| General Information |
| Family ID | 19 |
| No. Members | 784 |
| Small Protein Length | 50 |
| Representative AA Seq (detail) | MNEKIFKTIRGTGAASLAVGIVVLVTGISAGVMMIVNGARLLKCKSQVLI |
| Representative DNA Seq (detail) | ATGAACGAAAAAATTTTTAAGACAATAAGAGGTACCGGTGCGGCAAGTCTCGCAGTCGGGATCGTGGTTCTGGTAACCGGAATTTCAGCCGGCGTGATGATGATCGTAAACGGTGCAAGACTTCTGAAGTGTAAAAGTCAGGTATTGATTTAG |
| Example of a Refseq homolog | WP_004843492.1 |
| Associated HGT genes | INT_C_like_5, HTH_MerR-trunc, zf-IS66, RecA, INT_ICEBs1_C_like, recomb_XerD, INT_P4_C, Rad51_DMC1_radA, PRK09870, XerD, INT_XerDC_C, INT_RitA_C_like, DEDD_Tnp_IS110, INT_FimBE_like, Integrase_DNA, INT_Rci_Hp1_C, INT_IntI_C, RecA-like_NTPases, LZ_Tnp_IS66, INT_C_like_1, recomb_XerC, Phage_integrase, INT_RitB_C_like, XerC, Phage_int_SAM_3, DNA_BRE_C, xerC, INTN1_C_like, Transposase_20, INT_RitC_C_like |
| Number of non bacterial | 0 |
| Non bacterial classification_numbe of members that were classified to it | NA |
| RNA code p-value assigned to family | 0 |
| number of species | 54 |
| Species | Roseburia intestinalis_96, Blautia sp. CAG:257_4, Bacteroides ovatus_1, Roseburia sp. CAG:18_43_25_28, Clostridiales bacterium 42_27_1, Roseburia sp. CAG:182_5, Roseburia sp. 40_7_1, Azospirillum sp. 51_20_1, Roseburia inulinivorans CAG:15_6, Ruminococcus sp. CAG:9_1, Eubacterium sp. 38_16_1, Ruminococcus bicirculans_1, Dorea sp. 42_8_1, Butyrivibrio sp. CAG:318_1, Clostridium sp. CAG:264_1, Unclassified_8, Clostridium sp. CAG:81_1, Dorea longicatena_11, butyrate-producing bacterium SS3/4_13, Firmicutes bacterium CAG:56_42, Ruminococcus sp. CAG:60_1, Roseburia sp. CAG:18_24, Faecalibacterium sp. UBA2087_1, Ruminococcus obeum CAG:39_1, Merdimonas faecis_3, Roseburia inulinivorans_112, Ruminococcus sp. 5_1_39BFAA_3, Firmicutes bacterium CAG:24_122, Coprococcus catus_1, Roseburia intestinalis CAG:13_8, Blautia sp. Marseille-P3087_2, Roseburia sp. CAG:197_2, Blautia sp. UBA2945_3, Ruminococcus sp. Marseille-P328_19, Firmicutes bacterium CAG:227_1, Clostridium sp. Marseille-P3244_1, Roseburia faecis_59, Eubacterium sp. CAG:146_1, Parabacteroides merdae_1, Blautia wexlerae_23, Clostridium sp. CAG:58_4, Ruminococcus lactaris_1, Dorea formicigenerans_1, [Eubacterium] hallii_10, Blautia sp. Marseille-P2398_4, Ruminococcus sp. CAG:108_1, Roseburia hominis_31, Dorea longicatena CAG:42_9, Blautia sp. CAG:237_9, Roseburia sp. CAG:197_41_10_2, Firmicutes bacterium CAG:424_1, Roseburia sp. CAG:471_1, Eubacterium hallii CAG:12_2, Firmicutes bacterium CAG:95_19, Clostridiales bacterium Nov_37_41_4 |
| Sample Origin |
| Body Sites | No. Samples | Fraction |
| Mouth | 1 | 0.004524887 |
| Skin | 1 | 0.034482759 |
| Vagina | 0 | 0 |
| Gut | 190 | 0.769230769 |
| Number of homologs from non-human metagenomes | Number of different types of non-human environments | Non human environments in which homologs exist_number of homologs |
| 20 | 4 | Mammals_17, Fungi_1, Bioreactor_1, Aquatic_1 |
| Function prediction |
| % of family members that are predicted to have a transmembrane domain (TMHMM) | 1 | ||
| Is family classified as Transmembrane (TMHMM) | 1 | ||
| % of family members that are predicted to have a signal peptide in gram+ (SignalP_v5.0) | 0.024234694 | ||
| Is family predicted to be secreted in gram+ (SignalP_v5.0) | 0 | ||
| % of family members that are predicted to have a signal peptide in gram- (SignalP_v5.0) | 0 | ||
| Is family predicted to be secreted in gram- (SignalP_v5.0) | 0 | ||
| Number of members the are transmembrane (Phobius) | 784 | ||
| Fraction of members that are transmembrane (Phobius) | 1 | ||
| Number of members that are secreted (Phobius) | 0 | ||
| Fraction of members that are secreted (Phobius) | 0 | ||
| Number of significant complete CDD hits that were assigned to family representative sequence | 0 | ||
| PSSMs assigned | NA | ||
| Domains assigned | NA | ||
| References |
| PubMed ID | 31402174 |
| Title | Large-Scale Analyses of Human Microbiomes Reveal Thousands of Small, Novel Genes |
| Authors | Hila Sberro, Brayon J. Fremin, Soumaya Zlitni, Fredrik Edfors, Nicholas Greenfield, Michael P. Snyder, Georgios A. Pavlopoulos, Nikos C. Kyrpides, and Ami S. Bhatt |
| Journal | Cell 178, 1–15, August 22, 2019 |