Variable Number Tandem Repeat (VNTR) refers to a type of DNA sequence characterized by a specific segment of nucleotides that is repeated multiple times in tandem. The number of repeats can vary among individuals in a population, leading to genetic diversity. Their repeating units are called motifs, and a single VNTR locus may contain multiple repeating units.
We conducted a comprehensive VNTR study in 8,222 high-coverage genomes, exploring their polymorphisms in both length and repeating units. Ultimately, we identified a total of 2.5 million length polymorphisms and 11 million motif polymorphismsamong the 916,938 motifs at 38,685 loci (for details, see the methods section).
Center for Big Data Research in Health,
Institute of Biophysics,
Chinese Academy of Sciences.
Beijing, P.R.China, 100101
Email: SijiaZhang (sjzhang95@126.com);
QiaoSong (songqiao18@mails.ucas.ac.cn);
Principal Investigator: Shunmin He (heshunmin@ibp.ac.cn)
© 2024. Center for Big Data Research in Health, Key Laboratory of RNA Biology, Institute of Biophysics, Chinese Academy of Sciences