Interaction Profile
Interaction ID
ncRI-40638892
Interaction Molecules
hsa-miR-302b-3p -- ZNF711
Interaction Level
RNA-RNA
Interaction Class
binding
Data Source
miRanda with Ago CLIP data
Tags
Organism
Homo sapiens
Tissue or Cell Type
T-REx-293T
Experiment
AGO CLIP
Description
Conserved miRNAs target sites predicted by miRanda overlap with the AGO CLIP dataset
Molecule Profile
Alias
-
Class
mRNA
Ensembl id
ENSG00000147180
Description
Transcription regulator required for brain development. Probably acts as a transcription factor that binds to the promoter of target genes and recruits PHF8 histone demethylase, leading to activate expression of genes involved in neuron development, such as KDM5C.
Reference Information
| Pubmed ID | 23824327 | Journal | Genes & development |
|---|---|---|---|
| Title | Remodeling of Ago2-mRNA interactions upon cellular stress reflects miRNA complementarity and correlates with altered translation rates. | ||
| Author | Karginov FV, Hannon GJ | ||
| Pubmed ID | 29273203 | Journal | Journal of molecular biology |
|---|---|---|---|
| Title | Transcriptome-wide Identification and Validation of Interactions between the miRNA Machinery and HuR on mRNA Targets. | ||
| Author | Li Y, Estep JA, Karginov FV | ||
Network View
Disease Annotation
| Molecule | Disease | Data Source |
|---|---|---|
| hsa-miR-302b-3p | acute myeloid leukemia | MNDR Database |
| hsa-miR-302b-3p | Alzheimer's disease | MNDR Database |
| hsa-miR-302b-3p | astrocytoma | MNDR Database |
| hsa-miR-302b-3p | autosomal recessive disease | MNDR Database |
| hsa-miR-302b-3p | bone disease | MNDR Database |
| hsa-miR-302b-3p | brain disease | MNDR Database |
| hsa-miR-302b-3p | breast cancer | MNDR Database |
| hsa-miR-302b-3p | Breast Neoplasms | MNDR Database |
| hsa-miR-302b-3p | cancer | MNDR Database |
| hsa-miR-302b-3p | carcinoma | MNDR Database |
| hsa-miR-302b-3p | Carcinoma, Non-Small-Cell Lung | MNDR Database |
| hsa-miR-302b-3p | Cerebellar Neoplasms | MNDR Database |
| hsa-miR-302b-3p | cholangiocarcinoma | MNDR Database |
| hsa-miR-302b-3p | colon cancer | MNDR Database |
| hsa-miR-302b-3p | colorectal cancer | MNDR Database |
| hsa-miR-302b-3p | dermatomyositis | MNDR Database |
| hsa-miR-302b-3p | diabetes mellitus | MNDR Database |
| hsa-miR-302b-3p | dilated cardiomyopathy | MNDR Database |
| hsa-miR-302b-3p | dyspepsia | MNDR Database |
| hsa-miR-302b-3p | embryonal carcinoma | MNDR Database |
| hsa-miR-302b-3p | eye disease | MNDR Database |
| hsa-miR-302b-3p | Eye Abnormalities | MNDR Database |
| hsa-miR-302b-3p | familiar ovarian carcinoma | MNDR Database |
| hsa-miR-302b-3p | fragile X syndrome | MNDR Database |
| hsa-miR-302b-3p | gastric adenocarcinoma | MNDR Database |
| hsa-miR-302b-3p | gastric lymphoma | MNDR Database |
| hsa-miR-302b-3p | germ cell and embryonal cancer | MNDR Database |
| hsa-miR-302b-3p | Glioblastoma | MNDR Database |
| hsa-miR-302b-3p | head and neck cancer | MNDR Database |
| hsa-miR-302b-3p | Heart Failure | MNDR Database |
| hsa-miR-302b-3p | hepatocellular carcinoma | MNDR Database |
| hsa-miR-302b-3p | Her2-receptor positive breast cancer | MNDR Database |
| hsa-miR-302b-3p | Hodgkin's lymphoma | MNDR Database |
| hsa-miR-302b-3p | Huntington's disease | MNDR Database |
| hsa-miR-302b-3p | hypersensitivity reaction type II disease | MNDR Database |
| hsa-miR-302b-3p | intellectual disability | MNDR Database |
| hsa-miR-302b-3p | keratoconus | MNDR Database |
| hsa-miR-302b-3p | leukemia | MNDR Database |
| hsa-miR-302b-3p | Liver Cirrhosis, Biliary | MNDR Database |
| hsa-miR-302b-3p | lung adenocarcinoma | MNDR Database |
| hsa-miR-302b-3p | lung cancer | MNDR Database |
| hsa-miR-302b-3p | lung disease | MNDR Database |
| hsa-miR-302b-3p | lung squamous cell carcinoma | MNDR Database |
| hsa-miR-302b-3p | Lymphoblastoid | MNDR Database |
| hsa-miR-302b-3p | malignant glioma | MNDR Database |
| hsa-miR-302b-3p | malignant pleural mesothelioma | MNDR Database |
| hsa-miR-302b-3p | medulloblastoma | MNDR Database |
| hsa-miR-302b-3p | melanoma | MNDR Database |
| hsa-miR-302b-3p | multiple myeloma | MNDR Database |
| hsa-miR-302b-3p | Neoplasms | MNDR Database |
| hsa-miR-302b-3p | nephroblastoma | MNDR Database |
| hsa-miR-302b-3p | neurodegenerative disease | MNDR Database |
| hsa-miR-302b-3p | oral squamous cell carcinoma | MNDR Database |
| hsa-miR-302b-3p | Ovarian Neoplasms | MNDR Database |
| hsa-miR-302b-3p | pancreatic cancer | MNDR Database |
| hsa-miR-302b-3p | pancreatic ductal adenocarcinoma | MNDR Database |
| hsa-miR-302b-3p | pre-eclampsia | MNDR Database |
| hsa-miR-302b-3p | progesterone-receptor negative breast cancer | MNDR Database |
| hsa-miR-302b-3p | progesterone-receptor positive breast cancer | MNDR Database |
| hsa-miR-302b-3p | Prostatic Neoplasms | MNDR Database |
| hsa-miR-302b-3p | relapsing-remitting multiple sclerosis | MNDR Database |
| hsa-miR-302b-3p | renal cell carcinoma | MNDR Database |
| hsa-miR-302b-3p | Seizures | MNDR Database |
| hsa-miR-302b-3p | skin cancer | MNDR Database |
| hsa-miR-302b-3p | squamous cell carcinoma | MNDR Database |
| hsa-miR-302b-3p | stomach cancer | MNDR Database |
| hsa-miR-302b-3p | syndrome | MNDR Database |
| hsa-miR-302b-3p | systemic mastocytosis | MNDR Database |
| hsa-miR-302b-3p | temporal lobe epilepsy | MNDR Database |
| hsa-miR-302b-3p | teratocarcinoma | MNDR Database |
| hsa-miR-302b-3p | thyroid cancer | MNDR Database |
| hsa-miR-302b-3p | tonsil cancer | MNDR Database |
| hsa-miR-302b-3p | Urinary Bladder Neoplasms | MNDR Database |
| hsa-miR-302b-3p | uterine cancer | MNDR Database |
| hsa-miR-302b-3p | vascular disease | MNDR Database |
| hsa-miR-302b-3p | mental retardation, nonsyndromic, x-linked | eDGAR Database |