Interaction: ncRI-40892432

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Interaction Profile

Interaction ID

ncRI-40892432

Interaction Molecules

mmu-miR-30e-3p -- Plxna1

Interaction Level

RNA-RNA

Interaction Class

binding

Data Source

TargetScan with Ago CLIP data

Tags

Organism

Mus musculus

Tissue or Cell Type

Keratinocytes cell

Experiment

AGO CLIP

Description

Conserved miRNAs target sites predicted by TargetScan overlap with the AGO CLIP dataset

Molecule Profile

mmu-miR-30e-3p

⇔

Plxna1

Alias

-

Class

miRNA

miRBase id

MI0000259

Description

Mus musculus miR-30e stem-loop

Alias

-

Class

mRNA

Ensembl id

ENSMUSG00000030084

Description

Coreceptor for SEMA3A, SEMA3C, SEMA3F and SEMA6D. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration. Class 3 semaphorins bind to a complex composed of a neuropilin and a plexin. The plexin modulates the affinity of the complex for specific semaphorins, and its cytoplasmic domain is required for the activation of down- stream signaling events in the cytoplasm.

Reference Information
Pubmed ID 26203562 Journal eLife
Title MicroRNA-203 represses selection and expansion of oncogenic Hras transformed tumor initiating cells.
Author Riemondy K, Wang XJ, Torchia EC, Roop DR, Yi R
Network View
Disease Annotation
Molecule Disease Data Source
mmu-miR-30e-3p acute disseminated encephalomyelitis MNDR Database
mmu-miR-30e-3p amyotrophic lateral sclerosis MNDR Database
mmu-miR-30e-3p atherosclerosis MNDR Database
mmu-miR-30e-3p Brain Injury, Chronic MNDR Database
mmu-miR-30e-3p cardiovascular system disease MNDR Database
mmu-miR-30e-3p encephalomyelitis MNDR Database
mmu-miR-30e-3p Encephalomyelitis, Autoimmune, Experimental MNDR Database
mmu-miR-30e-3p Encephalomyelitis, Venezuelan Equine MNDR Database
mmu-miR-30e-3p Epilepsia Partialis Continua MNDR Database
mmu-miR-30e-3p fragile X syndrome MNDR Database
mmu-miR-30e-3p Hyperalgesia MNDR Database
mmu-miR-30e-3p lung adenocarcinoma MNDR Database
mmu-miR-30e-3p medulloblastoma MNDR Database
mmu-miR-30e-3p Multiple Sclerosis, Chronic Progressive MNDR Database
mmu-miR-30e-3p muscular disease MNDR Database
mmu-miR-30e-3p Myotonic Dystrophy MNDR Database
mmu-miR-30e-3p Peripheral Nerve Injuries MNDR Database
mmu-miR-30e-3p Prostatic Neoplasms MNDR Database
mmu-miR-30e-3p relapsing-remitting multiple sclerosis MNDR Database
mmu-miR-30e-3p Rett syndrome MNDR Database
mmu-miR-30e-3p Seizures MNDR Database
mmu-miR-30e-3p West Nile fever MNDR Database