NPInter v5.0

Documents functional interactions between noncoding RNAs and biomolecules

Examples: MALAT1, hsa-mir-107, NONHSAG008675, MI0000114, P04637

LZTR1

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Molecule Information

Alias

-

Class

mRNA

Ensembl id

ENSG00000099949

Organism

Homo sapiens

Description

Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex that mediates ubiquitination of Ras (K-Ras/KRAS, N-Ras/NRAS and H-Ras/HRAS), leading to inhibit Ras signaling by decreasing Ras association with membranes (PubMed:30442762, PubMed:30442766). Probably mediates non- degradative ubiquitination of Ras (PubMed:30442762).

Interaction Information
Interaction ID Interact With Tissue or Cell line Pubmed Data source
Disease Annotation
Disease Name Data Source PubMed
noonan syndrome eDGAR Database
schwannomatosis eDGAR Database