Interaction ID
ncRI-40015874
Interaction Molecules
CEP104 -- hnRNPL
Interaction Level
RNA-Protein
Interaction Class
binding
Data Source
High-throughput data
Tags
Organism
Homo sapiens
Tissue or Cell Type
CD4+ T;Jurkat;JSL1
Experiment
CLIP-Seq
Description
Binding profile from resting CD4 combined CLIP-seq experiments, this sample represents 3 CD4 resting samples
Alias
HNRPL;hnRNP L
Class
protein
UniProt id
Description
Splicing factor binding to exonic or intronic sites and acting as either an activator or repressor of exon inclusion. Exhibits a binding preference for CA-rich elements. Component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complexes and associated with most nascent transcripts. Associates, together with APEX1, to the negative calcium responsive element (nCaRE) B2 of the APEX2 promoter.
| Pubmed ID | 24164894 | Journal | Molecular and cellular biology |
|---|---|---|---|
| Title | Transcriptome-wide RNA interaction profiling reveals physical and functional targets of hnRNP L in human T cells. | ||
| Author | Shankarling G, Cole BS, Mallory MJ, Lynch KW | ||
| Binding Site ID | Location | Conservation Score |
|---|---|---|
| 330168 | chr1:3748214-3748269 | 0.00216363636364 |
| 330169 | chr1:3748220-3748250 | 0.0038 |
| 330170 | chr1:3748220-3748250 | 0.0038 |
| 330171 | chr1:3748220-3748251 | 0.00367741935484 |
| 330184 | chr1:3748766-3748951 | 0.717994594595 |
| 330185 | chr1:3748776-3749125 | 0.510358166189 |
| 330186 | chr1:3748776-3749125 | 0.510358166189 |
| 330188 | chr1:3748842-3748923 | 0.808864197531 |
| 330191 | chr1:3749046-3749123 | 0.197688311688 |
| 330192 | chr1:3749046-3749123 | 0.197688311688 |
| 330210 | chr1:3750281-3750307 | 7.69230769231e |
| 330216 | chr1:3750532-3750567 | 0.680342857143 |
| 330217 | chr1:3750533-3750568 | 0.698085714286 |
| Molecule | Disease | Data Source |
|---|---|---|
| CEP104 | joubert syndrome | eDGAR Database |