Interaction Profile
Interaction ID
ncRI-40044028
Interaction Molecules
RP11-282D2.2 -- TNRC6A
Interaction Level
RNA-Protein
Interaction Class
binding
Data Source
High-throughput data
Tags
Organism
Homo sapiens
Tissue or Cell Type
-
Experiment
PAR-CLIP
Description
collections from lncRNome
Molecule Profile
Alias
TNRC6A-C
Class
protein
UniProt id
Description
Plays a role in RNA-mediated gene silencing by both micro-RNAs (miRNAs) and short interfering RNAs (siRNAs). Required for miRNA-dependent repression of translation and for siRNA-dependent endonucleolytic cleavage of complementary mRNAs by argonaute family proteins. As scaffoldng protein associates with argonaute proteins bound to partially complementary mRNAs and simultaneously can recruit CCR4-NOT and PAN deadenylase complexes.
Reference Information
| Pubmed ID | 23846593 | Journal | Database : the journal of biological databases and curation |
|---|---|---|---|
| Title | lncRNome: a comprehensive knowledgebase of human long noncoding RNAs. | ||
| Author | Bhartiya D, Pal K, Ghosh S, Kapoor S, Jalali S, Panwar B, Jain S, Sati S, Sengupta S, Sachidanandan C, Raghava GP, Sivasubbu S, Scaria V | ||
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