Specific Information of Small Protein : SPROHSA216137
General Information
| Small Protein ID | SPROHSA216137 |
| Organism | Human (Homo sapiens) |
| Small Protein Sequence | MSRPNSPRGLGVVLSAHARKPGPDAAVRRTSRRVRLNAASCQAARDALSLRRLLAS* |
| RNA Sequence | ATGTCGCGGCCGAACTCACCTCGTGGCCTCGGCGTGGTGCTCTCAGCTCATGCCCGGAAACCAGGTCCCGACGCCGCGGTCAGACGGACCTCTAGACGCGTCCGCCTCAATGCCGCCAGCTGCCAGGCCGCCCGTGACGCGTTAAGCCTGCGCCGCCTCCTGGCTTCGTGA |
| Protein Length | 56 |
| Start Codon | ATG |
| Location | chr9:122264695-122264866:+ |
| Blocks | 122264695-122264866 |
| Mean PhyloCSF | -5.71631574056 |
| Data Source | Ribosome profiling; Literature; |
| Related Genes | ENSG00000148187; MRRF; ENSG00000119446; RBM18; |
| Mass (Da) | mono. 5988.3; avg. 5991.9 |
Ribosome profiling
| Ribo-seq ID | Ensembl Gene ID | Ensembl Transcript ID | Symbol | Gene Type | TIS Type | Ribo P value | TIS P value | Start On Trans | Stop On Trans | In-frame Count | Ribo-seq RPKM |
|---|
| GSE105082 | ENSG00000148187.18 | ENST00000297908.7 | MRRF | Protein_coding | 5'UTR | 0.035009 | None | 93 | 264 | 5 | 1.98698325 |
| GSE105082_alt | ENSG00000148187.18 | ENST00000297908.7 | MRRF | Protein_coding | 5'UTR | 0.035009 | None | 93 | 264 | 5 | 1.98698325 |
| GSE83493 | ENSG00000148187.18 | ENST00000297908.7 | MRRF | Protein_coding | 5'UTR | 0.023908 | None | 93 | 264 | 13 | 9.11070144 |
| SRR964946_alt | ENSG00000148187.18 | ENST00000297908.7 | MRRF | Protein_coding | 5'UTR | 0.027168 | 0.006517 | 93 | 264 | NA | NA |
| Min Ribo P value | 0.023908 |
| Min TIS P value | None |
| Ribo-seq ID | Cell or Tissue | Phenotype | Ribo-seq Source Details | PMID |
|---|
| GSE105082 | HELA | Cervical cancer | GSM2817679; GSM2817680 | 30591072; |
| GSE105082_alt | HELA | Cervical cancer | GSM2817679; GSM2817680 | 30591072; |
| GSE83493 | HeLa S3 | Cervical cancer | GSM2204389; GSM2204390; GSM2204391; GSM2204392 | 28460002; |
| SRR964946_alt | HEK293 | WT | SRR964946 | 22927429; |
Literature information
| PMID | 26687005; |
| Cell lines Or Tissues | BJ |
| Phenotype | NULL |
| Gene ID | ENSG00000148187 |
| Transcript ID | ENST00000546115 |
| Symbol | NA |
| ORF Type | sORF |
| Gene Type | protein_coding |
| Throughput | High-throughput Literature Mining |
| Interaction | NA |
| Function Description | NA |
Mass Spectrometry Information
Function and Disease
| Functional domain prediction |  |
| Analysis | Signature Accession | Signature Description | Start location | Stop location | Score | Status of the match | InterPro accession | InterPro description | GO | Pathways |
|---|
| No results |
| Disease | Detected |
|---|
| No results |
Related Variants
| Variant ID | Consequence to sORF | rsID | Ribo-seq ID |
|---|
| 9-122264840-A-C | Non-Synonymous p.S49R | rs7035313 | SRR3680969 |
Related Small Proteins with Different TISs
| SmProt ID | Small Protein Length | Start Codon | Strand | Blocks |
|---|
| SPROHSA337423 | 44 | GTG | + | 122264731-122264866 |
SmProt