Specific Information of Small Protein : SPROHSA136188
General Information
Small Protein IDSPROHSA136188
Organismhuman (Homo sapiens)
Small Protein SequenceMKKTFLLTVNGNVSIHPT
RNA SequenceATGAAAAAAACCTTCCTCTTGACGGTAAACGGCAACGTTTCCATTCACCCCACC
Protein Length18
Start CodonATG
Locationchr5:79623262-79623316:+
Blocks79623262-79623316
Mean PhyloCSF-7.41533332401
Data SourceRibosome profiling;
Related GenesENSG00000164329; TENT2; NONHSAG040825;
Ribosome profiling
RiboIDGeneIDTransIDSymbolGeneTypeTISTypeRiboPvalueTISPvalueStartOnTransStopOnTrans
GSE123564_2ENSG00000164329.13ENST00000503620.1TENT2protein_codingNovel0.047495None528582
GSE123564_2_altENSG00000164329.13ENST00000503620.1TENT2protein_codingNovel0.047495None528582
Min Ribo Pvalue0.047495
Min TIS PvalueNone
RiboIDCellORTissuePhenotypeRiboSourcePMID
GSE123564_2Skin fibroblasts: Hbs1L-deficientfacial dysmorphism, growth restriction and retinal depositsGSM3507223;GSM3507224;GSM3507225;GSM3507228;GSM3507229;GSM350723030707697;
GSE123564_2_altSkin fibroblasts: Hbs1L-deficientfacial dysmorphism, growth restriction and retinal depositsGSM3507223;GSM3507224;GSM3507225;GSM3507228;GSM3507229;GSM350723030707697;

Database information
No results
Literature information
No results
Mass Spectrometry Information
No results
Function and Disease
Functional domain prediction Funtion   
AnalysisSignature AccessionSignature DescriptionStart locationStop locationScoreStatus of the matchInterPro accessionInterPro descriptionGOPathways
No results
DiseaseDetected
No results
Related Variants
VarIDConsequence To sORFrsIDRiboID
No results
Related Small Proteins with Different TISs
IDSmall Protein LengthStart CodonStrandBlocks
No results
References
PMID30707697
TitleMammalian Hbs1L deficiency causes congenital anomalies and developmental delay associated with Pelota depletion and 80S monosome accumulation
JournalPLoS Genet.2019 Feb 1;15(2):e1007917.doi: 10.1371/journal.pgen.1007917.eCollection 2019 Feb.
AuthorsAmy E O'Connell,Maxim V Gerashchenko,Marie-Francoise O'Donohue,Samantha M Rosen,Eric Huntzinger,Diane Gleeson,Antonella Galli,Edward Ryder,Siqi Cao,Quinn Murphy,Shideh Kazerounian,Sarah U Morton,Klaus Schmitz-Abe,Vadim N Gladyshev,Pierre-Emmanuel Gleizes,Bertrand Séraphin,Pankaj B Agrawal