Alias
TDP-43
Class
protein
UniProt id
Organism
Mus musculus
Description
DNA and RNA-binding protein which regulates transcription and splicing. Involved in the regulation of CFTR splicing. It promotes CFTR exon 9 skipping by binding to the UG repeated motifs in the polymorphic region near the 3'-splice site of this exon. The resulting aberrant splicing is associated with pathological features typical of cystic fibrosis. May also be involved in microRNA biogenesis, apoptosis and cell division (By similarity).
Interaction ID | Interact With | Interaction Description | Pubmed | Organism |
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