NPInter v4.0

Documents functional interactions between noncoding RNAs and biomolecules

Examples: MALAT1, hsa-mir-107, NONHSAG008675, MI0000114, P04637
Molecule Information

Alias

-

Class

mRNA

Ensembl id

ENSMUSG00000089715

Organism

Mus musculus

Description

Component of a Polycomb group (PcG) multiprotein PRC1- like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. Possibly contributes to the target selectivity of the PRC1 complex by binding specific regions of chromatin (By similarity). Recruitment to chromatin might occur in an H3K27me3-independent fashion (PubMed:22226355, PubMed:16537902). May have a PRC1-independent function in embryonic stem cells (PubMed:22226355).

Interaction Information
Interaction ID Interact With Interaction Description Pubmed Organism