Interaction Profile
Interaction ID
ncRI-40984233
Interaction Molecules
hsa-miR-505-3p -- LZTR1
Interaction Level
RNA-RNA
Interaction Class
binding
Data Source
RISE database
Tags
Organism
Homo sapiens
Tissue or Cell Type
HEK293
Experiment
CLASH
Description
RNA-RNA interaction from RISE database
Molecule Profile
Alias
hsa-miR-505-5p;hsa-miR-505;MIR505
Class
miRNA
miRBase id
Description
Homo sapiens miR-505 stem-loop
Alias
-
Class
mRNA
Ensembl id
ENSG00000099949
Description
Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex that mediates ubiquitination of Ras (K-Ras/KRAS, N-Ras/NRAS and H-Ras/HRAS), leading to inhibit Ras signaling by decreasing Ras association with membranes (PubMed:30442762, PubMed:30442766). Probably mediates non- degradative ubiquitination of Ras (PubMed:30442762).
Reference Information
| Pubmed ID | 23622248 | Journal | Cell |
|---|---|---|---|
| Title | Mapping the human miRNA interactome by CLASH reveals frequent noncanonical binding. | ||
| Author | Helwak A, Kudla G, Dudnakova T, Tollervey D | ||
Network View
Disease Annotation
| Molecule | Disease | Data Source |
|---|---|---|
| hsa-miR-505-3p | acute myeloid leukemia | MNDR Database |
| hsa-miR-505-3p | acute T cell leukemia | MNDR Database |
| hsa-miR-505-3p | Adenoviridae Infections | MNDR Database |
| hsa-miR-505-3p | Alzheimer's disease | MNDR Database |
| hsa-miR-505-3p | amyotrophic lateral sclerosis | MNDR Database |
| hsa-miR-505-3p | arthritis | MNDR Database |
| hsa-miR-505-3p | bladder urothelial carcinoma | MNDR Database |
| hsa-miR-505-3p | bone disease | MNDR Database |
| hsa-miR-505-3p | brain disease | MNDR Database |
| hsa-miR-505-3p | breast cancer | MNDR Database |
| hsa-miR-505-3p | Breast Neoplasms | MNDR Database |
| hsa-miR-505-3p | cancer | MNDR Database |
| hsa-miR-505-3p | carcinoma | MNDR Database |
| hsa-miR-505-3p | Carcinoma, Ductal, Breast | MNDR Database |
| hsa-miR-505-3p | Carcinoma, Renal Cell | MNDR Database |
| hsa-miR-505-3p | cervical squamous cell carcinoma | MNDR Database |
| hsa-miR-505-3p | cholangiocarcinoma | MNDR Database |
| hsa-miR-505-3p | colon adenocarcinoma | MNDR Database |
| hsa-miR-505-3p | colon cancer | MNDR Database |
| hsa-miR-505-3p | colorectal cancer | MNDR Database |
| hsa-miR-505-3p | diabetes mellitus | MNDR Database |
| hsa-miR-505-3p | endometrial cancer | MNDR Database |
| hsa-miR-505-3p | esophageal cancer | MNDR Database |
| hsa-miR-505-3p | eye disease | MNDR Database |
| hsa-miR-505-3p | familiar ovarian carcinoma | MNDR Database |
| hsa-miR-505-3p | Friedreich ataxia | MNDR Database |
| hsa-miR-505-3p | Gait Ataxia | MNDR Database |
| hsa-miR-505-3p | Glioblastoma | MNDR Database |
| hsa-miR-505-3p | Graves' disease | MNDR Database |
| hsa-miR-505-3p | head and neck squamous cell carcinoma | MNDR Database |
| hsa-miR-505-3p | hepatocellular carcinoma | MNDR Database |
| hsa-miR-505-3p | Her2-receptor positive breast cancer | MNDR Database |
| hsa-miR-505-3p | Hodgkin's lymphoma | MNDR Database |
| hsa-miR-505-3p | hypersensitivity reaction type II disease | MNDR Database |
| hsa-miR-505-3p | hypertension | MNDR Database |
| hsa-miR-505-3p | intellectual disability | MNDR Database |
| hsa-miR-505-3p | intracranial aneurysm | MNDR Database |
| hsa-miR-505-3p | intrahepatic cholangiocarcinoma | MNDR Database |
| hsa-miR-505-3p | leukemia | MNDR Database |
| hsa-miR-505-3p | liposarcoma | MNDR Database |
| hsa-miR-505-3p | Liver Neoplasms | MNDR Database |
| hsa-miR-505-3p | lung adenocarcinoma | MNDR Database |
| hsa-miR-505-3p | lung cancer | MNDR Database |
| hsa-miR-505-3p | lung disease | MNDR Database |
| hsa-miR-505-3p | lung small cell carcinoma | MNDR Database |
| hsa-miR-505-3p | lung squamous cell carcinoma | MNDR Database |
| hsa-miR-505-3p | lymphoma | MNDR Database |
| hsa-miR-505-3p | malignant glioma | MNDR Database |
| hsa-miR-505-3p | malignant pleural mesothelioma | MNDR Database |
| hsa-miR-505-3p | middle cerebral artery infarction | MNDR Database |
| hsa-miR-505-3p | multiple myeloma | MNDR Database |
| hsa-miR-505-3p | Multiple Sclerosis, Chronic Progressive | MNDR Database |
| hsa-miR-505-3p | Myasthenia Gravis, Autoimmune, Experimental | MNDR Database |
| hsa-miR-505-3p | nasopharynx carcinoma | MNDR Database |
| hsa-miR-505-3p | neurodegenerative disease | MNDR Database |
| hsa-miR-505-3p | neuromyelitis optica | MNDR Database |
| hsa-miR-505-3p | osteosarcoma | MNDR Database |
| hsa-miR-505-3p | pancreatic adenocarcinoma | MNDR Database |
| hsa-miR-505-3p | pancreatic cancer | MNDR Database |
| hsa-miR-505-3p | papillary renal cell carcinoma | MNDR Database |
| hsa-miR-505-3p | Parkinson's disease | MNDR Database |
| hsa-miR-505-3p | Precursor Cell Lymphoblastic Leukemia-Lymphoma | MNDR Database |
| hsa-miR-505-3p | progesterone-receptor positive breast cancer | MNDR Database |
| hsa-miR-505-3p | progressive supranuclear palsy | MNDR Database |
| hsa-miR-505-3p | prostate adenocarcinoma | MNDR Database |
| hsa-miR-505-3p | rectum adenocarcinoma | MNDR Database |
| hsa-miR-505-3p | relapsing-remitting multiple sclerosis | MNDR Database |
| hsa-miR-505-3p | renal clear cell carcinoma | MNDR Database |
| hsa-miR-505-3p | rheumatoid arthritis | MNDR Database |
| hsa-miR-505-3p | skin melanoma | MNDR Database |
| hsa-miR-505-3p | stomach cancer | MNDR Database |
| hsa-miR-505-3p | Stroke, Lacunar | MNDR Database |
| hsa-miR-505-3p | thyroid carcinoma | MNDR Database |
| hsa-miR-505-3p | uterine corpus endometrial carcinoma | MNDR Database |
| hsa-miR-505-3p | vascular disease | MNDR Database |
| hsa-miR-505-3p | noonan syndrome | eDGAR Database |
| hsa-miR-505-3p | schwannomatosis | eDGAR Database |