Interaction ID
ncRI-40033104
Interaction Molecules
mmu-mir-148b -- Dmbt1
Interaction Level
RNA-RNA
Interaction Class
regulatory
Data Source
High-throughput data
Tags
Organism
Mus musculus
Tissue or Cell Type
mouse intestine
Experiment
HITS-CLIP
Description
Combining the mRNA microarray data with HITS-CLIP-derived targeting information identifies a set of miRNA targets whose expression levels are affected in the small intestine by deletion of Dicer1.
Alias
Dmbt1
Class
protein
UniProt id
Description
May play roles in mucosal defense system and cellular immune defense. May play a role in liver regeneration. May be an important factor in fate decision and differentiation of transit-amplifying ductular (oval) cells within the hepatic lineage. May function as a binding protein in saliva for the regulation of taste sensation. May play a role as an opsonin receptor for SFTPD and SPAR in macrophage tissues throughout the body, including epithelial cells lining the gastrointestinal tract (By simila
| Pubmed ID | 20659473 | Journal | Gastroenterology |
|---|---|---|---|
| Title | MicroRNAs control intestinal epithelial differentiation, architecture, and barrier function. | ||
| Author | McKenna LB, Schug J, Vourekas A, McKenna JB, Bramswig NC, Friedman JR, Kaestner KH | ||
| Molecule | Disease | Data Source |
|---|---|---|
| mmu-mir-148b | amyotrophic lateral sclerosis | MNDR Database |
| mmu-mir-148b | Chronic Pain | MNDR Database |
| mmu-mir-148b | Epilepsia Partialis Continua | MNDR Database |
| mmu-mir-148b | Hearing Loss, Bilateral | MNDR Database |
| mmu-mir-148b | medulloblastoma | MNDR Database |
| mmu-mir-148b | Rett syndrome | MNDR Database |
| mmu-mir-148b | Seizures | MNDR Database |
| mmu-mir-148b | sensorineural hearing loss | MNDR Database |
| mmu-mir-148b | Spinal Cord Compression | MNDR Database |