSM545783 390 20534472 Mov10L1 IP wild type adult testis
126 GSM466728 16 20059948 Mili IP Tdrd9+/- 14dpp testis
129 GSM466729 10 20059948 Mili IP Tdrd9+/- 14dpp testis
132 GSM475279 23 20022248 Miwi IP adult testis
133 GSM475280 232 20022248 Mili IP adult testis
217 GSM1653802 85 25582079 MIWI CLIP round spermatids
225 GSM1528807 439 26588211 small RNA Adult testes Asb1 ao31(Het)
226 GSM1528808 481 26588211 small RNA Adult testes Asb1 ao32(KO)
227 GSM1528809 597 26588211 small RNA Adult testes Asb1 ao34(Het)
228 GSM1528810 419 26588211 small RNA Adult testes Asb1 ao36(KO)
234 GSM433288 76 26115953 small RNA 18dpp hetero tdrd6 KO testes
235 GSM433289 115 26115953 small RNA 18dpp homo tdrd6 KO testes
236 GSM433290 128 26115953 small RNA 25dpp hetero tdrd6 KO testes
237 GSM433291 26 26115953 small RNA 25dpp homo tdrd6 KO testes
238 GSM433292 83 26115953 small RNA 6 weeks hetero tdrd6 KO testes
345 GSM475279 23 20022248 Miwi-IP testis 
346 GSM475280 232 20022248 Mili-IP testis 
347 GSM475281 473 20022248 small RNA testis 
441 GSM1096582 38 23523368 small RNA Wild Type 10.5 dpp testes
443 GSM1096583 25 23523368 small RNA Wild Type 12.5 dpp testes
444 GSM1096600 15 23523368 oxidized small RNA Wild Type 12.5 dpp testes
445 GSM1096584 69 23523368 small RNA Wild Type 14.5 dpp testes
446 GSM1096601 234 23523368 oxidized small RNA Wild Type 14.5 dpp testes
447 GSM1096585 23 23523368 small RNA Wild Type 17.5 dpp testes
448 GSM1096602 148 23523368 oxidized small RNA Wild Type 17.5 dpp testes
449 GSM1096586 144 23523368 small RNA Wild Type 20.5 dpp testes
450 GSM1096603 369 23523368 oxidized small RNA Wild Type 20.5 dpp testes
451 GSM1096587 116 23523368 small RNA Wild Type 6 weeks dpp testes
452 GSM1096604 186 23523368 oxidized small RNA Wild Type 6 weeks dpp testes
Location in GRCm38
1 best hit(s) with 0 mismatch(es) in GRCm38
No. Location Gene RepeatMaker
Location 1 17:66207704-66207730:+
piRNA Expression
Sample CPM
GSM179088 0
GSM261957 0
GSM261958 0
GSM261959 0
GSM319953 0
GSM319954 0
GSM319955 0
GSM319956 0
GSM319957 0
GSM319958 0
GSM319959 0
GSM319960 0
GSM319961 4.1036
GSM400967 225.5445
Sample CPM
GSM400968 192.6577
GSM400969 0.3344
GSM433288 17.7984
GSM433289 25.1552
GSM433290 27.1838
GSM433291 9.2489
GSM433292 20.1796
GSM433293 25.5229
GSM433294 0
GSM433295 0
GSM475279 2.2092
GSM475280 21.0935
GSM475281 44.3734
GSM678422 0.4245
The Expression of piRNA: piR-mmu-6588
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P value calculation
Sample1
Sample2
Target mRNA
No record.
Target lncRNA
No record.
Target Network
No record.
Disease Information
No record.
Reference
PubMed 16751776 Journal Nature. 2006 Jul 13;442(7099):199-202.
Title A germline-specific class of small RNAs binds mammalian Piwi proteins
Authors Girard A, Sachidanandam R, Hannon GJ, Carmell MA.
PubMed 16751777 Journal Nature. 2006 Jul 13;442(7099):203-7.
Title A novel class of small RNAs bind to MILI protein in mouse testes
Authors Aravin A, Gaidatzis D, Pfeffer S, Lagos-Quintana M, Landgraf P, Iovino N, Morris P, Brownstein MJ, Kuramochi-Miyagawa S, Nakano T, Chien M, Russo JJ, Ju J, Sheridan R, Sander C, Zavolan M, Tuschl T.
PubMed 16778019 Journal Science. 2006 Jul 21;313(5785):363-7.
Title Characterization of the piRNA complex from rat testes.
Authors Lau NC, Seto AG, Kim J, Kuramochi-Miyagawa S, Nakano T, Bartel DP, Kingston RE.
PubMed 22121019 Journal Nature. 2011 Nov 27;480(7376):264-7.
Title Miwi catalysis is required for piRNA amplification-independent LINE1 transposon silencing.
Authors Reuter M, Berninger P, Chuma S, Shah H, Hosokawa M, Funaya C, Antony C, Sachidanandam R, Pillai RS.
PubMed 22842725 Journal Nat Struct Mol Biol. 2012 Aug;19(8):773-81.
Title Mili and Miwi target RNA repertoire reveals piRNA biogenesis and function of Miwi in spermiogenesis.
Authors Vourekas A, Zheng Q, Alexiou P, Maragkakis M, Kirino Y, Gregory BD, Mourelatos Z.
PubMed 21602304 Journal RNA. 2011 Jul;17(7):1191-203.
Title piRNA profiling during specific stages of mouse spermatogenesis.
Authors Gan H, Lin X, Zhang Z, Zhang W, Liao S, Wang L, Han C.
PubMed 18922463 Journal Mol Cell. 2008 Sep 26;31(6):785-99.
Title A piRNA pathway primed by individual transposons is linked to de novo DNA methylation in mice.
Authors Aravin AA, Sachidanandam R, Bourc'his D, Schaefer C, Pezic D, Toth KF, Bestor T, Hannon GJ.
PubMed 20439430 Journal Genes Dev. 2010 May;24(9):887-92.
Title MVH in piRNA processing and gene silencing of retrotransposons.
Authors Kuramochi-Miyagawa S, Watanabe T, Gotoh K, Takamatsu K, Chuma S, Kojima-Kita K, Shiromoto Y, Asada N, Toyoda A, Fujiyama A, Totoki Y, Shibata T, Kimura T, Nakatsuji N, Noce T, Sasaki H, Nakano T.
PubMed 20534472 Journal Proc Natl Acad Sci U S A. 2010 Jun 29;107(26):11841-6.
Title Mouse MOV10L1 associates with Piwi proteins and is an essential component of the Piwi-interacting RNA (piRNA) pathway.
Authors Zheng K, Xiol J, Reuter M, Eckardt S, Leu NA, McLaughlin KJ, Stark A, Sachidanandam R, Pillai RS, Wang PJ.
PubMed 20059948 Journal Dev Cell. 2009 Dec;17(6):775-87.
Title The TDRD9-MIWI2 complex is essential for piRNA-mediated retrotransposon silencing in the mouse male germline.
Authors Shoji M, Tanaka T, Hosokawa M, Reuter M, Stark A, Kato Y, Kondoh G, Okawa K, Chujo T, Suzuki T, Hata K, Martin SL, Noce T, Kuramochi-Miyagawa S, Nakano T, Sasaki H, Pillai RS, Nakatsuji N, Chuma S.
PubMed 20022248 Journal Curr Biol. 2009 Dec 29;19(24):2066-76.
Title A broadly conserved pathway generates 3'UTR-directed primary piRNAs.
Authors Robine N, Lau NC, Balla S, Jin Z, Okamura K, Kuramochi-Miyagawa S, Blower MD, Lai EC.
PubMed 25582079 Journal Cell Res. 2015 Feb;25(2):193-207.
Title MIWI and piRNA-mediated cleavage of messenger RNAs in mouse testes.
Authors Zhang P, Kang JY, Gou LT, Wang J, Xue Y, Skogerboe G, Dai P, Huang DW, Chen R, Fu XD, Liu MF, He S.
PubMed 26588211 Journal PLoS Genet. 2015 Nov 20;11(11):e1005652
Title Conserved piRNA Expression from a Distinct Set of piRNA Cluster Loci in Eutherian Mammals
Authors Chirn GW,Rahman R,Sytnikova YA,Matts JA,Zeng M,Gerlach D,Yu M,Berger B,Naramura M, Kile BT,Lau NC.
PubMed 26115953 Journal Genes Dev. 2015 Jul 1; 29(13): 1403?415
Title RNF17 blocks promiscuous activity of PIWI proteins in mouse testes
Authors Wasik KA, Tam OH, Knott SR, Falciatori I, Hammell M, Vagin VV, Hannon GJ
PubMed 23523368 Journal Mol Cell. 2013 Apr 11;50(1):67-81. doi: 10.1016/j.molcel.2013.02.016.
Title An ancient transcription factor initiates the burst of piRNA production during early meiosis in mouse testes
Authors Li XZ, Roy CK, Dong X, Bolcun-Filas E et al.