SmProt

Specific Information of Small Protein : SPROHSA209021

General Information

Small Protein ID	SPROHSA209021
Organism	Human (Homo sapiens)
Small Protein Sequence	MVSSDDELLSRDRDVYVTTHTSRNTRDEGAIGLRPSGTVGCPICMDRYSEIVQNRRLIVSTECGHVFCSQCLRDSLKNANTCPTCRKKINHKQYHSIHI*
RNA Sequence	ATGGTGAGCAGTGACGATGAGTTGTTGTCCAGGGACAGAGACGTGTATGTGACTACCCACACTTCCAGAAACACCAGGGATGAGGGCGCTATAGGCCTCAGGCCCTCGGGTACTGTCGGTTGTCCTATCTGCATGGACAGATATTCAGAGATCGTGCAGAATAGACGTCTCATCGTTTCCACAGAATGTGGCCATGTCTTCTGTAGCCAGTGCCTCCGTGATTCCCTGAAGAACGCTAATACTTGCCCAACTTGTAGGAAAAAGATCAACCACAAACAGTACCACTCCATTCATATATGA
Protein Length	99
Start Codon	ATG
Location	chr1:231021883-231022183:+
Blocks	231021883-231022183
Mean PhyloCSF	0
Data Source	Ribosome profiling;
Related Genes	ENSG00000182118; FAM89A; ENSG00000227934; AL732414.1;
Mass (Da)	mono. 11232.5; avg. 11239.6

Ribosome profiling

Ribo-seq ID	Ensembl Gene ID	Ensembl Transcript ID	Symbol	Gene Type	TIS Type	Ribo P value	TIS P value	Start On Trans	Stop On Trans	In-frame Count	Ribo-seq RPKM
SRR2991181	ENSG00000227934.1	ENST00000413346.1	AL732414.1	Processed_pseudogene	Novel	0.002316	None	273	573	49	26.6964708

Min Ribo P value	0.002316
Min TIS P value	None

Ribo-seq ID	Cell or Tissue	Phenotype	Ribo-seq Source Details	PMID
SRR2991181	SH-SY5Y	Neuroblastoma	GSM1970518	31109297;

Database information

No results

Literature information

No results

Mass Spectrometry Information

No results

Function and Disease

Functional domain prediction

Analysis	Signature Accession	Signature Description	Start location	Stop location	Score	Status of the match	InterPro accession	InterPro description
ProSiteProfiles	PS50089	Zinc finger RING-type profile.	41	86	13.389	T	IPR001841	Zinc finger, RING-type
PANTHER	PTHR23041:SF67		2	99	1.5E-58	T
Pfam	PF13639	Ring finger domain	41	86	5.6E-11	T	IPR001841	Zinc finger, RING-type
CDD	cd16533	RING-HC_RNF4	36	89	2.96071E-25	T
PANTHER	PTHR23041		2	99	1.5E-58	T
SMART	SM00184		41	85	3.4E-9	T	IPR001841	Zinc finger, RING-type
ProSitePatterns	PS00518	Zinc finger RING-type signature.	63	72	-	T	IPR017907	Zinc finger, RING-type, conserved site
SUPERFAMILY	SSF57850		40	92	2.29E-18	T
Gene3D	G3DSA:3.30.40.10		37	99	1.4E-19	T	IPR013083	Zinc finger, RING/FYVE/PHD-type

Disease	Detected
Neuroblastoma	Predicted by Ribo-seq

Related Variants

Variant ID	Consequence to sORF	rsID	Ribo-seq ID
1-231021975-T-C	Non-Synonymous p.I31T	rs4311872	SRR5047770; SRR5047771; SRR5512738; SRR8907185; SRR3680966; SRR3680967; SRR3680968; SRR1795425
1-231022022-A-G	Non-Synonymous p.R47G	.	SRR3208921; SRR5239057
1-231022027-T-C	Synonymous p.Y48Y	.	SRR3208921; SRR5239057
1-231022046-A-G	Non-Synonymous p.R55G	.	SRR5047770; SRR5047771; SRR5047772; SRR5227294; SRR5227296; SRR5382424; SRR6053334; SRR3680967; SRR3680969

Related Small Proteins with Different TISs

SmProt ID	Small Protein Length	Start Codon	Strand	Blocks
No results