Specific Information of Small Protein : SPROHSA145932
General Information
Small Protein IDSPROHSA145932
Organismhuman (Homo sapiens)
Small Protein SequenceMTDSSARTEALSILYPAVR*
RNA SequenceATGACAGACagctctgcaagaacggaggccctgtctattttgtacccagctgtacgTTAA
Protein Length19
Start CodonATG
Locationchr2:174396175-174398278:+
Blocks174396175-174396231,174398274-174398278
Mean PhyloCSF-5.7321166118
Data SourceRibosome profiling;
Related GenesENSG00000144306; SCRN3; NONHSAG077962;
Ribosome profiling
RiboIDGeneIDTransIDSymbolGeneTypeTISTypeRiboPvalueTISPvalueStartOnTransStopOnTrans
SRR5047771ENSG00000144306.14ENST00000427038.5SCRN3protein_coding5'UTR0.009936None368428
GSE94613_2ENSG00000144306.14ENST00000427038.5SCRN3protein_coding5'UTR0.009936None368428
GSE94613_2_altENSG00000144306.14ENST00000427038.5SCRN3protein_coding5'UTR0.009936None368428
Min Ribo Pvalue0.009936
Min TIS PvalueNone
RiboIDCellORTissuePhenotypeRiboSourcePMID
GSE94613_2MOLM13acute myeloid leukemiaGSM248105329186125;
GSE94613_2_altMOLM13acute myeloid leukemiaGSM248105329186125;
SRR5047771iPSC-differentiated dopamine neuronsParkinson DiseaseNANA;

Database information
No results
Literature information
No results
Mass Spectrometry Information
No results
Function and Disease
Functional domain prediction Funtion   
AnalysisSignature AccessionSignature DescriptionStart locationStop locationScoreStatus of the matchInterPro accessionInterPro descriptionGOPathways
No results
DiseaseDetected
acute myeloid leukemiaPredictedByRibo
Related Variants
VarIDConsequence To sORFrsIDRiboID
2-174396181-A-TSynonymous p.T2Trs79355383SRR5239057;SRR5239058
Related Small Proteins with Different TISs
IDSmall Protein LengthStart CodonStrandBlocks
No results
References
PMID29186125
TitlePromoter-bound METTL3 maintains myeloid leukaemia by m 6 A-dependent translation control
JournalNature.2017 Dec 7;552(7683):126-131.doi: 10.1038/nature24678.Epub 2017 Nov 27.
AuthorsIsaia Barbieri,Konstantinos Tzelepis,Luca Pandolfini,Junwei Shi,Gonzalo Millán-Zambrano,Samuel C Robson,Demetrios Aspris,Valentina Migliori,Andrew J Bannister,Namshik Han,Etienne De Braekeleer,Hannes Ponstingl,Alan Hendrick,Christopher R Vakoc,George S Vassiliou,Tony Kouzarides