Specific Information of Small Protein : SPROHSA141390
General Information
Small Protein IDSPROHSA141390
Organismhuman (Homo sapiens)
Small Protein SequenceMKQHARPGTSPAPASGLEGQGRGPGGRRGLWSSPSARVVARNGDRARARSLLPAPPRPRVFLPRDSERPLLQARLAAGR*
RNA SequenceATGAAGCAACATGCTAGGCCCGGGACAAGTCCGGCTCCGGCCTCGGGTCTGGAGGGACAAGGCCGGGGGCCGGGTGGCAGACGGGGCCTCTGGTCTTCCCCCAGCGCGAGGGTCGTGGCGCGAAACGGGGACAGGGCGCGCGCTCGGAGCCTCCTCCCCGCCCCGCCCCGCCCAAGGGTCTTCCTCCCCCGGGATTCAGAGCGGCCCCTCCTCCAGGCCAGGCTCGCCGCGGGGCGCTGA
Protein Length79
Start CodonATG
Locationchr1:244970112-244970352:+
Blocks244970112-244970352
Mean PhyloCSF-5.51705959544
Data SourceRibosome profiling;
Related GenesENSG00000203666; EFCAB2; ENSG00000272195; AL356512.1; NONHSAG105240;NONHSAG004873;
Ribosome profiling
RiboIDGeneIDTransIDSymbolGeneTypeTISTypeRiboPvalueTISPvalueStartOnTransStopOnTrans
GSE94613_2ENSG00000203666.12ENST00000366522.6EFCAB2protein_coding5'UTR0.007116None131371
GSE94613_2_altENSG00000203666.12ENST00000366522.6EFCAB2protein_coding5'UTR0.007116None131371
Min Ribo Pvalue0.007116
Min TIS PvalueNone
RiboIDCellORTissuePhenotypeRiboSourcePMID
GSE94613_2MOLM13acute myeloid leukemiaGSM248105329186125;
GSE94613_2_altMOLM13acute myeloid leukemiaGSM248105329186125;

Database information
No results
Literature information
No results
Mass Spectrometry Information
No results
Function and Disease
Functional domain prediction Funtion   
AnalysisSignature AccessionSignature DescriptionStart locationStop locationScoreStatus of the matchInterPro accessionInterPro descriptionGOPathways
MobiDBLitemobidb-liteconsensus disorder prediction167-T
DiseaseDetected
acute myeloid leukemiaPredictedByRibo
Related Variants
VarIDConsequence To sORFrsIDRiboID
No results
Related Small Proteins with Different TISs
IDSmall Protein LengthStart CodonStrandBlocks
No results
References
PMID29186125
TitlePromoter-bound METTL3 maintains myeloid leukaemia by m 6 A-dependent translation control
JournalNature.2017 Dec 7;552(7683):126-131.doi: 10.1038/nature24678.Epub 2017 Nov 27.
AuthorsIsaia Barbieri,Konstantinos Tzelepis,Luca Pandolfini,Junwei Shi,Gonzalo Millán-Zambrano,Samuel C Robson,Demetrios Aspris,Valentina Migliori,Andrew J Bannister,Namshik Han,Etienne De Braekeleer,Hannes Ponstingl,Alan Hendrick,Christopher R Vakoc,George S Vassiliou,Tony Kouzarides