Interaction: ncRI-40842517

Interaction Profile

Interaction ID

ncRI-40842517

Interaction Molecules

hsa-miR-548q -- NSUN4

Interaction Level

RNA-RNA

Interaction Class

binding

Data Source

miRanda with Ago CLIP data

Tags

Organism

Homo sapiens

Tissue or Cell Type

motor cortex

Experiment

AGO CLIP

Description

Conserved miRNAs target sites predicted by miRanda overlap with the AGO CLIP dataset

Molecule Profile

Alias

-

Class

miRNA

miRBase id

MI0010637

Description

Homo sapiens miR-548q stem-loop

Alias

-

Class

mRNA

Ensembl id

ENSG00000117481

Description

Involved in mitochondrial ribosome assembly. 5- methylcytosine rRNA methyltransferase that probably is involved in mitochondrial ribosome small subunit (SSU) maturation by methylation of mitochondrial 12S rRNA; the function is independent of MTERFD2/MTERF4 and assembled mitochondrial ribosome large subunit (LSU). Targeted to LSU by MTERFD2/MTERF4 and probably is involved in a final step in ribosome biogenesis to ensure that SSU and LSU are assembled. In vitro can methylate 16S rRNA of the LSU; the methylation is enhanced by MTERFD/MTERF4.

Reference Information
Pubmed ID 24389009 Journal Neuron
Title Transcriptome-wide discovery of microRNA binding sites in human brain.
Author Boudreau RL, Jiang P, Gilmore BL, Spengler RM, Tirabassi R, Nelson JA, Ross CA, Xing Y, Davidson BL
Network View
Disease Annotation
Molecule Disease Data Source
hsa-miR-548q breast cancer MNDR Database
hsa-miR-548q cholangiocarcinoma MNDR Database
hsa-miR-548q colon cancer MNDR Database
hsa-miR-548q colorectal cancer MNDR Database
hsa-miR-548q embryonal cancer MNDR Database
hsa-miR-548q hepatocellular carcinoma MNDR Database
hsa-miR-548q Hodgkin's lymphoma MNDR Database
hsa-miR-548q Liver Neoplasms MNDR Database
hsa-miR-548q stomach cancer MNDR Database