Interaction Profile
Interaction ID
ncRI-40640154
Interaction Molecules
hsa-miR-661 -- MNT
Interaction Level
RNA-RNA
Interaction Class
binding
Data Source
miRanda with Ago CLIP data
Tags
Organism
Homo sapiens
Tissue or Cell Type
T-REx-293T
Experiment
AGO CLIP
Description
Conserved miRNAs target sites predicted by miRanda overlap with the AGO CLIP dataset
Molecule Profile
Alias
-
Class
mRNA
Ensembl id
ENSG00000070444
Description
Binds DNA as a heterodimer with MAX and represses transcription. Binds to the canonical E box sequence 5'-CACGTG-3' and, with higher affinity, to 5'-CACGCG-3'.
Reference Information
| Pubmed ID | 29273203 | Journal | Journal of molecular biology |
|---|---|---|---|
| Title | Transcriptome-wide Identification and Validation of Interactions between the miRNA Machinery and HuR on mRNA Targets. | ||
| Author | Li Y, Estep JA, Karginov FV | ||
Network View
Disease Annotation
| Molecule | Disease | Data Source |
|---|---|---|
| hsa-miR-661 | bone disease | MNDR Database |
| hsa-miR-661 | brain disease | MNDR Database |
| hsa-miR-661 | breast cancer | MNDR Database |
| hsa-miR-661 | Breast Neoplasms | MNDR Database |
| hsa-miR-661 | cancer | MNDR Database |
| hsa-miR-661 | carcinoma | MNDR Database |
| hsa-miR-661 | Carcinoma, Non-Small-Cell Lung | MNDR Database |
| hsa-miR-661 | cholangiocarcinoma | MNDR Database |
| hsa-miR-661 | Chronic Pain | MNDR Database |
| hsa-miR-661 | colon cancer | MNDR Database |
| hsa-miR-661 | colorectal cancer | MNDR Database |
| hsa-miR-661 | eye disease | MNDR Database |
| hsa-miR-661 | familiar ovarian carcinoma | MNDR Database |
| hsa-miR-661 | Glioblastoma | MNDR Database |
| hsa-miR-661 | heart disease | MNDR Database |
| hsa-miR-661 | Her2-receptor positive breast cancer | MNDR Database |
| hsa-miR-661 | leukemia | MNDR Database |
| hsa-miR-661 | lymphoma | MNDR Database |
| hsa-miR-661 | malignant glioma | MNDR Database |
| hsa-miR-661 | melanoma | MNDR Database |
| hsa-miR-661 | multiple myeloma | MNDR Database |
| hsa-miR-661 | neurodegenerative disease | MNDR Database |
| hsa-miR-661 | oral squamous cell carcinoma | MNDR Database |
| hsa-miR-661 | Ovarian Neoplasms | MNDR Database |
| hsa-miR-661 | pancreatic cancer | MNDR Database |
| hsa-miR-661 | progesterone-receptor negative breast cancer | MNDR Database |
| hsa-miR-661 | progesterone-receptor positive breast cancer | MNDR Database |
| hsa-miR-661 | retinoblastoma | MNDR Database |
| hsa-miR-661 | squamous cell carcinoma | MNDR Database |
| hsa-miR-661 | stomach cancer | MNDR Database |
| hsa-miR-661 | vascular disease | MNDR Database |