Interaction Profile
Interaction ID
ncRI-40645142
Interaction Molecules
hsa-miR-135a-5p -- NUDT19
Interaction Level
RNA-RNA
Interaction Class
binding
Data Source
miRanda with Ago CLIP data
Tags
Organism
Homo sapiens
Tissue or Cell Type
T-REx-293T;HEK293S
Experiment
AGO CLIP
Description
Conserved miRNAs target sites predicted by miRanda overlap with the AGO CLIP dataset
Molecule Profile
Alias
-
Class
mRNA
Ensembl id
ENSG00000213965
Description
Coenzyme A diphosphatase that mediates the hydrolysis of a wide range of CoA esters, including choloyl-CoA and branched- chain fatty-acyl-CoA esters. At low substrate concentrations medium and long-chain fatty-acyl-CoA esters are the primary substrates (By similarity).
Reference Information
| Pubmed ID | 23824327 | Journal | Genes & development |
|---|---|---|---|
| Title | Remodeling of Ago2-mRNA interactions upon cellular stress reflects miRNA complementarity and correlates with altered translation rates. | ||
| Author | Karginov FV, Hannon GJ | ||
| Pubmed ID | 29273203 | Journal | Journal of molecular biology |
|---|---|---|---|
| Title | Transcriptome-wide Identification and Validation of Interactions between the miRNA Machinery and HuR on mRNA Targets. | ||
| Author | Li Y, Estep JA, Karginov FV | ||
Network View
Disease Annotation
| Molecule | Disease | Data Source |
|---|---|---|
| hsa-miR-135a-5p | adenocarcinoma | MNDR Database |
| hsa-miR-135a-5p | adrenocortical carcinoma | MNDR Database |
| hsa-miR-135a-5p | breast cancer | MNDR Database |
| hsa-miR-135a-5p | Carcinoma, Non-Small-Cell Lung | MNDR Database |
| hsa-miR-135a-5p | colorectal cancer | MNDR Database |
| hsa-miR-135a-5p | endometriosis | MNDR Database |
| hsa-miR-135a-5p | Ependymoma | MNDR Database |
| hsa-miR-135a-5p | Heart Failure | MNDR Database |
| hsa-miR-135a-5p | hepatocellular carcinoma | MNDR Database |
| hsa-miR-135a-5p | lung cancer | MNDR Database |
| hsa-miR-135a-5p | lymphoma | MNDR Database |
| hsa-miR-135a-5p | malignant glioma | MNDR Database |
| hsa-miR-135a-5p | medulloblastoma | MNDR Database |
| hsa-miR-135a-5p | Neoplasms | MNDR Database |
| hsa-miR-135a-5p | pancreatic cancer | MNDR Database |
| hsa-miR-135a-5p | Prostatic Neoplasms | MNDR Database |
| hsa-miR-135a-5p | renal cell carcinoma | MNDR Database |
| hsa-miR-135a-5p | stomach cancer | MNDR Database |