Interaction: ncRI-40661437

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Interaction Profile

Interaction ID

ncRI-40661437

Interaction Molecules

hsa-miR-629-3p -- PCBD1

Interaction Level

RNA-RNA

Interaction Class

binding

Data Source

miRanda with Ago CLIP data

Tags

Organism

Homo sapiens

Tissue or Cell Type

T-REx-293T;HEK293S

Experiment

AGO CLIP

Description

Conserved miRNAs target sites predicted by miRanda overlap with the AGO CLIP dataset

Molecule Profile

hsa-miR-629-3p

⇔

PCBD1

Alias

-

Class

miRNA

miRBase id

MI0003643

Description

Homo sapiens miR-629 stem-loop

Alias

-

Class

mRNA

Ensembl id

ENSG00000166228

Description

Involved in tetrahydrobiopterin biosynthesis. Seems to both prevent the formation of 7-pterins and accelerate the formation of quinonoid-BH2. Coactivator for HNF1A-dependent transcription. Regulates the dimerization of homeodomain protein HNF1A and enhances its transcriptional activity.

Reference Information
Pubmed ID 23824327 Journal Genes & development
Title Remodeling of Ago2-mRNA interactions upon cellular stress reflects miRNA complementarity and correlates with altered translation rates.
Author Karginov FV, Hannon GJ
Pubmed ID 29273203 Journal Journal of molecular biology
Title Transcriptome-wide Identification and Validation of Interactions between the miRNA Machinery and HuR on mRNA Targets.
Author Li Y, Estep JA, Karginov FV
Network View
Disease Annotation
Molecule Disease Data Source
hsa-miR-629-3p acromegaly MNDR Database
hsa-miR-629-3p acute myeloid leukemia MNDR Database
hsa-miR-629-3p Alzheimer's disease MNDR Database
hsa-miR-629-3p amyotrophic lateral sclerosis MNDR Database
hsa-miR-629-3p arthritis MNDR Database
hsa-miR-629-3p asthma MNDR Database
hsa-miR-629-3p autosomal recessive disease MNDR Database
hsa-miR-629-3p Barrett's adenocarcinoma MNDR Database
hsa-miR-629-3p B-cell lymphoma MNDR Database
hsa-miR-629-3p biliary tract cancer MNDR Database
hsa-miR-629-3p bladder urothelial carcinoma MNDR Database
hsa-miR-629-3p bone disease MNDR Database
hsa-miR-629-3p brain disease MNDR Database
hsa-miR-629-3p brain stem cancer MNDR Database
hsa-miR-629-3p breast cancer MNDR Database
hsa-miR-629-3p Breast Neoplasms MNDR Database
hsa-miR-629-3p cancer MNDR Database
hsa-miR-629-3p carcinoma MNDR Database
hsa-miR-629-3p Carcinoma, Ductal, Breast MNDR Database
hsa-miR-629-3p Carcinoma, Renal Cell MNDR Database
hsa-miR-629-3p cervical squamous cell carcinoma MNDR Database
hsa-miR-629-3p cholangiocarcinoma MNDR Database
hsa-miR-629-3p Chronic Pain MNDR Database
hsa-miR-629-3p colon adenocarcinoma MNDR Database
hsa-miR-629-3p colon cancer MNDR Database
hsa-miR-629-3p colorectal cancer MNDR Database
hsa-miR-629-3p diabetes mellitus MNDR Database
hsa-miR-629-3p Down syndrome MNDR Database
hsa-miR-629-3p esophageal carcinoma MNDR Database
hsa-miR-629-3p eye disease MNDR Database
hsa-miR-629-3p familiar ovarian carcinoma MNDR Database
hsa-miR-629-3p Glioblastoma MNDR Database
hsa-miR-629-3p Growth Hormone-Secreting Pituitary Adenoma MNDR Database
hsa-miR-629-3p head and neck squamous cell carcinoma MNDR Database
hsa-miR-629-3p heart disease MNDR Database
hsa-miR-629-3p hepatocellular carcinoma MNDR Database
hsa-miR-629-3p Her2-receptor positive breast cancer MNDR Database
hsa-miR-629-3p Hodgkin's lymphoma MNDR Database
hsa-miR-629-3p hypersensitivity reaction type II disease MNDR Database
hsa-miR-629-3p hypertension MNDR Database
hsa-miR-629-3p inflammatory bowel disease MNDR Database
hsa-miR-629-3p intellectual disability MNDR Database
hsa-miR-629-3p kidney disease MNDR Database
hsa-miR-629-3p large cell neuroendocrine cancer MNDR Database
hsa-miR-629-3p leukemia MNDR Database
hsa-miR-629-3p Liver Neoplasms MNDR Database
hsa-miR-629-3p lung adenocarcinoma MNDR Database
hsa-miR-629-3p lung cancer MNDR Database
hsa-miR-629-3p lung disease MNDR Database
hsa-miR-629-3p lung small cell carcinoma MNDR Database
hsa-miR-629-3p lung squamous cell carcinoma MNDR Database
hsa-miR-629-3p Lupus Vulgaris MNDR Database
hsa-miR-629-3p lymphoma MNDR Database
hsa-miR-629-3p malignant glioma MNDR Database
hsa-miR-629-3p malignant pleural mesothelioma MNDR Database
hsa-miR-629-3p melanoma MNDR Database
hsa-miR-629-3p Multiple Sclerosis, Chronic Progressive MNDR Database
hsa-miR-629-3p Myasthenia Gravis, Autoimmune, Experimental MNDR Database
hsa-miR-629-3p nasopharynx carcinoma MNDR Database
hsa-miR-629-3p nephroblastoma MNDR Database
hsa-miR-629-3p neurodegenerative disease MNDR Database
hsa-miR-629-3p osteosarcoma MNDR Database
hsa-miR-629-3p ovarian carcinoma MNDR Database
hsa-miR-629-3p Ovarian Neoplasms MNDR Database
hsa-miR-629-3p pancreatic adenocarcinoma MNDR Database
hsa-miR-629-3p pancreatic cancer MNDR Database
hsa-miR-629-3p pancreatic ductal adenocarcinoma MNDR Database
hsa-miR-629-3p papillary renal cell carcinoma MNDR Database
hsa-miR-629-3p pituitary adenoma MNDR Database
hsa-miR-629-3p Precursor Cell Lymphoblastic Leukemia-Lymphoma MNDR Database
hsa-miR-629-3p progesterone-receptor negative breast cancer MNDR Database
hsa-miR-629-3p progesterone-receptor positive breast cancer MNDR Database
hsa-miR-629-3p progressive multifocal leukoencephalopathy MNDR Database
hsa-miR-629-3p prostate adenocarcinoma MNDR Database
hsa-miR-629-3p Prostatic Neoplasms MNDR Database
hsa-miR-629-3p rectum adenocarcinoma MNDR Database
hsa-miR-629-3p relapsing-remitting multiple sclerosis MNDR Database
hsa-miR-629-3p renal cell carcinoma MNDR Database
hsa-miR-629-3p renal clear cell carcinoma MNDR Database
hsa-miR-629-3p retinal degeneration MNDR Database
hsa-miR-629-3p skin disease MNDR Database
hsa-miR-629-3p skin melanoma MNDR Database
hsa-miR-629-3p small intestine cancer MNDR Database
hsa-miR-629-3p stomach cancer MNDR Database
hsa-miR-629-3p Stroke, Lacunar MNDR Database
hsa-miR-629-3p Subarachnoid Hemorrhage, Traumatic MNDR Database
hsa-miR-629-3p testicular cancer MNDR Database
hsa-miR-629-3p testicular germ cell cancer MNDR Database
hsa-miR-629-3p thyroid cancer MNDR Database
hsa-miR-629-3p thyroid carcinoma MNDR Database
hsa-miR-629-3p triple-receptor negative breast cancer MNDR Database
hsa-miR-629-3p ulcerative colitis MNDR Database
hsa-miR-629-3p uterine corpus endometrial carcinoma MNDR Database
hsa-miR-629-3p vascular disease MNDR Database
hsa-miR-629-3p hyperphenylalaninemia, bh4-deficient, d eDGAR Database