Interaction ID

ncRI-40006502

Interaction Molecules

U6 -- Lsm6

Interaction Level

RNA-Protein

Interaction Class

binding

Data Source

Literature mining

Tags

Organism

Homo sapiens

Tissue or Cell Type

-

Experiment

Immunoprecipitation experiments

Description

Immunoprecipitation revealed that an evolutionarily related subgroup of seven Sm-like proteins is directly associated with the nuclear U6. These proteins appear functionally important to stabilize U6 snRNA.

Alias

-

Class

lncRNA

NONCODE id

NONHSAT116310

Description

-

Alias

-

Class

protein

UniProt id

P62312

Description

Component of LSm protein complexes, which are involved in RNA processing and may function in a chaperone-like manner, facilitating the efficient association of RNA processing factors with their substrates. Component of the cytoplasmic LSM1-LSM7 complex, which is thought to be involved in mRNA degradation by activating the decapping step in the 5'-to-3' mRNA decay pathway. Component of the nuclear LSM2-LSM8 complex, which is involved in splicing of nuclear mRNAs. LSM2-LSM8 associates with multipl