Interaction ID
ncRI-40893006
Interaction Molecules
mmu-miR-30b-3p -- Plxna2
Interaction Level
RNA-RNA
Interaction Class
binding
Data Source
TargetScan with Ago CLIP data
Tags
Organism
Mus musculus
Tissue or Cell Type
Keratinocytes cell
Experiment
AGO CLIP
Description
Conserved miRNAs target sites predicted by TargetScan and miRanda overlap with the AGO CLIP dataset
Alias
-
Class
mRNA
Ensembl id
ENSMUSG00000026640
Description
Coreceptor for SEMA3A and SEMA6A. Necessary for signaling by SEMA6A and class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration. Class 3 semaphorins bind to a complex composed of a neuropilin and a plexin. The plexin modulates the affinity of the complex for specific semaphorins, and its cytoplasmic domain is required for the activation of down- stream signaling events in the cytoplasm.
| Pubmed ID | 26203562 | Journal | eLife |
|---|---|---|---|
| Title | MicroRNA-203 represses selection and expansion of oncogenic Hras transformed tumor initiating cells. | ||
| Author | Riemondy K, Wang XJ, Torchia EC, Roop DR, Yi R | ||
| Molecule | Disease | Data Source |
|---|---|---|
| mmu-miR-30b-3p | Alzheimer's disease | MNDR Database |
| mmu-miR-30b-3p | amyotrophic lateral sclerosis | MNDR Database |
| mmu-miR-30b-3p | Brain Injury, Chronic | MNDR Database |
| mmu-miR-30b-3p | Chronic Pain | MNDR Database |
| mmu-miR-30b-3p | diabetic neuropathy | MNDR Database |
| mmu-miR-30b-3p | Down syndrome | MNDR Database |
| mmu-miR-30b-3p | Hearing Loss, Bilateral | MNDR Database |
| mmu-miR-30b-3p | Hyperalgesia | MNDR Database |
| mmu-miR-30b-3p | medulloblastoma | MNDR Database |
| mmu-miR-30b-3p | middle cerebral artery infarction | MNDR Database |
| mmu-miR-30b-3p | muscular disease | MNDR Database |
| mmu-miR-30b-3p | Myotonic Dystrophy | MNDR Database |
| mmu-miR-30b-3p | neurogenic bladder | MNDR Database |
| mmu-miR-30b-3p | Peripheral Nerve Injuries | MNDR Database |
| mmu-miR-30b-3p | relapsing-remitting multiple sclerosis | MNDR Database |
| mmu-miR-30b-3p | Rett syndrome | MNDR Database |
| mmu-miR-30b-3p | Seizures | MNDR Database |
| mmu-miR-30b-3p | sensorineural hearing loss | MNDR Database |
| mmu-miR-30b-3p | West Nile fever | MNDR Database |