Interaction ID
ncRI-40659277
Interaction Molecules
hsa-miR-1297 -- FLRT2
Interaction Level
RNA-RNA
Interaction Class
binding
Data Source
miRanda with Ago CLIP data
Tags
Organism
Homo sapiens
Tissue or Cell Type
T-REx-293T
Experiment
AGO CLIP
Description
Conserved miRNAs target sites predicted by miRanda overlap with the AGO CLIP dataset
Alias
-
Class
mRNA
Ensembl id
ENSG00000185070
Description
Functions in cell-cell adhesion, cell migration and axon guidance. Mediates cell-cell adhesion via its interactions with ADGRL3 and probably also other latrophilins that are expressed at the surface of adjacent cells. May play a role in the migration of cortical neurons during brain development via its interaction with UNC5D. Mediates axon growth cone collapse and plays a repulsive role in neuron guidance via its interaction with UNC5D, and possibly also other UNC-5 family members. Plays a role in fibroblast growth factor-mediated signaling cascades. Required for normal organization of the cardiac basement membrane during embryogenesis, and for normal embryonic epicardium and heart morphogenesis.
| Pubmed ID | 29273203 | Journal | Journal of molecular biology |
|---|---|---|---|
| Title | Transcriptome-wide Identification and Validation of Interactions between the miRNA Machinery and HuR on mRNA Targets. | ||
| Author | Li Y, Estep JA, Karginov FV | ||
| Molecule | Disease | Data Source |
|---|---|---|
| hsa-miR-1297 | Brain Injury, Chronic | MNDR Database |
| hsa-miR-1297 | breast cancer | MNDR Database |
| hsa-miR-1297 | Breast Neoplasms | MNDR Database |
| hsa-miR-1297 | cancer | MNDR Database |
| hsa-miR-1297 | colorectal cancer | MNDR Database |
| hsa-miR-1297 | Down syndrome | MNDR Database |
| hsa-miR-1297 | familiar ovarian carcinoma | MNDR Database |
| hsa-miR-1297 | Glioblastoma | MNDR Database |
| hsa-miR-1297 | hepatocellular carcinoma | MNDR Database |
| hsa-miR-1297 | Her2-receptor positive breast cancer | MNDR Database |
| hsa-miR-1297 | Hyperalgesia | MNDR Database |
| hsa-miR-1297 | liposarcoma | MNDR Database |
| hsa-miR-1297 | lung adenocarcinoma | MNDR Database |
| hsa-miR-1297 | lung cancer | MNDR Database |
| hsa-miR-1297 | Machado-Joseph disease | MNDR Database |
| hsa-miR-1297 | malignant glioma | MNDR Database |
| hsa-miR-1297 | nasopharynx carcinoma | MNDR Database |
| hsa-miR-1297 | neurodegenerative disease | MNDR Database |
| hsa-miR-1297 | pancreatic ductal adenocarcinoma | MNDR Database |
| hsa-miR-1297 | progesterone-receptor negative breast cancer | MNDR Database |
| hsa-miR-1297 | progesterone-receptor positive breast cancer | MNDR Database |
| hsa-miR-1297 | stomach cancer | MNDR Database |
| hsa-miR-1297 | temporal lobe epilepsy | MNDR Database |
| hsa-miR-1297 | vascular disease | MNDR Database |