Alias

-

Class

mRNA

Ensembl id

ENSG00000115806

Organism

Homo sapiens

Description

Plays a role in the assembly and membrane stacking of the Golgi cisternae, and in the process by which Golgi stacks reform after breakdown during mitosis and meiosis (PubMed:10487747, PubMed:21515684, PubMed:22523075). May regulate the intracellular transport and presentation of a defined set of transmembrane proteins, such as transmembrane TGFA (PubMed:11101516). Required for normal acrosome formation during spermiogenesis and normal male fertility, probably by promoting colocalization of JAM2 and JAM3 at contact sites between germ cells and Sertoli cells (By similarity). Mediates ER stress- induced unconventional (ER/Golgi-independent) trafficking of core- glycosylated CFTR to cell membrane (PubMed:21884936, PubMed:27062250, PubMed:28067262).