Interaction ID
ncRI-40730496
Interaction Molecules
hsa-miR-1203 -- CANX
Interaction Level
RNA-RNA
Interaction Class
binding
Data Source
miRanda with Ago CLIP data
Tags
Organism
Homo sapiens
Tissue or Cell Type
HEK293T;HEK293S;motor cortex
Experiment
AGO CLIP
Description
Conserved miRNAs target sites predicted by miRanda overlap with the AGO CLIP dataset
Alias
-
Class
mRNA
Ensembl id
ENSG00000127022
Description
Calcium-binding protein that interacts with newly synthesized glycoproteins in the endoplasmic reticulum. It may act in assisting protein assembly and/or in the retention within the ER of unassembled protein subunits. It seems to play a major role in the quality control apparatus of the ER by the retention of incorrectly folded proteins. Associated with partial T-cell antigen receptor complexes that escape the ER of immature thymocytes, it may function as a signaling complex regulating thymocyte maturation. Additionally it may play a role in receptor- mediated endocytosis at the synapse.
| Pubmed ID | 23824327 | Journal | Genes & development |
|---|---|---|---|
| Title | Remodeling of Ago2-mRNA interactions upon cellular stress reflects miRNA complementarity and correlates with altered translation rates. | ||
| Author | Karginov FV, Hannon GJ | ||
| Pubmed ID | 24389009 | Journal | Neuron |
|---|---|---|---|
| Title | Transcriptome-wide discovery of microRNA binding sites in human brain. | ||
| Author | Boudreau RL, Jiang P, Gilmore BL, Spengler RM, Tirabassi R, Nelson JA, Ross CA, Xing Y, Davidson BL | ||
| Pubmed ID | 29273203 | Journal | Journal of molecular biology |
|---|---|---|---|
| Title | Transcriptome-wide Identification and Validation of Interactions between the miRNA Machinery and HuR on mRNA Targets. | ||
| Author | Li Y, Estep JA, Karginov FV | ||
| Molecule | Disease | Data Source |
|---|---|---|
| hsa-miR-1203 | biliary tract cancer | MNDR Database |
| hsa-miR-1203 | colorectal cancer | MNDR Database |
| hsa-miR-1203 | esophagus small cell carcinoma | MNDR Database |
| hsa-miR-1203 | familiar ovarian carcinoma | MNDR Database |
| hsa-miR-1203 | Glioblastoma | MNDR Database |
| hsa-miR-1203 | hepatocellular carcinoma | MNDR Database |
| hsa-miR-1203 | nasopharynx carcinoma | MNDR Database |
| hsa-miR-1203 | pancreatic cancer | MNDR Database |
| hsa-miR-1203 | stomach cancer | MNDR Database |