Interaction Profile
Interaction ID
ncRI-40644821
Interaction Molecules
hsa-miR-921 -- ANLN
Interaction Level
RNA-RNA
Interaction Class
binding
Data Source
miRanda with Ago CLIP data
Tags
Organism
Homo sapiens
Tissue or Cell Type
T-REx-293T
Experiment
AGO CLIP
Description
Conserved miRNAs target sites predicted by miRanda overlap with the AGO CLIP dataset
Molecule Profile
Alias
-
Class
mRNA
Ensembl id
ENSG00000011426
Description
Required for cytokinesis (PubMed:16040610). Essential for the structural integrity of the cleavage furrow and for completion of cleavage furrow ingression. Plays a role in bleb assembly during metaphase and anaphase of mitosis (PubMed:23870127). May play a significant role in podocyte cell migration (PubMed:24676636).
Reference Information
| Pubmed ID | 29273203 | Journal | Journal of molecular biology |
|---|---|---|---|
| Title | Transcriptome-wide Identification and Validation of Interactions between the miRNA Machinery and HuR on mRNA Targets. | ||
| Author | Li Y, Estep JA, Karginov FV | ||
Network View
Disease Annotation
| Molecule | Disease | Data Source |
|---|---|---|
| hsa-miR-921 | brain disease | MNDR Database |
| hsa-miR-921 | breast cancer | MNDR Database |
| hsa-miR-921 | Breast Neoplasms | MNDR Database |
| hsa-miR-921 | cancer | MNDR Database |
| hsa-miR-921 | carcinoma | MNDR Database |
| hsa-miR-921 | colon cancer | MNDR Database |
| hsa-miR-921 | familiar ovarian carcinoma | MNDR Database |
| hsa-miR-921 | heart disease | MNDR Database |
| hsa-miR-921 | Her2-receptor positive breast cancer | MNDR Database |
| hsa-miR-921 | Hodgkin's lymphoma | MNDR Database |
| hsa-miR-921 | intracranial aneurysm | MNDR Database |
| hsa-miR-921 | leukemia | MNDR Database |
| hsa-miR-921 | lung adenocarcinoma | MNDR Database |
| hsa-miR-921 | lung cancer | MNDR Database |
| hsa-miR-921 | lung disease | MNDR Database |
| hsa-miR-921 | lymphoma | MNDR Database |
| hsa-miR-921 | nasopharynx carcinoma | MNDR Database |
| hsa-miR-921 | nephroblastoma | MNDR Database |
| hsa-miR-921 | neurodegenerative disease | MNDR Database |
| hsa-miR-921 | oral squamous cell carcinoma | MNDR Database |
| hsa-miR-921 | pancreatic adenocarcinoma | MNDR Database |
| hsa-miR-921 | pancreatic cancer | MNDR Database |
| hsa-miR-921 | progesterone-receptor positive breast cancer | MNDR Database |
| hsa-miR-921 | relapsing-remitting multiple sclerosis | MNDR Database |
| hsa-miR-921 | stomach cancer | MNDR Database |
| hsa-miR-921 | vascular disease | MNDR Database |
| hsa-miR-921 | focal segmental glomerulosclerosis | eDGAR Database |