SmProt

Specific Information of Small Protein : SPROHSA316610

General Information

Small Protein ID	SPROHSA316610
Organism	Human (Homo sapiens)
Small Protein Sequence	LFQEHQFEALGLLILLRLWRVARIINGIIISVKTRSERQLLRLKQMNVQLAAKIQHLEFSCSEKPLD*
RNA Sequence	CTGTTCCAGGAGCACCAGTTTGAGGCTCTGGGCCTGCTGATTCTGCTCCGGCTGTGGCGGGTGGCCCGGATCATCAATGGGATTATCATCTCAGTTAAGACACGTTCAGAACGGCAACTCTTAAGGTTAAAACAGATGAATGTACAATTGGCCGCCAAGATTCAACACCTTGAGTTCAGCTGCTCTGAGAAGCCCCTGGACTGA
Protein Length	67
Start Codon	CTG
Location	chr12:110628164-110651295:-
Blocks	110628164-110628176,110650167-110650280,110651216-110651295
Mean PhyloCSF	5.77991666937
Data Source	Ribosome profiling;
Related Genes	ENSG00000204852; TCTN1; ENSG00000122986; HVCN1;
Mass (Da)	mono. 7862.4; avg. 7867.3

Ribosome profiling

Ribo-seq ID	Ensembl Gene ID	Ensembl Transcript ID	Symbol	Gene Type	TIS Type	Ribo P value	TIS P value	Start On Trans	Stop On Trans	In-frame Count	Ribo-seq RPKM
GSE81802_alt	ENSG00000122986.13	ENST00000548312.5	HVCN1	Protein_coding	Truncated	0.009279	0.041309	773	977	NA	NA

Min Ribo P value	0.009279
Min TIS P value	0.041309

Ribo-seq ID	Cell or Tissue	Phenotype	Ribo-seq Source Details	PMID
GSE81802_alt	CD19+ B cells	WT	GSM2175737	29529302;

Database information

No results

Literature information

No results

Mass Spectrometry Information

No results

Function and Disease

Functional domain prediction

Analysis	Signature Accession	Signature Description	Start location	Stop location	Score	Status of the match	InterPro accession	InterPro description	GO	Pathways
Pfam	PF16799	C-terminal membrane-localisation domain of ion-channel, VCN1	38	64	1.6E-15	T	IPR031844	Voltage-gated hydrogen channel 1, C-terminal membrane-localisation domain		Reactome: R-HSA-1222556\|Reactome: R-HSA-1300642\|Reactome: R-HSA-6798695
Gene3D	G3DSA:1.20.5.170		28	67	1.1E-19	T
PANTHER	PTHR46480		3	64	1.2E-19	T	IPR031846	Voltage-gated hydrogen channel 1	GO:0005887\|GO:0030171\|GO:1902600	Reactome: R-HSA-1222556\|Reactome: R-HSA-1300642\|Reactome: R-HSA-6798695

Disease	Detected
No results

Related Variants

Variant ID	Consequence to sORF	rsID	Ribo-seq ID
12-110650222-C-G	Non-Synonymous p.M46I	.	SRR5239057

Related Small Proteins with Different TISs

SmProt ID	Small Protein Length	Start Codon	Strand	Blocks
No results