NPInter v4.0

Documents functional interactions between noncoding RNAs and biomolecules

Examples: MALAT1, hsa-mir-107, NONHSAG008675, MI0000114, P04637
Molecule Information

Alias

TDP-43

Class

protein

UniProt id

Q921F2

Organism

Mus musculus

Description

DNA and RNA-binding protein which regulates transcription and splicing. Involved in the regulation of CFTR splicing. It promotes CFTR exon 9 skipping by binding to the UG repeated motifs in the polymorphic region near the 3'-splice site of this exon. The resulting aberrant splicing is associated with pathological features typical of cystic fibrosis. May also be involved in microRNA biogenesis, apoptosis and cell division (By similarity).

Interaction Information
Interaction ID Interact With Interaction Description Pubmed Organism