Specific Information of Small Protein : SPROHSA145298
General Information
Small Protein IDSPROHSA145298
Organismhuman (Homo sapiens)
Small Protein SequenceMTTCS*
RNA SequenceATGACAACATGCAGCTGA
Protein Length5
Start CodonATG
Locationchr6:136784247-136784265:+
Blocks136784247-136784265
Mean PhyloCSF-7.88516660531
Data SourceRibosome profiling;
Related GenesENSG00000197442; MAP3K5; ENSG00000286646; AL121933.1; NONHSAG093642;
Ribosome profiling
RiboIDGeneIDTransIDSymbolGeneTypeTISTypeRiboPvalueTISPvalueStartOnTransStopOnTrans
GSE94613_1ENSG00000286646.1ENST00000661159.1AL121933.1lncRNANovel0.007488None203221
GSE94613_1_altENSG00000286646.1ENST00000661159.1AL121933.1lncRNANovel0.007488None203221
Min Ribo Pvalue0.007488
Min TIS PvalueNone
RiboIDCellORTissuePhenotypeRiboSourcePMID
GSE94613_1MOLM13acute myeloid leukemiaGSM248105229186125;
GSE94613_1_altMOLM13acute myeloid leukemiaGSM248105229186125;

Database information
No results
Literature information
No results
Mass Spectrometry Information
No results
Function and Disease
Functional domain prediction Funtion   
AnalysisSignature AccessionSignature DescriptionStart locationStop locationScoreStatus of the matchInterPro accessionInterPro descriptionGOPathways
No results
DiseaseDetected
acute myeloid leukemiaPredictedByRibo
Related Variants
VarIDConsequence To sORFrsIDRiboID
6-136784262-C-TSynonymous p.S5Srs9483947SRR5239050;SRR5239051;SRR5239052;SRR5239056;SRR5239057;SRR5239058
Related Small Proteins with Different TISs
IDSmall Protein LengthStart CodonStrandBlocks
No results
References
PMID29186125
TitlePromoter-bound METTL3 maintains myeloid leukaemia by m 6 A-dependent translation control
JournalNature.2017 Dec 7;552(7683):126-131.doi: 10.1038/nature24678.Epub 2017 Nov 27.
AuthorsIsaia Barbieri,Konstantinos Tzelepis,Luca Pandolfini,Junwei Shi,Gonzalo Millán-Zambrano,Samuel C Robson,Demetrios Aspris,Valentina Migliori,Andrew J Bannister,Namshik Han,Etienne De Braekeleer,Hannes Ponstingl,Alan Hendrick,Christopher R Vakoc,George S Vassiliou,Tony Kouzarides