Interaction Profile
Interaction ID
ncRI-40646583
Interaction Molecules
hsa-let-7f-1-3p -- LRIG3
Interaction Level
RNA-RNA
Interaction Class
binding
Data Source
TargetScan with Ago CLIP data
Tags
Organism
Homo sapiens
Tissue or Cell Type
T-REx-293T;HEK293S
Experiment
AGO CLIP
Description
Conserved miRNAs target sites predicted by TargetScan and miRanda overlap with the AGO CLIP dataset
Molecule Profile
Alias
-
Class
mRNA
Ensembl id
ENSG00000139263
Description
May play a role in craniofacial and inner ear morphogenesis during embryonic development. May act within the otic vesicle epithelium to control formation of the lateral semicircular canal in the inner ear, possibly by restricting the expression of NTN1 (By similarity).
Reference Information
| Pubmed ID | 23824327 | Journal | Genes & development |
|---|---|---|---|
| Title | Remodeling of Ago2-mRNA interactions upon cellular stress reflects miRNA complementarity and correlates with altered translation rates. | ||
| Author | Karginov FV, Hannon GJ | ||
| Pubmed ID | 29273203 | Journal | Journal of molecular biology |
|---|---|---|---|
| Title | Transcriptome-wide Identification and Validation of Interactions between the miRNA Machinery and HuR on mRNA Targets. | ||
| Author | Li Y, Estep JA, Karginov FV | ||
Network View
Disease Annotation
| Molecule | Disease | Data Source |
|---|---|---|
| hsa-let-7f-1-3p | acute myeloid leukemia | MNDR Database |
| hsa-let-7f-1-3p | acute T cell leukemia | MNDR Database |
| hsa-let-7f-1-3p | adenocarcinoma | MNDR Database |
| hsa-let-7f-1-3p | adrenocortical carcinoma | MNDR Database |
| hsa-let-7f-1-3p | Adrenocortical Carcinoma | MNDR Database |
| hsa-let-7f-1-3p | Alzheimer's disease | MNDR Database |
| hsa-let-7f-1-3p | amyotrophic lateral sclerosis | MNDR Database |
| hsa-let-7f-1-3p | asthma | MNDR Database |
| hsa-let-7f-1-3p | autosomal recessive disease | MNDR Database |
| hsa-let-7f-1-3p | Barrett's adenocarcinoma | MNDR Database |
| hsa-let-7f-1-3p | B-cell lymphoma | MNDR Database |
| hsa-let-7f-1-3p | biliary tract cancer | MNDR Database |
| hsa-let-7f-1-3p | brain disease | MNDR Database |
| hsa-let-7f-1-3p | breast cancer | MNDR Database |
| hsa-let-7f-1-3p | Breast Neoplasms | MNDR Database |
| hsa-let-7f-1-3p | bronchiolo-alveolar adenocarcinoma | MNDR Database |
| hsa-let-7f-1-3p | Burkitt lymphoma | MNDR Database |
| hsa-let-7f-1-3p | cancer | MNDR Database |
| hsa-let-7f-1-3p | carcinoma | MNDR Database |
| hsa-let-7f-1-3p | Carcinoma, Ductal, Breast | MNDR Database |
| hsa-let-7f-1-3p | Carcinoma, Non-Small-Cell Lung | MNDR Database |
| hsa-let-7f-1-3p | Carcinoma, Renal Cell | MNDR Database |
| hsa-let-7f-1-3p | cholangiocarcinoma | MNDR Database |
| hsa-let-7f-1-3p | chronic kidney disease | MNDR Database |
| hsa-let-7f-1-3p | chronic lymphocytic leukemia | MNDR Database |
| hsa-let-7f-1-3p | Cocaine-Related Disorders | MNDR Database |
| hsa-let-7f-1-3p | colon adenocarcinoma | MNDR Database |
| hsa-let-7f-1-3p | colon cancer | MNDR Database |
| hsa-let-7f-1-3p | colorectal cancer | MNDR Database |
| hsa-let-7f-1-3p | Crohn's disease | MNDR Database |
| hsa-let-7f-1-3p | cystic nephroma | MNDR Database |
| hsa-let-7f-1-3p | dermatomyositis | MNDR Database |
| hsa-let-7f-1-3p | diabetes mellitus | MNDR Database |
| hsa-let-7f-1-3p | DiGeorge syndrome | MNDR Database |
| hsa-let-7f-1-3p | Digestive System Neoplasms | MNDR Database |
| hsa-let-7f-1-3p | dilated cardiomyopathy | MNDR Database |
| hsa-let-7f-1-3p | embryonal cancer | MNDR Database |
| hsa-let-7f-1-3p | encephalomyelitis | MNDR Database |
| hsa-let-7f-1-3p | endometrial cancer | MNDR Database |
| hsa-let-7f-1-3p | endometriosis | MNDR Database |
| hsa-let-7f-1-3p | Ependymoma | MNDR Database |
| hsa-let-7f-1-3p | esophageal cancer | MNDR Database |
| hsa-let-7f-1-3p | Ewing sarcoma | MNDR Database |
| hsa-let-7f-1-3p | eye disease | MNDR Database |
| hsa-let-7f-1-3p | familiar ovarian carcinoma | MNDR Database |
| hsa-let-7f-1-3p | fragile X syndrome | MNDR Database |
| hsa-let-7f-1-3p | gallbladder adenocarcinoma | MNDR Database |
| hsa-let-7f-1-3p | gastric adenocarcinoma | MNDR Database |
| hsa-let-7f-1-3p | gastric lymphoma | MNDR Database |
| hsa-let-7f-1-3p | gastrointestinal system cancer | MNDR Database |
| hsa-let-7f-1-3p | Glioblastoma | MNDR Database |
| hsa-let-7f-1-3p | gout | MNDR Database |
| hsa-let-7f-1-3p | head and neck cancer | MNDR Database |
| hsa-let-7f-1-3p | head and neck squamous cell carcinoma | MNDR Database |
| hsa-let-7f-1-3p | heart disease | MNDR Database |
| hsa-let-7f-1-3p | Heart Failure | MNDR Database |
| hsa-let-7f-1-3p | hepatitis B | MNDR Database |
| hsa-let-7f-1-3p | hepatitis C | MNDR Database |
| hsa-let-7f-1-3p | hepatocellular carcinoma | MNDR Database |
| hsa-let-7f-1-3p | Her2-receptor positive breast cancer | MNDR Database |
| hsa-let-7f-1-3p | Hodgkin's lymphoma | MNDR Database |
| hsa-let-7f-1-3p | hypertension | MNDR Database |
| hsa-let-7f-1-3p | Hypertrophy | MNDR Database |
| hsa-let-7f-1-3p | inclusion body myositis | MNDR Database |
| hsa-let-7f-1-3p | Inflammation | MNDR Database |
| hsa-let-7f-1-3p | Influenza, Human | MNDR Database |
| hsa-let-7f-1-3p | intellectual disability | MNDR Database |
| hsa-let-7f-1-3p | interstitial lung disease | MNDR Database |
| hsa-let-7f-1-3p | intracranial aneurysm | MNDR Database |
| hsa-let-7f-1-3p | Intracranial Hemorrhage, Hypertensive | MNDR Database |
| hsa-let-7f-1-3p | Kaposi's sarcoma | MNDR Database |
| hsa-let-7f-1-3p | keratitis | MNDR Database |
| hsa-let-7f-1-3p | kidney cancer | MNDR Database |
| hsa-let-7f-1-3p | Lafora disease | MNDR Database |
| hsa-let-7f-1-3p | leiomyoma | MNDR Database |
| hsa-let-7f-1-3p | Lesch-Nyhan syndrome | MNDR Database |
| hsa-let-7f-1-3p | leukemia | MNDR Database |
| hsa-let-7f-1-3p | liposarcoma | MNDR Database |
| hsa-let-7f-1-3p | liver cancer | MNDR Database |
| hsa-let-7f-1-3p | Liver Neoplasms | MNDR Database |
| hsa-let-7f-1-3p | lung adenocarcinoma | MNDR Database |
| hsa-let-7f-1-3p | lung cancer | MNDR Database |
| hsa-let-7f-1-3p | lung disease | MNDR Database |
| hsa-let-7f-1-3p | lung squamous cell carcinoma | MNDR Database |
| hsa-let-7f-1-3p | Lymphoblastoid | MNDR Database |
| hsa-let-7f-1-3p | lymphoma | MNDR Database |
| hsa-let-7f-1-3p | Lymphoma, Non-Hodgkin | MNDR Database |
| hsa-let-7f-1-3p | Lymphoma, Primary Effusion | MNDR Database |
| hsa-let-7f-1-3p | Machado-Joseph disease | MNDR Database |
| hsa-let-7f-1-3p | macular degeneration | MNDR Database |
| hsa-let-7f-1-3p | malignant glioma | MNDR Database |
| hsa-let-7f-1-3p | malignant pleural mesothelioma | MNDR Database |
| hsa-let-7f-1-3p | medulloblastoma | MNDR Database |
| hsa-let-7f-1-3p | medulloepithelioma | MNDR Database |
| hsa-let-7f-1-3p | melanoma | MNDR Database |
| hsa-let-7f-1-3p | Mesothelioma | MNDR Database |
| hsa-let-7f-1-3p | metabolic syndrome X | MNDR Database |
| hsa-let-7f-1-3p | multiple myeloma | MNDR Database |
| hsa-let-7f-1-3p | Multiple Sclerosis, Chronic Progressive | MNDR Database |
| hsa-let-7f-1-3p | Muscular Disorders, Atrophic | MNDR Database |
| hsa-let-7f-1-3p | myasthenia gravis | MNDR Database |
| hsa-let-7f-1-3p | Myasthenia Gravis, Autoimmune, Experimental | MNDR Database |
| hsa-let-7f-1-3p | mycosis fungoides | MNDR Database |
| hsa-let-7f-1-3p | myelodysplastic/myeloproliferative neoplasm | MNDR Database |
| hsa-let-7f-1-3p | nasopharynx carcinoma | MNDR Database |
| hsa-let-7f-1-3p | nemaline myopathy | MNDR Database |
| hsa-let-7f-1-3p | Neoplasms | MNDR Database |
| hsa-let-7f-1-3p | nephroblastoma | MNDR Database |
| hsa-let-7f-1-3p | neuroblastoma | MNDR Database |
| hsa-let-7f-1-3p | neurodegenerative disease | MNDR Database |
| hsa-let-7f-1-3p | neuromyelitis optica | MNDR Database |
| hsa-let-7f-1-3p | Niemann-Pick disease | MNDR Database |
| hsa-let-7f-1-3p | oligodendroglioma | MNDR Database |
| hsa-let-7f-1-3p | oral squamous cell carcinoma | MNDR Database |
| hsa-let-7f-1-3p | osteosarcoma | MNDR Database |
| hsa-let-7f-1-3p | ovarian clear cell carcinoma | MNDR Database |
| hsa-let-7f-1-3p | Ovarian Neoplasms | MNDR Database |
| hsa-let-7f-1-3p | pancreatic cancer | MNDR Database |
| hsa-let-7f-1-3p | pancreatic ductal adenocarcinoma | MNDR Database |
| hsa-let-7f-1-3p | papillary renal cell carcinoma | MNDR Database |
| hsa-let-7f-1-3p | Parkinson's disease | MNDR Database |
| hsa-let-7f-1-3p | periodontitis | MNDR Database |
| hsa-let-7f-1-3p | pituitary adenoma | MNDR Database |
| hsa-let-7f-1-3p | pleuropulmonary blastoma | MNDR Database |
| hsa-let-7f-1-3p | Precursor Cell Lymphoblastic Leukemia-Lymphoma | MNDR Database |
| hsa-let-7f-1-3p | pre-eclampsia | MNDR Database |
| hsa-let-7f-1-3p | progesterone-receptor negative breast cancer | MNDR Database |
| hsa-let-7f-1-3p | progesterone-receptor positive breast cancer | MNDR Database |
| hsa-let-7f-1-3p | prostate adenocarcinoma | MNDR Database |
| hsa-let-7f-1-3p | Prostatic Neoplasms | MNDR Database |
| hsa-let-7f-1-3p | Pseudorabies | MNDR Database |
| hsa-let-7f-1-3p | rectum adenocarcinoma | MNDR Database |
| hsa-let-7f-1-3p | relapsing-remitting multiple sclerosis | MNDR Database |
| hsa-let-7f-1-3p | renal cell carcinoma | MNDR Database |
| hsa-let-7f-1-3p | renal clear cell carcinoma | MNDR Database |
| hsa-let-7f-1-3p | retinoblastoma | MNDR Database |
| hsa-let-7f-1-3p | Sarcopenia | MNDR Database |
| hsa-let-7f-1-3p | schizophrenia | MNDR Database |
| hsa-let-7f-1-3p | serous cystadenocarcinoma | MNDR Database |
| hsa-let-7f-1-3p | Sertoli-Leydig cell tumor | MNDR Database |
| hsa-let-7f-1-3p | skin disease | MNDR Database |
| hsa-let-7f-1-3p | squamous cell carcinoma | MNDR Database |
| hsa-let-7f-1-3p | stomach cancer | MNDR Database |
| hsa-let-7f-1-3p | Stroke | MNDR Database |
| hsa-let-7f-1-3p | Stroke, Lacunar | MNDR Database |
| hsa-let-7f-1-3p | synovial sarcoma | MNDR Database |
| hsa-let-7f-1-3p | systemic lupus erythematosus | MNDR Database |
| hsa-let-7f-1-3p | T-cell leukemia | MNDR Database |
| hsa-let-7f-1-3p | temporal lobe epilepsy | MNDR Database |
| hsa-let-7f-1-3p | thrombotic thrombocytopenic purpura | MNDR Database |
| hsa-let-7f-1-3p | thyroid cancer | MNDR Database |
| hsa-let-7f-1-3p | ulcerative colitis | MNDR Database |
| hsa-let-7f-1-3p | Urinary Bladder Neoplasms | MNDR Database |
| hsa-let-7f-1-3p | uterine cancer | MNDR Database |
| hsa-let-7f-1-3p | Uterine Cervical Neoplasms | MNDR Database |
| hsa-let-7f-1-3p | vascular disease | MNDR Database |
| hsa-let-7f-1-3p | X-linked disease | MNDR Database |