Specific Information of Small Protein : SPROHSA142534
General Information
Small Protein IDSPROHSA142534
Organismhuman (Homo sapiens)
Small Protein SequenceMKAEMPGAHEHPSVALDGTSCWATQLKCG*
RNA SequenceatgaaggcagaaatgcctggggcccacgaacatcccagtgtggccctgGACGGGACATCATGCTGGGCAACACAGCTAAAATGCGGGTGA
Protein Length29
Start Codonatg
Locationchr15:57307553-57307643:+
Blocks57307553-57307643
Mean PhyloCSF-8.1941333135
Data SourceRibosome profiling;
Related GenesENSG00000247982; LINC00926; NONHSAG016995;
Ribosome profiling
RiboIDGeneIDTransIDSymbolGeneTypeTISTypeRiboPvalueTISPvalueStartOnTransStopOnTrans
GSE94613_2ENSG00000247982.6ENST00000613170.1LINC00926lncRNANovel0.00713None12541344
GSE94613_2ENSG00000247982.6ENST00000502027.1LINC00926lncRNANovel0.00713None19362026
Min Ribo Pvalue0.00713
Min TIS PvalueNone
RiboIDCellORTissuePhenotypeRiboSourcePMID
GSE94613_2MOLM13acute myeloid leukemiaGSM248105329186125;

Database information
No results
Literature information
No results
Mass Spectrometry Information
No results
Function and Disease
Functional domain prediction Funtion   
AnalysisSignature AccessionSignature DescriptionStart locationStop locationScoreStatus of the matchInterPro accessionInterPro descriptionGOPathways
No results
DiseaseDetected
acute myeloid leukemiaPredictedByRibo
Related Variants
VarIDConsequence To sORFrsIDRiboID
No results
Related Small Proteins with Different TISs
IDSmall Protein LengthStart CodonStrandBlocks
SPROHSA3108228aag+57307556-57307643
SPROHSA13592558ATC+57306993-57307068,57307541-57307643
SPROHSA15762292ATG+57306891-57307068,57307541-57307643
References
PMID29186125
TitlePromoter-bound METTL3 maintains myeloid leukaemia by m 6 A-dependent translation control
JournalNature.2017 Dec 7;552(7683):126-131.doi: 10.1038/nature24678.Epub 2017 Nov 27.
AuthorsIsaia Barbieri,Konstantinos Tzelepis,Luca Pandolfini,Junwei Shi,Gonzalo Millán-Zambrano,Samuel C Robson,Demetrios Aspris,Valentina Migliori,Andrew J Bannister,Namshik Han,Etienne De Braekeleer,Hannes Ponstingl,Alan Hendrick,Christopher R Vakoc,George S Vassiliou,Tony Kouzarides