SmProt

Specific Information of Small Protein : SPROHSA209581

General Information

Small Protein ID	SPROHSA209581
Organism	Human (Homo sapiens)
Small Protein Sequence	MVLLEKKSATYFQVLLCCLILLQRLLQEQRLKTHSELDHINAQYLEVKCGAMILKLRMEELNILSNTLLRKWKFIVRLGTVWRERFTYGSSTWRSQDRS*
RNA Sequence	ATGGTGCTGCTGGAGAAGAAGAGTGCCACCTACTTCCAGGTGCTTCTCTGCTGCCTCATTTTGCTGCAGAGGCTTCTTCAGGAACAACGGCTGAAGACTCACTCCGAGTTAGACCACATCAATGCCCAGTACCTGGAAGTCAAGTGTGGTGCTATGATACTTAAGCTGAGGATGGAAGAGTTAAATATTTTGTCCAACACACTGCTGAGAAAGTGGAAGTTCATTGTCCGATTAGGGACCGTTTGGAGGGAGCGATTCACCTACGGGAGCAGCACATGGAGAAGTCAAGACAGGTCCTGA
Protein Length	99
Start Codon	ATG
Location	chr1:170369339-170369639:-
Blocks	170369339-170369639
Mean PhyloCSF	0
Data Source	Ribosome profiling;
Related Genes	ENSG00000226967; HAUS4P1; NONHSAG003427;
Mass (Da)	mono. 11837.4; avg. 11844.9

Ribosome profiling

Ribo-seq ID	Ensembl Gene ID	Ensembl Transcript ID	Symbol	Gene Type	TIS Type	Ribo P value	TIS P value	Start On Trans	Stop On Trans	In-frame Count	Ribo-seq RPKM
GSE105082	ENSG00000226967.1	ENST00000406739.2	HAUS4P1	Processed_pseudogene	Novel	0.003845	None	728	1028	7	1.58561264

Min Ribo P value	0.003845
Min TIS P value	None

Ribo-seq ID	Cell or Tissue	Phenotype	Ribo-seq Source Details	PMID
GSE105082	HELA	Cervical cancer	GSM2817679; GSM2817680	30591072;

Database information

No results

Literature information

No results

Mass Spectrometry Information

No results

Function and Disease

Functional domain prediction

Analysis	Signature Accession	Signature Description	Start location	Stop location	Score	Status of the match	InterPro accession	InterPro description	GO	Pathways
Pfam	PF14735	HAUS augmin-like complex subunit 4	2	67	6.7E-19	T	IPR029327	HAUS augmin-like complex subunit 4	GO:0051225\|GO:0070652	Reactome: R-HSA-2565942\|Reactome: R-HSA-380259\|Reactome: R-HSA-380270\|Reactome: R-HSA-380284\|Reactome: R-HSA-380320\|Reactome: R-HSA-5620912\|Reactome: R-HSA-8854518
PANTHER	PTHR16219		1	67	7.7E-22	T	IPR029327	HAUS augmin-like complex subunit 4	GO:0051225\|GO:0070652	Reactome: R-HSA-2565942\|Reactome: R-HSA-380259\|Reactome: R-HSA-380270\|Reactome: R-HSA-380284\|Reactome: R-HSA-380320\|Reactome: R-HSA-5620912\|Reactome: R-HSA-8854518
PRINTS	PR02090	HAUS augmin-like complex subunit 4 signature	21	39	1.1E-15	T	IPR026214	HAUS augmin-like complex subunit 4, metazoa	GO:0007098\|GO:0051225\|GO:0070652	Reactome: R-HSA-2565942\|Reactome: R-HSA-380259\|Reactome: R-HSA-380270\|Reactome: R-HSA-380284\|Reactome: R-HSA-380320\|Reactome: R-HSA-5620912\|Reactome: R-HSA-8854518
PRINTS	PR02090	HAUS augmin-like complex subunit 4 signature	44	61	1.1E-15	T	IPR026214	HAUS augmin-like complex subunit 4, metazoa	GO:0007098\|GO:0051225\|GO:0070652	Reactome: R-HSA-2565942\|Reactome: R-HSA-380259\|Reactome: R-HSA-380270\|Reactome: R-HSA-380284\|Reactome: R-HSA-380320\|Reactome: R-HSA-5620912\|Reactome: R-HSA-8854518

Disease	Detected
Cervical cancer	Predicted by Ribo-seq

Related Variants

Variant ID	Consequence to sORF	rsID	Ribo-seq ID
1-170369411-G-A	Stop Gain p.R77*	.	SRR5227296; SRR5239058; SRR1333393; SRR1333394; SRR627627
1-170369415-A-G	Synonymous p.I75I	.	SRR5227296; SRR5239058; SRR1333394; SRR627627
1-170369481-T-G	Synonymous p.I53I	.	SRR5239051; SRR5239057; SRR627622; SRR627626; SRR810100
1-170369493-A-G	Synonymous p.C49C	.	SRR810100

Related Small Proteins with Different TISs

SmProt ID	Small Protein Length	Start Codon	Strand	Blocks
No results