Interaction Profile
Interaction ID
ncRI-40989661
Interaction Molecules
U1 -- Sike1
Interaction Level
RNA-RNA
Interaction Class
binding
Data Source
RISE database
Tags
Organism
Mus musculus
Tissue or Cell Type
mES
Experiment
RAP
Description
RNA-RNA interaction from RISE database
Molecule Profile
Alias
-
Class
snRNA
Ensembl id
ENSMUSG00000099333
Description
snRNA
Alias
-
Class
mRNA
Ensembl id
ENSMUSG00000027854
Description
Physiological suppressor of IKK-epsilon and TBK1 that plays an inhibitory role in virus- and TLR3-triggered IRF3. Inhibits TLR3-mediated activation of interferon-stimulated response elements (ISRE) and the IFN-beta promoter. May act by disrupting the interactions of IKBKE or TBK1 with TICAM1/TRIF, IRF3 and DDX58/RIG-I. Does not inhibit NF-kappa-B activation pathways (By similarity).
Reference Information
| Pubmed ID | 25259926 | Journal | Cell |
|---|---|---|---|
| Title | RNA-RNA interactions enable specific targeting of noncoding RNAs to nascent Pre-mRNAs and chromatin sites. | ||
| Author | Engreitz JM, Sirokman K, McDonel P, Shishkin AA, Surka C, Russell P, Grossman SR, Chow AY, Guttman M, Lander ES | ||
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